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Akademický článek

Postmortem transcriptional profiling reveals widespread increase in inflammation in schizophrenia: a comparison of prefrontal cortex, striatum, and hippocampus among matched tetrads of controls with subjects diagnosed with schizophrenia, bipolar or major depressive disorder.

Autor: Lanz TA; Translational Biology, Biogen, Cambridge, MA, UK. tom_lanz@yahoo.com., Reinhart V; Alzheimer's Disease Research Unit, Biogen, Cambridge, MA, UK., Sheehan MJ; Translational Biology, Biogen, Cambridge, MA, UK., Rizzo SJS; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Aging Institute, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Bove SE; Life Technologies, New London, CT, UK., James LC; Internal Medicine, Pfizer, Cambridge, MA, USA., Volfson D; Neuroscience Analytics, Takeda Pharmaceuticals, Cambridge, MA, UK., Lewis DA; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA., Kleiman RJ; Translational Biology, Biogen, Cambridge, MA, UK.

Publikováno v: Translational psychiatry [Transl Psychiatry] 2019 May 23; Vol. 9 (1), pp. 151. Date of Electronic Publication: 2019 May 23.

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Akademický článek

Evaluation of TrkB and BDNF transcripts in prefrontal cortex, hippocampus, and striatum from subjects with schizophrenia, bipolar disorder, and major depressive disorder.

Autor: Reinhart V; Neuroscience, Pfizer Inc., Cambridge, MA, USA., Bove SE; Life Technologies, New London, CT, USA., Volfson D; Research Statistics, Pfizer Inc., Cambridge, MA, USA., Lewis DA; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA., Kleiman RJ; Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA., Lanz TA; Neuroscience, Pfizer Inc., Cambridge, MA, USA. Electronic address: Thomas.a.lanz@pfizer.com.

Publikováno v: Neurobiology of disease [Neurobiol Dis] 2015 May; Vol. 77, pp. 220-7. Date of Electronic Publication: 2015 Mar 18.

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Akademický článek

Robust changes in expression of brain-derived neurotrophic factor (BDNF) mRNA and protein across the brain do not translate to detectable changes in BDNF levels in CSF or plasma.

Autor: Lanz TA; Pfizer Global Research and Development, Groton, CT 06340, USA. thomas.a.lanz@pfizer.com, Bove SE, Pilsmaker CD, Mariga A, Drummond EM, Cadelina GW, Adamowicz WO, Swetter BJ, Carmel S, Dumin JA, Kleiman RJ

Publikováno v: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals [Biomarkers] 2012 Sep; Vol. 17 (6), pp. 524-31. Date of Electronic Publication: 2012 Jun 07.

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Akademický článek

Chronic suppression of phosphodiesterase 10A alters striatal expression of genes responsible for neurotransmitter synthesis, neurotransmission, and signaling pathways implicated in Huntington's disease.

Autor: Kleiman RJ; Neuroscience Research Unit, Eastern Point Road, Pfizer Global Research and Development, Groton, CT 06379, USA. robin.j.kleiman@pfizer.com, Kimmel LH, Bove SE, Lanz TA, Harms JF, Romegialli A, Miller KS, Willis A, des Etages S, Kuhn M, Schmidt CJ

Publikováno v: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2011 Jan; Vol. 336 (1), pp. 64-76. Date of Electronic Publication: 2010 Oct 05.

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Akademický článek

New advances in musculoskeletal pain.

Autor: Bove SE; Department of Neurosciences Biology, Pfizer Global Research and Development, Groton Laboratories, Groton, CT, USA., Flatters SJ, Inglis JJ, Mantyh PW

Publikováno v: Brain research reviews [Brain Res Rev] 2009 Apr; Vol. 60 (1), pp. 187-201. Date of Electronic Publication: 2008 Dec 25.

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