Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Bouyoukou Hounkpatin A"'
Autor:
Mouwenda, Yoanne D, Betouke Ongwe, Eunice, Nkoma Mouima, Anne-Marie, Nouatin, Odilon P, Edoa, Jean R, Manouana, Prince G, Pinto de Jesus, Susana, Kühne, Vera, Mordmueller, Benjamin, Lell, Bertrand, Agnandji, Selidji T, Koehler, Carsten, Adegnika, Ayola A *, de Vries, Sophia G *, Zinsou, Frejus J, Honkepehedji, Yabo J, Dejon Agobé, Jean-Claude, Vodonou, Kafui G, Bikangui, Rodrigue, Bouyoukou Hounkpatin, Aurore, Bache, Emmanuel B, Massinga Loembe, Marguerite, van Leeuwen, Remko, Molemans, Marjan, Kremsner, Peter G, Yazdanbakhsh, Maria, Hotez, Peter J, Bottazzi, Maria Elena, Li, Guangzhao, Bethony, Jeffrey M, Diemert, David J *, Grobusch, Martin P
Publikováno v:
In The Lancet Infectious Diseases February 2021 21(2):275-285
Autor:
Odilon Nouatin, Juliana Boex Mengue, Jean Claude Dejon-Agobé, Rolf Fendel, Javier Ibáñez, Ulysse Ateba Ngoa, Jean Ronald Edoa, Bayodé Roméo Adégbité, Yabo Josiane Honkpéhédji, Jeannot Fréjus Zinsou, Aurore Bouyoukou Hounkpatin, Kabirou Moutairou, Andreas Homoet, Meral Esen, Andrea Kreidenweiss, Stephen L Hoffman, Michael Theisen, Adrian J F Luty, Bertrand Lell, Selidji Todagbe Agnandji, Ghyslain Mombo-Ngoma, Michael Ramharter, Peter Kremsner, Benjamin Mordmüller, Ayôla Akim Adegnika
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009361 (2021)
BackgroundHelminths can modulate the host immune response to Plasmodium falciparum and can therefore affect the risk of clinical malaria. We assessed here the effect of helminth infections on both the immunogenicity and efficacy of the GMZ2 malaria v
Externí odkaz:
https://doaj.org/article/bb9e94c7a35042c8863884855ee8d7a3
Publikováno v:
Infection and Drug Resistance. 12:553-570
Tafenoquine is an 8-aminoquinoline with activity against all human life cycle stages of Plasmodium vivax, including dormant liver stages - so called hypnozoites. Its long half-life of ~15 days is allowing for a single exposure regimen. It has been un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00e1a040dfd08ccab18b827c09dd2eeb
https://doi.org/10.2147/idr.s151031
https://doi.org/10.2147/idr.s151031
Autor:
Martin P. Grobusch, Frejus Jeannot Zinsou, Peter G. Kremsner, Remko van Leeuwen, David Diemert, Sophia G. de Vries, Eunice M Betouke Ongwe, Benjamin Mordmueller, Marjan Molemans, Odilon Nouatin, Susana Pinto de Jesus, Jean-Claude Dejon Agobe, Ayola A. Adegnika, Emmanuel B. Bache, Selidji T Agnandji, Yabo J Honkepehedji, Kafui G Vodonou, Rodrigue Bikangui, Prince G Manouana, Peter J. Hotez, Bertrand Lell, Aurore Bouyoukou Hounkpatin, Maria Yazdanbakhsh, Marguerite Massinga Loembe, Anne-Marie Nkoma Mouima, Jean Ronald Edoa, Carsten Koehler, Guangzhao Li, Yoanne D. Mouwenda, Vera Kühne, Maria Elena Bottazzi, Jeffrey M. Bethony
Publikováno v:
The Lancet Infectious Diseases
The Lancet Infectious Diseases, 21(2), 275-285. ELSEVIER SCI LTD
The Lancet Infectious Diseases, 21(2), 275-285. ELSEVIER SCI LTD
Background Hookworms cause substantial morbidity in children and women of reproductive age. The control strategy of mass drug administration is suboptimal, hence the need for a vaccine. Necator americanus aspartic protease-1 (Na-APR-1) and N american
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb55fd2ffad7c271f775a2b2d818cb0
https://hdl.handle.net/1887/3214678
https://hdl.handle.net/1887/3214678
Autor:
Rolf Fendel, Peter G. Kremsner, Benjamin Mordmüller, Juliana Boex Mengue, Andreas Homoet, Meral Esen, Jeannot Fréjus Zinsou, Jean Ronald Edoa, Michael Ramharter, Ulysse Ateba Ngoa, Michael Theisen, Bayode Romeo Adegbite, Adrian J. F. Luty, Andrea Kreidenweiss, Yabo Josiane Honkpehedji, Ghyslain Mombo-Ngoma, Jean Claude Dejon-Agobé, Odilon Nouatin, Bertrand Lell, Kabirou Moutairou, Selidji T Agnandji, Javier Ibáñez, Stephen L. Hoffman, Aurore Bouyoukou Hounkpatin, Ayola A. Adegnika
Publikováno v:
PLoS Neglected Tropical Diseases
Nouatin, O, Mengue, J B, Dejon-Agobé, J C, Fendel, R, Ibáñez, J, Ngoa, U A, Edoa, J R, Adégbité, B R, Honkpéhédji, Y J, Zinsou, J F, Hounkpatin, A B, Moutairou, K, Homoet, A, Esen, M, Kreidenweiss, A, Hoffman, S L, Theisen, M, Luty, A J F, Lell, B, Agnandji, S T, Mombo-Ngoma, G, Ramharter, M, Kremsner, P, Mordmüller, B & Adegnika, A A 2021, ' Exploratory analysis of the effect of helminth infection on the immunogenicity and efficacy of the asexual blood-stage malaria vaccine candidate GMZ2 ', PLoS Neglected Tropical Diseases, vol. 15, no. 6, e0009361 . https://doi.org/10.1371/journal.pntd.0009361
PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009361 (2021)
Plos Neglected Tropical Diseases, 15, 6
Plos Neglected Tropical Diseases, 15
Nouatin, O, Mengue, J B, Dejon-Agobé, J C, Fendel, R, Ibáñez, J, Ngoa, U A, Edoa, J R, Adégbité, B R, Honkpéhédji, Y J, Zinsou, J F, Hounkpatin, A B, Moutairou, K, Homoet, A, Esen, M, Kreidenweiss, A, Hoffman, S L, Theisen, M, Luty, A J F, Lell, B, Agnandji, S T, Mombo-Ngoma, G, Ramharter, M, Kremsner, P, Mordmüller, B & Adegnika, A A 2021, ' Exploratory analysis of the effect of helminth infection on the immunogenicity and efficacy of the asexual blood-stage malaria vaccine candidate GMZ2 ', PLoS Neglected Tropical Diseases, vol. 15, no. 6, e0009361 . https://doi.org/10.1371/journal.pntd.0009361
PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009361 (2021)
Plos Neglected Tropical Diseases, 15, 6
Plos Neglected Tropical Diseases, 15
Background Helminths can modulate the host immune response to Plasmodium falciparum and can therefore affect the risk of clinical malaria. We assessed here the effect of helminth infections on both the immunogenicity and efficacy of the GMZ2 malaria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f2c7aac0a79ea503c3dbd970afe03e
https://pubmed.ncbi.nlm.nih.gov/34061838
https://pubmed.ncbi.nlm.nih.gov/34061838
Autor:
Stephen L. Hoffman, Jean Claude Dejon-Agobé, Benjamin Mordmüller, Fabrice Lotola Mougeni, Saadou Issifou, Odilon Nouatin, Selidji T Agnandji, Javier Ibáñez, Jean Ronald Edoa, Ulysse Ateba Ngoa, Bertrand Lell, Meral Esen, Peter G. Kremsner, Aurore Bouyoukou Hounkpatin, Sina Brückner, Kabirou Moutairou, Marguerite Massinga Loembe, Ayola A. Adegnika, Adrian J. F. Luty, Michael Theisen
Publikováno v:
Vaccine
Background Despite appreciable immunogenicity in malaria-naive populations, many candidate malaria vaccines are considerably less immunogenic in malaria-exposed populations. This could reflect induction of immune regulatory mechanisms involving Human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb9b0851aa77419deb9cccd17273ebd
https://europepmc.org/articles/PMC7297038/
https://europepmc.org/articles/PMC7297038/
Autor:
Saadou Issifou, Matthias Schwab, Peter G. Kremsner, Charles R. Newton, Kalifa Bojang, Daniel Ansong, Godfrey Allan Otieno, Benjamin Mordmüller, Mirjam C. K. Geditz, Sanjeev Krishna, Maryvonne Kombila, Aurore Bouyoukou Hounkpatin, Uduak Okomo, Marielle K. Bouyou-Akotet, Jeannot Fréjus Zinsou, Michael Kazungu, Reinhold Kerb, Stefanie Bolte, Frank Sanya-Isijola, Carsten Köhler, Denise P. Mawili Mboumba, Alice Liomba, Thomas Engleitner, A.A. Adegnika, Thirumalaisamy P. Velavan, Terrie E. Taylor, Bernhards Ogutu, Yamikani Chimalizeni, Patricia Njuguna, Christian N. Nguetse, Justice Sylverken, Anne Wangwe, Tsiri Agbenyega
Publikováno v:
PLoS Medicine, Vol 13, Iss 1, p e1001938 (2016)
PLoS Medicine
PLoS Medicine
Background Current artesunate (ARS) regimens for severe malaria are complex. Once daily intramuscular (i.m.) injection for 3 d would be simpler and more appropriate for remote health facilities than the current WHO-recommended regimen of five intrave
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745d964f4c242667a960b9bb95ec058c
https://doaj.org/article/3f43611bd8744f1397fef56ebb792a00
https://doaj.org/article/3f43611bd8744f1397fef56ebb792a00
Autor:
John Lyimo, Owusu Boahen, Salim Abdulla, Stephen Apanga, Marcel Tanner, Kingsley Kayan, Saadou Issifou, Mwanajaa Shomari, Kwaku Poku Asante, Maria Chikawe, Maria Paricek, Didier Lapierre, Joe Cohen, Nahya Salim, Ruth Owusu, Rose Minja, Marla Sillman, Marie-Claude Dubois, David Dosoo, Solange Soulanoudjingar, Grace Mwangoka, Christian Loucq, Amanda J. Leach, Barbara Savarese, Tina Möller, Selidji T Agnandji, Bertrand Lell, Aurore Bouyoukou Hounkpatin, Erik Jongert, Brian Greenwood, Johan Vekemans, Terrell Carter, José Francisco Fernandes, Seth Owusu-Agyei, Peter G. Kremsner, Marc Lievens, Kingsley Osei-Kwakye, Evans Kwara, Tigani Madi, Preeti Vansadia, Daniel Chandramohan, George Adjei
Publikováno v:
The Lancet Infectious Diseases. 11:741-749
BACKGROUND The RTS,S/AS01(E) candidate malaria vaccine is being developed for immunisation of infants in Africa through the expanded programme on immunisation (EPI). 8 month follow-up data have been reported for safety and immunogenicity of RTS,S/AS0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27b31a2e30879a5e93298504ed4706b
https://doi.org/10.1016/s1473-3099(11)70100-1
https://doi.org/10.1016/s1473-3099(11)70100-1
Autor:
Frejus Jeannot Zinsou, Martin P. Grobusch, Jeffrey M. Bethony, Jean Claude Dejon, Bache Emmanuel Bache, Sophie De Vries, Maria Yazdanbakhsh, Nadine Pakker, Remko van Leeuwen, Peter G. Kremsner, Josiane Honkpehedji, Marguerite Massinga Loembe, Peter J. Hotez, Aurore Bouyoukou Hounkpatin, David Diemert, Ayola A. Adegnika, Bertrand Lell
Publikováno v:
BMJ Global Health. 2:A12.3-A13
Background Hookworm disease is one of the most prevalent of the neglected tropical diseases. To date, the control of hookworm infection has been limited to mass-administration of anthelminthic drugs. Despite this, the global hookworm prevalence does
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8ccc3225450023dd9d53f5f19fe6663
https://doi.org/10.1136/bmjgh-2016-000260.29
https://doi.org/10.1136/bmjgh-2016-000260.29
Autor:
Peter G. Kremsner, Søren Jepsen, Severin Olesen-Larsen, Benjamin Mordmüller, Ulysse Ateba-Ngoa, Saadou Issifou, Micha Phill Grønholm Jepsen, Aurore Bouyoukou Hounkpatin, Michael Christiansen, Morten Hanefeld Dziegiel, Susheel K. Singh, Michael Theisen, Prajakta S. Jogdand, Meral Esen
Publikováno v:
The Journal of infectious diseases. 208(3)
Background. GMZ2 is a hybrid protein consisting of the N-terminal region of the glutamate-rich protein fused in frame to the C-terminal region of merozoite surface protein 3 (MSP3). GMZ2 formulated in Al(OH)3 has been tested in 3 published phase 1 cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc27eb21f882000b8f054fcd91e78d2
https://pubmed.ncbi.nlm.nih.gov/23624363
https://pubmed.ncbi.nlm.nih.gov/23624363