Toward Understanding How Staphylococcal Protein A Inhibits IgG-Mediated Phagocytosis

Autor: Cruz, Ana Rita, Bentlage, Arthur E H, Blonk, Robin, de Haas, Carla J C, Aerts, Piet C, Scheepmaker, Lisette M, Bouwmeester, Inge G, Lux, Anja, van Strijp, Jos A G, Nimmerjahn, Falk, van Kessel, Kok P M, Vidarsson, Gestur, Rooijakkers, Suzan H M, Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics

Publikováno v: Journal of Immunology, 209(6), 1146. American Association of Immunologists
Journal of Immunology, 209(6), 1146-1155. American Association of Immunologists

IgG molecules are crucial for the human immune response against bacterial infections. IgGs can trigger phagocytosis by innate immune cells, like neutrophils. To do so, IgGs should bind to the bacterial surface via their variable Fab regions and inter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4787bbc5ea6d493a41b557e83d6ee51f
https://dspace.library.uu.nl/handle/1874/426909