CCR7+ selected gene-modified T cells maintain a central memory phenotype and display enhanced persistence in peripheral blood in vivo

Autor: Kueberuwa, Gray, Gornall, Hannah, Alcantar-Orozco, Erik Marcelo, Bouvier, Deborah, Kapacee, Zainul Abedin, Hawkins, Robert Edward, Gilham, David Edward

Publikováno v: Kueberuwa, G, Gornall, H, Alcantar Orozco, E M, Bouvier, D, Kapacee, Z A, Hawkins, R & Gilham, D 2017, ' CCR7+ selected gene-modified T cells maintain a central memory phenotype and display enhanced persistence in peripheral blood in vivo ', Journal for ImmunoTherapy of Cancer, vol. 5, no. 14 . https://doi.org/10.1186/s40425-017-0216-7

BackgroundAdoptive T cell immunotherapy (ATCT) for cancer entails infusing patients with T cells that recognise and destroy tumour cells. Efficient engraftment of T cells and persistence in the circulation correlate with favourable clinical outcomes.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d8050bab2ff4d3a0bb0d26857e01bb57
https://research.manchester.ac.uk/en/publications/05e6fa79-c6ab-43d2-822d-33da43c53bb3

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