Associations between infant fungal and bacterial dysbiosis and childhood atopic wheeze in a nonindustrialized setting

Autor: Arrieta, M-C, Arévalo, A, Stiemsma, L, Dimitriu, P, Chico, ME, Loor, S, Vaca, M, Boutin, RCT, Morien, E, Jin, M, Turvey, SE, Walter, J, Parfrey, LW, Cooper, PJ, Finlay, B

Publikováno v: The Journal of Allergy and Clinical Immunology

Background Asthma is the most prevalent chronic disease of childhood. Recently, we identified a critical window early in the life of both mice and Canadian infants during which gut microbial changes (dysbiosis) affect asthma development. Given geogra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8c09d909817c04708c981f41669815a7
http://europepmc.org/articles/PMC6075469

Longitudinal body mass index trajectories at preschool age: children with rapid growth have differential composition of the gut microbiota in the first year of life.

Autor: Reyna ME; Translational Medicine Program, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada., Petersen C; Department of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada., Dai DLY; Department of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada., Dai R; Translational Medicine Program, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada., Becker AB; Section of Allergy and Immunology, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada.; Developmental Origins of Chronic Diseases in Children Network (DEVOTION), Children's Hospital, Winnipeg, MB, Canada., Azad MB; Section of Allergy and Immunology, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada.; Developmental Origins of Chronic Diseases in Children Network (DEVOTION), Children's Hospital, Winnipeg, MB, Canada.; Department of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, MB, Canada., Miliku K; Department of Medicine, McMaster University, Hamilton, ON, Canada., Lefebvre DL; Department of Medicine, McMaster University, Hamilton, ON, Canada., Moraes TJ; Translational Medicine Program, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada., Mandhane PJ; Department of Pediatrics, University of Alberta, Edmonton, AB, Canada., Boutin RCT; Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada., Finlay BB; Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada.; Michael Smith Laboratories, UBC, Vancouver, BC, Canada.; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada., Simons E; Section of Allergy and Immunology, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada., Kozyrskyj AL; Department of Pediatrics, University of Alberta, Edmonton, AB, Canada., Lou W; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada., Turvey SE; Department of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada., Subbarao P; Translational Medicine Program, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada. padmaja.subbarao@sickkids.ca.; Department of Medicine, McMaster University, Hamilton, ON, Canada. padmaja.subbarao@sickkids.ca.; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada. padmaja.subbarao@sickkids.ca.

Publikováno v: International journal of obesity (2005) [Int J Obes (Lond)] 2022 Jul; Vol. 46 (7), pp. 1351-1358. Date of Electronic Publication: 2022 Apr 15.

A rich meconium metabolome in human infants is associated with early-life gut microbiota composition and reduced allergic sensitization.

Autor: Petersen C; Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada.; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.; British Columbia Children's Hospital, Vancouver, BC, Canada., Dai DLY; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.; British Columbia Children's Hospital, Vancouver, BC, Canada., Boutin RCT; Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada., Sbihi H; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.; British Columbia Children's Hospital, Vancouver, BC, Canada., Sears MR; McMaster University, Hamilton, ON, Canada., Moraes TJ; Hospital for Sick Children & University of Toronto, Toronto, ON, Canada., Becker AB; Children's Hospital Research Institute of Manitoba, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada., Azad MB; Children's Hospital Research Institute of Manitoba, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada., Mandhane PJ; University of Alberta, Edmonton, AB, Canada., Subbarao P; McMaster University, Hamilton, ON, Canada.; Hospital for Sick Children & University of Toronto, Toronto, ON, Canada., Turvey SE; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.; British Columbia Children's Hospital, Vancouver, BC, Canada., Finlay BB; Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada.; Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada.; Department of Biochemistry, University of British Columbia, Vancouver, BC, Canada.

Publikováno v: Cell reports. Medicine [Cell Rep Med] 2021 Apr 29; Vol. 2 (5), pp. 100260. Date of Electronic Publication: 2021 Apr 29 (Print Publication: 2021).

Decreasing antibiotic use, the gut microbiota, and asthma incidence in children: evidence from population-based and prospective cohort studies.

Autor: Patrick DM; School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada; British Columbia Centre for Disease Control, Vancouver, BC, Canada. Electronic address: david.patrick@ubc.ca., Sbihi H; School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada; British Columbia Children's Hospital, Vancouver, BC, Canada., Dai DLY; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada; British Columbia Children's Hospital, Vancouver, BC, Canada., Al Mamun A; School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada; British Columbia Centre for Disease Control, Vancouver, BC, Canada., Rasali D; British Columbia Centre for Disease Control, Vancouver, BC, Canada., Rose C; School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada; British Columbia Centre for Disease Control, Vancouver, BC, Canada., Marra F; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada., Boutin RCT; Michael Smith Laboratories and Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada., Petersen C; Michael Smith Laboratories and Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada., Stiemsma LT; Natural Science Division, Pepperdine University, Malibu, CA, USA., Winsor GL; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada., Brinkman FSL; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada., Kozyrskyj AL; University of Alberta, Edmonton, AB, Canada., Azad MB; University of Manitoba, Winnipeg, MB, Canada., Becker AB; University of Manitoba, Winnipeg, MB, Canada., Mandhane PJ; University of Alberta, Edmonton, AB, Canada., Moraes TJ; The Hospital for Sick Children, Toronto, ON, Canada., Sears MR; Department of Medicine, McMaster University, Hamilton, ON, Canada., Subbarao P; The Hospital for Sick Children, Toronto, ON, Canada., Finlay BB; Michael Smith Laboratories and Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada., Turvey SE; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada; British Columbia Children's Hospital, Vancouver, BC, Canada. Electronic address: sturvey@cw.bc.ca.

Publikováno v: The Lancet. Respiratory medicine [Lancet Respir Med] 2020 Nov; Vol. 8 (11), pp. 1094-1105. Date of Electronic Publication: 2020 Mar 24.

Breastmilk Feeding Practices Are Associated with the Co-Occurrence of Bacteria in Mothers' Milk and the Infant Gut: the CHILD Cohort Study.

Autor: Fehr K; Children's Hospital Research Institute of Manitoba and Developmental Origins of Chronic Diseases in Children Network (DEVOTION), Winnipeg, MB, Canada; Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada., Moossavi S; Children's Hospital Research Institute of Manitoba and Developmental Origins of Chronic Diseases in Children Network (DEVOTION), Winnipeg, MB, Canada; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada; Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Sbihi H; Department of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada., Boutin RCT; Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada; Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada., Bode L; Department of Pediatrics and Larsson-Rosenquist Foundation Mother-Milk-Infant Center of Research Excellence (MOMI CORE), University of California San Diego, La Jolla, CA, USA., Robertson B; Department of Pediatrics and Larsson-Rosenquist Foundation Mother-Milk-Infant Center of Research Excellence (MOMI CORE), University of California San Diego, La Jolla, CA, USA., Yonemitsu C; Department of Pediatrics and Larsson-Rosenquist Foundation Mother-Milk-Infant Center of Research Excellence (MOMI CORE), University of California San Diego, La Jolla, CA, USA., Field CJ; Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada., Becker AB; Children's Hospital Research Institute of Manitoba and Developmental Origins of Chronic Diseases in Children Network (DEVOTION), Winnipeg, MB, Canada; Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada; Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Mandhane PJ; Department of Pediatrics, University of Alberta, Edmonton, AB, Canada., Sears MR; Department of Medicine, McMaster University, Hamilton, ON, Canada., Khafipour E; Department of Animal Science, University of Manitoba, Winnipeg, MB, Canada., Moraes TJ; Department of Pediatrics Hospital for Sick Children, University of Toronto, Toronto, ON, Canada., Subbarao P; Department of Pediatrics Hospital for Sick Children, University of Toronto, Toronto, ON, Canada; Department of Physiology, University of Toronto, Toronto, ON, Canada., Finlay BB; Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada; Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada. Electronic address: bfinlay@msl.ubc.ca., Turvey SE; Department of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: sturvey@bcchr.ca., Azad MB; Children's Hospital Research Institute of Manitoba and Developmental Origins of Chronic Diseases in Children Network (DEVOTION), Winnipeg, MB, Canada; Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada. Electronic address: meghan.azad@umanitoba.ca.

Publikováno v: Cell host & microbe [Cell Host Microbe] 2020 Aug 12; Vol. 28 (2), pp. 285-297.e4. Date of Electronic Publication: 2020 Jul 10.