The interplay of the macrophage tetraspan MS4A4A with Dectin-1 and its role in NK cell-mediated resistance to metastasis

Autor: Mattiola, I, Tomay, F, De Pizzol, M, Silva-Gomes, R, Savino, B, Gulic, T, Doni, A, Lonardi, S, Boutet, MA, Nerviani, A, Carriero, R, Molgora, M, Stravalaci, M, Morone, D, Shalova, IN, Lee, Y, Biswas, SK, Mantovani, G, Sironi, M, Pitzalis, C, Vermi, W, Bottazzi, B, Mantovani, A, Locati, M

Publikováno v: Nat Immunol

The tetraspan surface molecule MS4A4A is selectively expressed by cells of the monocyte-macrophage lineage(s), being induced during monocyte-to-macrophage differentiation, but not in dendritic cells. In vitro, MS4A4A is upregulated in macrophages by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a1dd590f8fd7b905f1a42dbdf2812e75
https://europepmc.org/articles/PMC7176488/

Comprehensive Characterization of Tissue Mineralization in an Ex Vivo Model.

Autor: Lesage C; Nantes Université, Univ Angers, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229., Guihard P; Nantes Université, Univ Angers, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229., De Fourmestraux C; Nantes Université, Univ Angers, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229., Gauthier O; Nantes Université, Univ Angers, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229., Weiss P; Nantes Université, Univ Angers, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229., Guicheux J; Nantes Université, Univ Angers, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229., Mieczkowska A; Nantes Université, Univ Angers, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229., Véziers J; Nantes Université, Univ Angers, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229., Charbonnier B; Nantes Université, Univ Angers, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229., Boutet MA; Nantes Université, Univ Angers, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229., Mabilleau G; Nantes Université, Univ Angers, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229; CHU Angers, Departement pathologie cellulaire et tissulaire; guillaume.mabilleau@univ-angers.fr.

Publikováno v: Journal of visualized experiments : JoVE [J Vis Exp] 2024 Sep 27 (211). Date of Electronic Publication: 2024 Sep 27.

Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis.

Autor: Nerviani A; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK., Boutet MA; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK.; Nantes Université, Oniris, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229, F-44000, Nantes, France., Ghirardi GM; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK., Goldmann K; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK., Sciacca E; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK., Rivellese F; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK., Pontarini E; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK., Prediletto E; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK., Abatecola F; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK., Caliste M; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK., Pagani S; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK., Mauro D; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK., Bellan M; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK.; Department of Rheumatology, University of Eastern Piedmont and Maggiore della Carita Hospital, Novara, Italy., Cubuk C; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK., Lau R; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK., Church SE; NanoString Technologies Inc, Seattle, WA, USA., Hudson BM; NanoString Technologies Inc, Seattle, WA, USA., Humby F; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK., Bombardieri M; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK., Lewis MJ; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK., Pitzalis C; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London & NIHR BRC Barts Health NHS Trust, London, UK. c.pitzalis@qmul.ac.uk.; Department of Biomedical Sciences, Humanitas University & IRCCS Humanitas Research Hospital, Milan, Italy. c.pitzalis@qmul.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2024 Mar 16; Vol. 15 (1), pp. 2398. Date of Electronic Publication: 2024 Mar 16.

Osteoarthritic chondrocytes undergo a glycolysis-related metabolic switch upon exposure to IL-1b or TNF.

Autor: Defois A; Nantes Université, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229, 44000, Nantes, France., Bon N; Nantes Université, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229, 44000, Nantes, France., Charpentier A; Nantes Université, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229, 44000, Nantes, France., Georget M; Nantes Université, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229, 44000, Nantes, France., Gaigeard N; Nantes Université, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229, 44000, Nantes, France., Blanchard F; Nantes Université, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229, 44000, Nantes, France., Hamel A; Nantes Université, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229, 44000, Nantes, France., Waast D; Nantes Université, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229, 44000, Nantes, France., Armengaud J; Département Médicaments Et Technologies Pour La Santé (DMTS), Université Paris-Saclay, CEA, INRAE, SPI, Bagnols-Sur-Cèze, 30200, France., Renoult O; Nantes Université, INSERM, CNRS, CRCI2NA, F-44000, Nantes, France., Pecqueur C; Nantes Université, INSERM, CNRS, CRCI2NA, F-44000, Nantes, France., Maugars Y; Nantes Université, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229, 44000, Nantes, France., Boutet MA; Nantes Université, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229, 44000, Nantes, France.; Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute and Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Guicheux J; Nantes Université, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229, 44000, Nantes, France. Jerome.guicheux@univ-nantes.fr., Vinatier C; Nantes Université, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229, 44000, Nantes, France. Claire.vinatier@univ-nantes.fr.

Publikováno v: Cell communication and signaling : CCS [Cell Commun Signal] 2023 Jun 14; Vol. 21 (1), pp. 137. Date of Electronic Publication: 2023 Jun 14.

Differential expression and regulation of MS4A family members in myeloid cells in physiological and pathological conditions.

Autor: Silva-Gomes R; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; ICBAS-Institute of Biomedical Sciences Abel Salazar, University of Porto, Porto, Portugal.; Instituto de Investigação e Inovação em Saúde and Instituto Nacional de Engenharia Biomédica, Universidade do Porto, Porto, Portugal., Mapelli SN; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Boutet MA; Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute and Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Regenerative Medicine and Skeleton, RMeS, Inserm UMR 1229, Oniris, CHU Nantes, Université de Nantes, Nantes, France., Mattiola I; Laboratory of Innate Immunity, Department of Microbiology, Infectious Diseases and Immunology, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.; Berlin Institute of Health (BIH), Berlin, Germany.; Mucosal and Developmental Immunology, Berlin, Germany., Sironi M; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Grizzi F; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Colombo F; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Supino D; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Carnevale S; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Pasqualini F; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Stravalaci M; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Porte R; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Infinity, Université Toulouse, CNRS, Inserm, UPS, Toulouse, France., Gianatti A; Unit of Pathology, Azienda Ospedaliera Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy., Pitzalis C; Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute and Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Locati M; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Medical Biotechnologies and Translational Medicine, University of Milan, Milan, Italy., Oliveira MJ; ICBAS-Institute of Biomedical Sciences Abel Salazar, University of Porto, Porto, Portugal.; Instituto de Investigação e Inovação em Saúde and Instituto Nacional de Engenharia Biomédica, Universidade do Porto, Porto, Portugal.; Department of Pathology and Oncology, Faculty of Medicine, University of Porto, Porto, Portugal., Bottazzi B; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Mantovani A; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute and Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

Publikováno v: Journal of leukocyte biology [J Leukoc Biol] 2022 Apr; Vol. 111 (4), pp. 817-836. Date of Electronic Publication: 2021 Aug 04.