Výsledky vyhledávání - "Bountra Chas"

Akademický článek

Use of the novel contact heat evoked potential stimulator (CHEPS) for the assessment of small fibre neuropathy: correlations with skin flare responses and intra-epidermal nerve fibre counts

Autor: Chizh Boris A, Misra V Peter, Roberts Katherine M, Facer Paul, Atherton Duncan D, Bountra Chas, Anand Praveen

Publikováno v: BMC Neurology, Vol 7, Iss 1, p 21 (2007)

Abstract Background The Contact Heat Evoked Potential Stimulator (CHEPS) rapidly stimulates cutaneous small nerve fibres, and resulting evoked potentials can be recorded from the scalp. We have studied patients with symptoms of sensory neuropathy and

Externí odkaz: https://doaj.org/article/248761d3485548ddae8a53660b86ad83

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Akademický článek

Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy

Autor: Bountra Chas, Chessell Iain P, Benham Christopher D, Smith Graham D, Casula Maria A, Facer Paul, Sinisi Marco, Birch Rolfe, Anand Praveen

Publikováno v: BMC Neurology, Vol 7, Iss 1, p 11 (2007)

Abstract Background Transient receptor potential (TRP) receptors expressed by primary sensory neurons mediate thermosensitivity, and may play a role in sensory pathophysiology. We previously reported that human dorsal root ganglion (DRG) sensory neur

Externí odkaz: https://doaj.org/article/bde69d7d11c843238df06263d2f4c896

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Akademický článek

Pain during ice water test distinguishes clinical bladder hypersensitivity from overactivity disorders

Autor: Bountra Chas, Chessell Iain P, Waters Janet, Mukerji Gaurav, Agarwal Sanjiv K, Anand Praveen

Publikováno v: BMC Urology, Vol 6, Iss 1, p 31 (2006)

Abstract Background The Bladder cooling reflex (BCR) i.e. uninhibited detrusor contractions evoked by intravesical instillation of cold saline, is a segmental reflex believed to be triggered by menthol sensitive cold receptors in the bladder wall, wi

Externí odkaz: https://doaj.org/article/086b6d99298144dca32192f623a8aa92

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Akademický článek

COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord

Autor: Bountra Chas, Naylor Alan, Chessell Iain P, Durrenberger Pascal, Facer Paul, Yiangou Yiangos, Banati Richard R, Anand Praveen

Publikováno v: BMC Neurology, Vol 6, Iss 1, p 12 (2006)

Abstract Background While multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS) are primarily inflammatory and degenerative disorders respectively, there is increasing evidence for shared cellular mechanisms that may affect disease progress

Externí odkaz: https://doaj.org/article/937fc2484db3452789fffe9ee0580e14

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Akademický článek

Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations

Autor: Benham Christopher D, Smith Graham D, Selmer Inger S, Corcoran Stacey L, Yiangou Yiangos, Mukerji Gaurav, Bountra Chas, Agarwal Sanjiv K, Anand Praveen

Publikováno v: BMC Urology, Vol 6, Iss 1, p 6 (2006)

Abstract Background The recent identification of the cold-menthol sensory receptor (TRPM8; CMR1), provides us with an opportunity to advance our understanding of its role in the pathophysiology of bladder dysfunction, and its potential mediation of t

Externí odkaz: https://doaj.org/article/23f4e08845fb4fb2a09e7d63c588e3f6

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Akademický článek

Increased capsaicin receptor TRPV1 in skin nerve fibres and related vanilloid receptors TRPV3 and TRPV4 in keratinocytes in human breast pain

Autor: Facer Paul, Holdcroft Anita, Wan Elaine, Gopinath Preethi, Davis John B, Smith Graham D, Bountra Chas, Anand Praveen

Publikováno v: BMC Women's Health, Vol 5, Iss 1, p 2 (2005)

Abstract Background Breast pain and tenderness affects 70% of women at some time. These symptoms have been attributed to stretching of the nerves with increase in breast size, but tissue mechanisms are poorly understood. Methods Eighteen patients (n

Externí odkaz: https://doaj.org/article/fd67728e9d06464c918d8c8b8ae92e70

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