Dual neutrophil subsets exacerbate or suppress inflammation in tuberculosis via IL-1β or PD-L1.

Autor: Doz-Deblauwe, Emilie, Bounab, Badreddine, Carreras, Florence, Fahel, Julia S., Oliveira, Sergio C., Lamkanfi, Mohamed, Le Vern, Yves, Germon, Pierre, Pichon, Julien, Kempf, Florent, Paget, Christophe, Remot, Aude, Winter, Nathalie

Publikováno v: Life Science Alliance; Jul2024, Vol. 7 Issue 7, p1-16, 16p, 7 Graphs

STING-dependent sensing of self-DNA drives silica-induced lung inflammation

Autor: Benmerzoug, Sulayman, Rose, Stéphanie, Bounab, Badreddine, Gosset, David, Duneau, Laure, Chenuet, Pauline, Mollet, Lucile, Le Bert, Marc, Lambers, Christopher, Geleff, Silvana, Roth, Michael, Fauconnier, Louis, Sedda, Delphine, Carvalho, Clarisse, Perche, Olivier, Laurenceau, David, Ryffel, Bernhard, Apetoh, Lionel, Kiziltunc, Ahmet, Uslu, Hakan, Albez, Fadime Sultan, Akgun, Metin, Togbe, Dieudonnée, Quesniaux, Valerie F. J.

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.5226. ⟨10.1038/s41467-018-07425-1⟩
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)

Silica particles induce lung inflammation and fibrosis. Here we show that stimulator of interferon genes (STING) is essential for silica-induced lung inflammation. In mice, silica induces lung cell death and self-dsDNA release in the bronchoalveolar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::de8143832ad19b42ef1b549fb25c5575
https://pubmed.ncbi.nlm.nih.gov/30523277

Sterile Lung Inflammation Induced by Silica Exacerbates Mycobacterium tuberculosisInfection via STING-Dependent Type 2 Immunity

Autor: Benmerzoug, Sulayman, Bounab, Badreddine, Rose, Stéphanie, Gosset, David, Biet, Franck, Cochard, Thierry, Xavier, Aurore, Rouxel, Nathalie, Fauconnier, Louis, Horsnell, William G.C., Ryffel, Bernhard, Togbe, Dieudonnee, Quesniaux, Valerie F.J.

Publikováno v: Cell Reports; May 2019, Vol. 27 Issue: 9 p2649-2664.e5