Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Boun L Thai"'
Autor:
Charles B. Trelford, Gianni M. Di Guglielmo, Eddie Chan, Boun L. Thai, Raiane Viana, Elio A. Cino, Iaci N. Soares
Publikováno v:
Pharmacological reports : PR. 72(3)
The M2 isoform of the glycolytic enzyme pyruvate kinase (PKM2) is one of the key components in the Warburg effect, and an important regulator of cancer cell metabolism. Elevated PKM2 expression is a hallmark of numerous tumor types, making it a promi
Publikováno v:
Molecular and Cellular Biology. 33:874-886
Epithelial-to-mesenchymal transition (EMT) is controlled by cellular signaling pathways that trigger the loss of cell-cell adhesion and lead to the restructuring of the cell cytoskeleton. Transforming growth factor β (TGF-β) has been shown to regul
Autor:
Boun L Thai, Serge Y. Fuchs, Yuval Shaked, Jane Lee, Yaacov Ben-David, Robert S. Kerbel, Brian J Pak, Ze'ev Ronai
Publikováno v:
Oncogene. 23:30-38
While melanomas are resistant to the cytotoxic effects of radiotherapy, little is known about the molecular mechanisms underlying this intrinsic resistance. Here, we describe the utilization of retroviral insertional mutagenesis to facilitate the ana