Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Bouman, L. N."'
Publikováno v:
Circulation, 101(22), 2639-2644. Lippincott Williams and Wilkins
BACKGROUND: The ionic mechanism underlying the transient inward current (I(ti)), the current responsible for delayed afterdepolarizations (DADs), appears to be different in ventricular myocytes and Purkinje fibers. In ventricular myocytes, I(ti) was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::f29314719ef56d4e78baa6b6b941914e
https://pure.amc.nl/en/publications/calciumactivated-cl-current-contributes-to-delayed-afterdepolarizations-in-single-purkinje-and-ventricular-myocytes(23cec94a-b806-4d03-9cb5-7d60f4ce3558).html
https://pure.amc.nl/en/publications/calciumactivated-cl-current-contributes-to-delayed-afterdepolarizations-in-single-purkinje-and-ventricular-myocytes(23cec94a-b806-4d03-9cb5-7d60f4ce3558).html
Autor:
Verkerk, A. O., Veldkamp, M. W., Abbate, F., Antoons, G., Bouman, L. N., Ravesloot, J. H., van Ginneken, A. C.
Publikováno v:
American journal of physiology, 277(4 Part 2), H1299-H1310. American Physiological Society
Membrane potentials and currents of isolated sheep Purkinje and ventricular cells were compared using patch-clamp and microelectrode techniques. In approximately 50% of Purkinje cells, we observed action potentials that showed a prominent phase 1 rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::8adeb9a7ac719bfe8dcefc740685a9f6
https://pure.amc.nl/en/publications/two-types-of-action-potential-configuration-in-single-cardiac-purkinje-cells-of-sheep(e9907af5-89b0-4ed2-a1a7-e8c39fa332f9).html
https://pure.amc.nl/en/publications/two-types-of-action-potential-configuration-in-single-cardiac-purkinje-cells-of-sheep(e9907af5-89b0-4ed2-a1a7-e8c39fa332f9).html
Publikováno v:
American journal of physiology, 276(3 Part 2), H1064-H1077. American Physiological Society
The role of L-type calcium current (ICa,L) in impulse generation was studied in single sinoatrial nodal myocytes of the rabbit, with the use of the amphotericin-perforated patch-clamp technique. Nifedipine, at a concentration of 5 microM, was used to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::0fad8fc3663fdeb492854492241122e2
https://pure.amc.nl/en/publications/contribution-of-ltype-ca2-current-to-electrical-activity-in-sinoatrial-nodal-myocytes-of-rabbits(ac658c0c-8569-40e2-aa56-d6097fec5553).html
https://pure.amc.nl/en/publications/contribution-of-ltype-ca2-current-to-electrical-activity-in-sinoatrial-nodal-myocytes-of-rabbits(ac658c0c-8569-40e2-aa56-d6097fec5553).html
Autor:
Wilders, R., Verheijck, E. E., Joyner, R. W., Golod, D. A., Kumar, R., van Ginneken, A. C., Bouman, L. N., Jongsma, H. J.
Publikováno v:
Circulation, 99(12), 1623-1629. Lippincott Williams and Wilkins
BACKGROUND: Acute ischemia often occurs in cardiac tissue that has prior injury, resulting in spatially inhomogeneous distributions of membrane properties and intercellular coupling. Changes in action potential conduction with ischemia, which can be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::0ebd6150e828f05a4b542200407e0a39
https://pure.amc.nl/en/publications/effects-of-ischemia-on-discontinuous-action-potential-conduction-in-hybrid-pairs-of-ventricular-cells(fc15177f-c69d-4381-9271-9d2b3eb4cc8b).html
https://pure.amc.nl/en/publications/effects-of-ischemia-on-discontinuous-action-potential-conduction-in-hybrid-pairs-of-ventricular-cells(fc15177f-c69d-4381-9271-9d2b3eb4cc8b).html
Autor:
Verheijck, E. E., Wessels, A., van Ginneken, A. C., Bourier, J., Markman, M. W., Vermeulen, J. L., de Bakker, J. M., Lamers, W. H., Opthof, T., Bouman, L. N.
Publikováno v:
Circulation, 97(16), 1623-1631. Lippincott Williams and Wilkins
BACKGROUND: In the sinoatrial node (SAN) the course of the action potential gradually changes from the primary pacemaker region toward the atrium. It is not known whether this gradient results from different intrinsic characteristics of the nodal cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::47ea1e8de27cf6bcfbfb42bbc8e7a96d
https://pure.amc.nl/en/publications/distribution-of-atrial-and-nodal-cells-within-the-rabbit-sinoatrial-node-models-of-sinoatrial-transition(8cfc3f73-f0b1-4467-b2f0-84159d0eff8b).html
https://pure.amc.nl/en/publications/distribution-of-atrial-and-nodal-cells-within-the-rabbit-sinoatrial-node-models-of-sinoatrial-transition(8cfc3f73-f0b1-4467-b2f0-84159d0eff8b).html
Publikováno v:
Circulation, 92(12), 3497-3504. Lippincott Williams and Wilkins
BACKGROUND: Previous studies have shown that in heart there are two kinetically distinct components of delayed rectifier current: a rapidly activating component (IKr) and a more slowly activating component (IKs). The presence of IKr and/or IKs appear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::964e6a2bc501cb7ddbc057bed4f626e7
https://pure.amc.nl/en/publications/delayed-rectifier-channels-in-human-ventricular-myocytes(a643efe0-a248-4cba-a5a1-2608b0cffc1a).html
https://pure.amc.nl/en/publications/delayed-rectifier-channels-in-human-ventricular-myocytes(a643efe0-a248-4cba-a5a1-2608b0cffc1a).html
Publikováno v:
Circulation research, 76(4), 607-615. Lippincott Williams and Wilkins
The role of the delayed rectifier current (IK) in impulse generation was studied in single sinoatrial nodal myocytes of the rabbit. We used the class III antiarrhythmic drug E-4031, which blocks IK in rabbit ventricular myocytes. In single sinoatrial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::5224d619bd66dfae0d2a322941c152e4
https://pure.amc.nl/en/publications/effects-of-delayed-rectifier-current-blockade-by-e4031-on-impulse-generation-in-single-sinoatrial-nodal-myocytes-of-the-rabbit(33220546-37c1-4a94-ac4a-6b9e3ae14888).html
https://pure.amc.nl/en/publications/effects-of-delayed-rectifier-current-blockade-by-e4031-on-impulse-generation-in-single-sinoatrial-nodal-myocytes-of-the-rabbit(33220546-37c1-4a94-ac4a-6b9e3ae14888).html
Publikováno v:
Circulation research, 72(4), 865-878. Lippincott Williams and Wilkins
In rabbit ventricular cells, the delayed rectifier current (IK) has not been extensively studied, and properties of single IK channels still need to be determined. In this study, we present data on a voltage-dependent channel in rabbit ventricular ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::b8ca1094702359e2ee3621eff0c499cc
https://pure.amc.nl/en/publications/single-delayed-rectifier-channels-in-the-membrane-of-rabbit-ventricular-myocytes(85b1f332-411a-4066-91b0-e76255258aae).html
https://pure.amc.nl/en/publications/single-delayed-rectifier-channels-in-the-membrane-of-rabbit-ventricular-myocytes(85b1f332-411a-4066-91b0-e76255258aae).html
Publikováno v:
Medische Fysiologie; 2008, pI-X, 10p
