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Autor:
Liddle J; Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, United Kingdom., Beneton V; GlaxoSmithKline, Paris, France., Benson M; Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, United Kingdom., Bingham R; Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, United Kingdom., Bouillot A; GlaxoSmithKline, Paris, France., Boullay AB; GlaxoSmithKline, Paris, France., Brook E; Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, United Kingdom., Cryan J; Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, United Kingdom., Denis A; GlaxoSmithKline, Paris, France., Edgar E; Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, United Kingdom., Ferrie A; Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, United Kingdom., Fouchet MH; GlaxoSmithKline, Paris, France., Grillot D; GlaxoSmithKline, Paris, France., Holmes DS; Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, United Kingdom., Howes A; Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, United Kingdom., Krysa G; GlaxoSmithKline, Paris, France., Laroze A; GlaxoSmithKline, Paris, France., Lennon M; Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, United Kingdom., McClure F; Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, United Kingdom., Moquette A; GlaxoSmithKline, Paris, France., Nicodeme E; GlaxoSmithKline, Paris, France., Santiago B; Discovery and Preclinical Development, GSK Dermatology Unit, Collegeville, Pennsylvania, USA., Santos L; Discovery and Preclinical Development, GSK Dermatology Unit, Collegeville, Pennsylvania, USA., Smith KJ; Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, United Kingdom., Thorpe JH; Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, United Kingdom., Thripp G; Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, United Kingdom., Trottet L; GlaxoSmithKline, Paris, France., Walker AL; Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, United Kingdom., Ward SA; Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, United Kingdom., Wang Y; Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche 1163, Laboratory of Genetic Skin Diseases, Imagine Institute, Paris, France., Wilson S; Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, United Kingdom., Pearce AC; Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, United Kingdom., Hovnanian A; Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche 1163, Laboratory of Genetic Skin Diseases, Imagine Institute, Paris, France; University of Paris, Paris, France; Department of Genetics, Necker hospital for sick children, Assistance Publique-Hôpitaux de Paris, Paris, France. Electronic address: alain.hovnanian@inserm.fr.
Publikováno v:
The Journal of investigative dermatology [J Invest Dermatol] 2021 Sep; Vol. 141 (9), pp. 2272-2279. Date of Electronic Publication: 2021 Mar 18.
Autor:
Deng H; Platform of Technology and Science, GlaxoSmithKline , 830 Winter Street, Waltham, Massachusetts 02451, United States., Zhou J; Platform of Technology and Science, GlaxoSmithKline , 830 Winter Street, Waltham, Massachusetts 02451, United States., Sundersingh F; Platform of Technology and Science, GlaxoSmithKline , 830 Winter Street, Waltham, Massachusetts 02451, United States., Messer JA; Platform of Technology and Science, GlaxoSmithKline , 830 Winter Street, Waltham, Massachusetts 02451, United States., Somers DO; Medicines Research Centre, GlaxoSmithKline , Gunnels Wood Road, Stevenage, Herts, SG1 2NY, U.K., Ajakane M; Centre de Recherche, GlaxoSmithKline , Les Ulis, 25,27 Avenue du Québec, 91140 Villebon sur Yvette, France., Arico-Muendel CC; Platform of Technology and Science, GlaxoSmithKline , 830 Winter Street, Waltham, Massachusetts 02451, United States., Beljean A; Medicines Research Centre, GlaxoSmithKline , Gunnels Wood Road, Stevenage, Herts, SG1 2NY, U.K., Belyanskaya SL; Platform of Technology and Science, GlaxoSmithKline , 830 Winter Street, Waltham, Massachusetts 02451, United States., Bingham R; Medicines Research Centre, GlaxoSmithKline , Gunnels Wood Road, Stevenage, Herts, SG1 2NY, U.K., Blazensky E; Chemistry Department, Northeastern University , Boston, Massachusetts 02115, United States., Boullay AB; Centre de Recherche, GlaxoSmithKline , Les Ulis, 25,27 Avenue du Québec, 91140 Villebon sur Yvette, France., Boursier E; Centre de Recherche, GlaxoSmithKline , Les Ulis, 25,27 Avenue du Québec, 91140 Villebon sur Yvette, France., Chai J; Platform of Technology and Science, GlaxoSmithKline , 830 Winter Street, Waltham, Massachusetts 02451, United States., Carter P; Medicines Research Centre, GlaxoSmithKline , Gunnels Wood Road, Stevenage, Herts, SG1 2NY, U.K., Chung CW; Medicines Research Centre, GlaxoSmithKline , Gunnels Wood Road, Stevenage, Herts, SG1 2NY, U.K., Daugan A; Centre de Recherche, GlaxoSmithKline , Les Ulis, 25,27 Avenue du Québec, 91140 Villebon sur Yvette, France., Ding Y; Platform of Technology and Science, GlaxoSmithKline , 830 Winter Street, Waltham, Massachusetts 02451, United States., Herry K; Centre de Recherche, GlaxoSmithKline , Les Ulis, 25,27 Avenue du Québec, 91140 Villebon sur Yvette, France., Hobbs C; Medicines Research Centre, GlaxoSmithKline , Gunnels Wood Road, Stevenage, Herts, SG1 2NY, U.K., Humphries E; Chemistry Department, Northeastern University , Boston, Massachusetts 02115, United States., Kollmann C; Platform of Technology and Science, GlaxoSmithKline , 830 Winter Street, Waltham, Massachusetts 02451, United States., Nguyen VL; Centre de Recherche, GlaxoSmithKline , Les Ulis, 25,27 Avenue du Québec, 91140 Villebon sur Yvette, France., Nicodeme E; Centre de Recherche, GlaxoSmithKline , Les Ulis, 25,27 Avenue du Québec, 91140 Villebon sur Yvette, France., Smith SE; Medicines Research Centre, GlaxoSmithKline , Gunnels Wood Road, Stevenage, Herts, SG1 2NY, U.K., Dodic N; Centre de Recherche, GlaxoSmithKline , Les Ulis, 25,27 Avenue du Québec, 91140 Villebon sur Yvette, France., Ancellin N; Centre de Recherche, GlaxoSmithKline , Les Ulis, 25,27 Avenue du Québec, 91140 Villebon sur Yvette, France.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2016 Feb 08; Vol. 7 (4), pp. 379-84. Date of Electronic Publication: 2016 Feb 08 (Print Publication: 2016).
Autor:
Bertrand SM; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K.; Department of Pure and Applied Chemistry, University of Strathclyde , 295 Cathedral Street, Glasgow, G1 1XL, U.K., Ancellin N; Centre de Recherche, GlaxoSmithKline R&D, Les Ulis , 25, 27 Avenue du Québec, 91140 Villebon sur Yvette, France., Beaufils B; Centre de Recherche, GlaxoSmithKline R&D, Les Ulis , 25, 27 Avenue du Québec, 91140 Villebon sur Yvette, France., Bingham RP; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Borthwick JA; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K.; Department of Pure and Applied Chemistry, University of Strathclyde , 295 Cathedral Street, Glasgow, G1 1XL, U.K., Boullay AB; Centre de Recherche, GlaxoSmithKline R&D, Les Ulis , 25, 27 Avenue du Québec, 91140 Villebon sur Yvette, France., Boursier E; Centre de Recherche, GlaxoSmithKline R&D, Les Ulis , 25, 27 Avenue du Québec, 91140 Villebon sur Yvette, France., Carter PS; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Chung CW; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Churcher I; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Dodic N; Centre de Recherche, GlaxoSmithKline R&D, Les Ulis , 25, 27 Avenue du Québec, 91140 Villebon sur Yvette, France., Fouchet MH; Centre de Recherche, GlaxoSmithKline R&D, Les Ulis , 25, 27 Avenue du Québec, 91140 Villebon sur Yvette, France., Fournier C; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Francis PL; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Gummer LA; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Herry K; Centre de Recherche, GlaxoSmithKline R&D, Les Ulis , 25, 27 Avenue du Québec, 91140 Villebon sur Yvette, France., Hobbs A; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Hobbs CI; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Homes P; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Jamieson C; Department of Pure and Applied Chemistry, University of Strathclyde , 295 Cathedral Street, Glasgow, G1 1XL, U.K., Nicodeme E; Centre de Recherche, GlaxoSmithKline R&D, Les Ulis , 25, 27 Avenue du Québec, 91140 Villebon sur Yvette, France., Pickett SD; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Reid IH; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Simpson GL; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Sloan LA; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Smith SE; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Somers DO; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Spitzfaden C; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Suckling CJ; Department of Pure and Applied Chemistry, University of Strathclyde , 295 Cathedral Street, Glasgow, G1 1XL, U.K., Valko K; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Washio Y; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K., Young RJ; GlaxoSmithKline R&D, Medicines Research Centre , Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2015 Sep 24; Vol. 58 (18), pp. 7140-63. Date of Electronic Publication: 2015 Jul 02.
Autor:
Mirguet O; Lipid Metabolism Discovery Performance Unit, GlaxoSmithKline, Les Ulis Cedex, France. olivier.x.mirguet@gsk.com, Lamotte Y, Donche F, Toum J, Gellibert F, Bouillot A, Gosmini R, Nguyen VL, Delannée D, Seal J, Blandel F, Boullay AB, Boursier E, Martin S, Brusq JM, Krysa G, Riou A, Tellier R, Costaz A, Huet P, Dudit Y, Trottet L, Kirilovsky J, Nicodeme E
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2012 Apr 15; Vol. 22 (8), pp. 2963-7. Date of Electronic Publication: 2012 Feb 08.
Autor:
Chung CW; Molecular Discovery Research, GlaxoSmithKline R&D, Stevenage SG5 4HT, UK. Chun-Wa.H.Chung@gsk.com, Coste H, White JH, Mirguet O, Wilde J, Gosmini RL, Delves C, Magny SM, Woodward R, Hughes SA, Boursier EV, Flynn H, Bouillot AM, Bamborough P, Brusq JM, Gellibert FJ, Jones EJ, Riou AM, Homes P, Martin SL, Uings IJ, Toum J, Clement CA, Boullay AB, Grimley RL, Blandel FM, Prinjha RK, Lee K, Kirilovsky J, Nicodeme E
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2011 Jun 09; Vol. 54 (11), pp. 3827-38. Date of Electronic Publication: 2011 May 13.
Autor:
Colin S; Institut Pasteur de Lille, Département d'Athérosclérose, Unité 545, Lille, France., Bourguignon E, Boullay AB, Tousaint JJ, Huet S, Caira F, Staels B, Lestavel S, Lobaccaro JM, Delerive P
Publikováno v:
Endocrinology [Endocrinology] 2008 Oct; Vol. 149 (10), pp. 5128-35. Date of Electronic Publication: 2008 Jun 19.
Autor:
Fouchet MH; Department of Medicinal chemistry, Laboratoire GlaxoSmithKline, 25-27 Avenue du Québec, 91951 Les Ulis, France. marie-helene.fouchet@gsk.com, Donche F, Martin C, Bouillot A, Junot C, Boullay AB, Potvain F, Magny SD, Coste H, Walker M, Issandou M, Dodic N
Publikováno v:
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2008 Jun 01; Vol. 16 (11), pp. 6218-32. Date of Electronic Publication: 2008 Apr 18.
Autor:
Sierra ML; Department of Medicinal Chemistry, Laboratoire GlaxoSmithKline, Centre de Recherches, 25-27 avenue du Québec, 91951 Les Ulis, France, USA., Beneton V, Boullay AB, Boyer T, Brewster AG, Donche F, Forest MC, Fouchet MH, Gellibert FJ, Grillot DA, Lambert MH, Laroze A, Le Grumelec C, Linget JM, Montana VG, Nguyen VL, Nicodème E, Patel V, Penfornis A, Pineau O, Pohin D, Potvain F, Poulain G, Ruault CB, Saunders M, Toum J, Xu HE, Xu RX, Pianetti PM
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2007 Feb 22; Vol. 50 (4), pp. 685-95. Date of Electronic Publication: 2007 Jan 23.