Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Boulghourjian, A."'
Autor:
James R.W. Conway, Sean C. Warren, David Herrmann, Kendelle J. Murphy, Aurélie S. Cazet, Claire Vennin, Robert F. Shearer, Monica J. Killen, Astrid Magenau, Pauline Mélénec, Mark Pinese, Max Nobis, Anaiis Zaratzian, Alice Boulghourjian, Andrew M. Da Silva, Gonzalo del Monte-Nieto, Arne S.A. Adam, Richard P. Harvey, Jody J. Haigh, Yingxiao Wang, David R. Croucher, Owen J. Sansom, Marina Pajic, C. Elizabeth Caldon, Jennifer P. Morton, Paul Timpson
Publikováno v:
Cell Reports, Vol 23, Iss 11, Pp 3312-3326 (2018)
Summary: Application of advanced intravital imaging facilitates dynamic monitoring of pathway activity upon therapeutic inhibition. Here, we assess resistance to therapeutic inhibition of the PI3K pathway within the hypoxic microenvironment of pancre
Externí odkaz:
https://doaj.org/article/1dd7417190fc4a1586f84ed7e4b76935
A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts
Autor:
Max Nobis, David Herrmann, Sean C. Warren, Shereen Kadir, Wilfred Leung, Monica Killen, Astrid Magenau, David Stevenson, Morghan C. Lucas, Nadine Reischmann, Claire Vennin, James R.W. Conway, Alice Boulghourjian, Anaiis Zaratzian, Andrew M. Law, David Gallego-Ortega, Christopher J. Ormandy, Stacey N. Walters, Shane T. Grey, Jacqueline Bailey, Tatyana Chtanova, Julian M.W. Quinn, Paul A. Baldock, Peter I. Croucher, Juliane P. Schwarz, Agata Mrowinska, Lei Zhang, Herbert Herzog, Andrius Masedunskas, Edna C. Hardeman, Peter W. Gunning, Gonzalo del Monte-Nieto, Richard P. Harvey, Michael S. Samuel, Marina Pajic, Ewan J. McGhee, Anna-Karin E. Johnsson, Owen J. Sansom, Heidi C.E. Welch, Jennifer P. Morton, Douglas Strathdee, Kurt I. Anderson, Paul Timpson
Publikováno v:
Cell Reports, Vol 21, Iss 1, Pp 274-288 (2017)
The small GTPase RhoA is involved in a variety of fundamental processes in normal tissue. Spatiotemporal control of RhoA is thought to govern mechanosensing, growth, and motility of cells, while its deregulation is associated with disease development
Externí odkaz:
https://doaj.org/article/c83a8ae4b29e4df59cdaacb8bc5a5802
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
miR-139-5p overexpression significantly increased radiation sensitivity in 10 BC cell lines (A-I), and also sensitivity to ROS generator menadione (J).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af9f98530e31300fe125ac252f05b19
https://doi.org/10.1158/0008-5472.22417851
https://doi.org/10.1158/0008-5472.22417851
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
Supplementary Tables 1-6 Supp. Table 1: Clinicopathological characteristics of breast cancer patients whose tumours were profiled by miRNA expression microarrays to identify miRNAs associated with local relapse following radiotherapy. Supp. Table 2:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f951d92c4452a370f5c128e23ffa4fa
https://doi.org/10.1158/0008-5472.22417845
https://doi.org/10.1158/0008-5472.22417845
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
Radiotherapy is essential to the treatment of most solid tumors and acquired or innate resistance to this therapeutic modality is a major clinical problem. Here we show that miR-139-5p is a potent modulator of radiotherapy response in breast cancer v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c26eaaad942be250caced776fa8fee5
https://doi.org/10.1158/0008-5472.c.6509961
https://doi.org/10.1158/0008-5472.c.6509961
Autor:
Roger J. Daly, Mark J. Raftery, Robert L. Sutherland, Andrew V. Biankin, David J. Harrison, Peter Mullen, Dana Faratian, Alexander Swarbrick, Radhika Nair, Robert Shearer, Alice Boulghourjian, Danny Rickwood, David R. Croucher, Gillian M. Lehrbach, Ana Porta Cubas, Mark Pinese, Brigid C. Browne, Sandra A. O'Toole, Luxi Zhang, Falko Hochgräfe
Supplementary Table 5 from Tyrosine Phosphorylation Profiling Reveals the Signaling Network Characteristics of Basal Breast Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ed93c5c35b57d072df3efe7df87cfe
https://doi.org/10.1158/0008-5472.22385775.v1
https://doi.org/10.1158/0008-5472.22385775.v1
Autor:
Roger J. Daly, Mark J. Raftery, Robert L. Sutherland, Andrew V. Biankin, David J. Harrison, Peter Mullen, Dana Faratian, Alexander Swarbrick, Radhika Nair, Robert Shearer, Alice Boulghourjian, Danny Rickwood, David R. Croucher, Gillian M. Lehrbach, Ana Porta Cubas, Mark Pinese, Brigid C. Browne, Sandra A. O'Toole, Luxi Zhang, Falko Hochgräfe
Supplementary Table 1 from Tyrosine Phosphorylation Profiling Reveals the Signaling Network Characteristics of Basal Breast Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e12bef23464d38a958856abb19a3092
https://doi.org/10.1158/0008-5472.22385787
https://doi.org/10.1158/0008-5472.22385787
Autor:
Roger J. Daly, Mark J. Raftery, Robert L. Sutherland, Andrew V. Biankin, David J. Harrison, Peter Mullen, Dana Faratian, Alexander Swarbrick, Radhika Nair, Robert Shearer, Alice Boulghourjian, Danny Rickwood, David R. Croucher, Gillian M. Lehrbach, Ana Porta Cubas, Mark Pinese, Brigid C. Browne, Sandra A. O'Toole, Luxi Zhang, Falko Hochgräfe
Supplementary Table 3 from Tyrosine Phosphorylation Profiling Reveals the Signaling Network Characteristics of Basal Breast Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1251a9f7c3aac46cdbf8ef408d32d05a
https://doi.org/10.1158/0008-5472.22385781
https://doi.org/10.1158/0008-5472.22385781
Autor:
Roger J. Daly, Mark J. Raftery, Robert L. Sutherland, Andrew V. Biankin, David J. Harrison, Peter Mullen, Dana Faratian, Alexander Swarbrick, Radhika Nair, Robert Shearer, Alice Boulghourjian, Danny Rickwood, David R. Croucher, Gillian M. Lehrbach, Ana Porta Cubas, Mark Pinese, Brigid C. Browne, Sandra A. O'Toole, Luxi Zhang, Falko Hochgräfe
Supplementary Figure 1 from Tyrosine Phosphorylation Profiling Reveals the Signaling Network Characteristics of Basal Breast Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10c37da877fa6487aa5274a44d0e98ca
https://doi.org/10.1158/0008-5472.22385799.v1
https://doi.org/10.1158/0008-5472.22385799.v1
Autor:
Roger J. Daly, Mark J. Raftery, Robert L. Sutherland, Andrew V. Biankin, David J. Harrison, Peter Mullen, Dana Faratian, Alexander Swarbrick, Radhika Nair, Robert Shearer, Alice Boulghourjian, Danny Rickwood, David R. Croucher, Gillian M. Lehrbach, Ana Porta Cubas, Mark Pinese, Brigid C. Browne, Sandra A. O'Toole, Luxi Zhang, Falko Hochgräfe
Supplementary Figure Legends 1-3 from Tyrosine Phosphorylation Profiling Reveals the Signaling Network Characteristics of Basal Breast Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921494a8c0e30b4860bba3c0ac48c3ce
https://doi.org/10.1158/0008-5472.22385790
https://doi.org/10.1158/0008-5472.22385790