Design of TOLERANT: phase I/II safety assessment of intranodal administration of HSP70/mB29a self-peptide antigen-loaded autologous tolerogenic dendritic cells in patients with rheumatoid arthritis

Autor: Jacob M van Laar, Anna de Goede, Gerty Schreibelt, Arie Jan Stoppelenburg, I Jolanda M de Vries, Paco Welsing, Bouke Koeneman, Evert-Jan Breman, Laureen Lammers, Tjitske Duiveman-de Boer, Willem van Eden, Paul Leufkens, Femke Broere

Publikováno v: BMJ Open, Vol 14, Iss 9 (2024)

Introduction In rheumatoid arthritis (RA), immunosuppressive therapies may achieve symptomatic relief, but do not induce long-term, drug-free remission. Meanwhile, the lifelong use of immunosuppressive drugs confers increased risk for malignancy and

Externí odkaz: https://doaj.org/article/048d163ecbc2444592ca57a8e33b4efc

Value of C-reactive protein in differentiating viral from bacterial aetiologies in patients with non-malaria acute undifferentiated fever in tropical areas: a meta-analysis and individual patient data study

Autor: Twan Otten, Yoel Lubell, Thomas Althaus, Bouke Koeneman, André J. A. M. van der Ven, Quirijn de Mast

Publikováno v: Transactions of the Royal Society of Tropical Medicine and Hygiene, 115, 10, pp. 1130-1143
Transactions of the Royal Society of Tropical Medicine and Hygiene, 115, 1130-1143

C-reactive protein (CRP) is used to discriminate common bacterial and viral infections, but its utility in tropical settings remains unknown. We performed a meta-analysis of studies performed in Asia and Africa. First, mean CRP levels for specific tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae3e37d83d82480a8fd269a68e36423d
https://repository.ubn.ru.nl/handle/2066/238109