Zobrazeno 1 - 10 of 76 pro vyhledávání: '"Bouisset-Leonard M"'
1
Akademický článek
Development of a Pig Mammary Epithelial Cell Culture Model as a Non-Clinical Tool for Studying Epithelial Barrier-A Contribution from the IMI-ConcePTION Project.
Autor: Bernardini C; Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, 40064 Bologna, Italy., La Mantia D; Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, 40064 Bologna, Italy., Salaroli R; Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, 40064 Bologna, Italy., Zannoni A; Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, 40064 Bologna, Italy.; Health Sciences and Technologies-Interdepartmental Center for Industrial Research (CIRI-SDV), Alma Mater Studiorum-University of Bologna, 40126 Bologna, Italy., Nauwelaerts N; KU Leuven Drug Delivery and Disposition Lab, Department of Pharmaceutical and Pharmacological Sciences, O&N II Herestraat, 49 3000 Leuven, Belgium., Deferm N; KU Leuven Drug Delivery and Disposition Lab, Department of Pharmaceutical and Pharmacological Sciences, O&N II Herestraat, 49 3000 Leuven, Belgium., Ventrella D; Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, 40064 Bologna, Italy., Bacci ML; Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, 40064 Bologna, Italy., Sarli G; Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, 40064 Bologna, Italy., Bouisset-Leonard M; Novartis Pharma AG, Novartis Institutes for BioMedical Research, Werk Klybeck Postfach, CH-4002 Basel, Switzerland., Annaert P; KU Leuven Drug Delivery and Disposition Lab, Department of Pharmaceutical and Pharmacological Sciences, O&N II Herestraat, 49 3000 Leuven, Belgium., Forni M; Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, 40064 Bologna, Italy.; Health Sciences and Technologies-Interdepartmental Center for Industrial Research (CIRI-SDV), Alma Mater Studiorum-University of Bologna, 40126 Bologna, Italy.
Publikováno v: Animals : an open access journal from MDPI [Animals (Basel)] 2021 Jul 05; Vol. 11 (7). Date of Electronic Publication: 2021 Jul 05.
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2
Akademický článek
A comprehensive review on non-clinical methods to study transfer of medication into breast milk - A contribution from the ConcePTION project.
Autor: Nauwelaerts N; KU Leuven Drug Delivery and Disposition Lab, Department of Pharmaceutical and Pharmacological Sciences, O&N II Herestraat, 49 3000, Leuven, Belgium. Electronic address: nina.nauwelaerts@kuleuven.be., Deferm N; KU Leuven Drug Delivery and Disposition Lab, Department of Pharmaceutical and Pharmacological Sciences, O&N II Herestraat, 49 3000, Leuven, Belgium. Electronic address: neel.deferm@kuleuven.be., Smits A; Neonatal Intensive Care Unit, University Hospitals Leuven, UZ Leuven, Neonatology, Herestraat 49, 3000, Leuven, Belgium; Department of Development and Regeneration, KU Leuven, Belgium. Electronic address: anne.smits@uzleuven.be., Bernardini C; Department of Veterinary Medical Sciences, University of Bologna, 40064, Ozzano dell'Emilia, BO, Italy. Electronic address: chiara.bernardini5@unibo.it., Lammens B; BioNotus, Galileilaan 15, 2845, Niel, Belgium. Electronic address: bart.lammens@bionotus.com., Gandia P; Laboratoire de Pharmacocinétique et Toxicologie, Centre Hospitalier Universitaire de Toulouse, France. Electronic address: gandia_chu@yahoo.fr., Panchaud A; Service of Pharmacy Service, Lausanne University Hospital and University of Lausanne, Switzerland; Institute of Primary Health Care (BIHAM), University of Bern, Switzerland., Nordeng H; PharmacoEpidemiology and Drug Safety Research Group, Department of Pharmacy, University of Oslo, PB. 1068 Blindern, 0316, Oslo, Norway. Electronic address: h.m.e.nordeng@farmasi.uio.no., Bacci ML; Department of Veterinary Medical Sciences, University of Bologna, 40064, Ozzano dell'Emilia, BO, Italy. Electronic address: marialaura.bacci@unibo.it., Forni M; Department of Veterinary Medical Sciences, University of Bologna, 40064, Ozzano dell'Emilia, BO, Italy. Electronic address: monica.forni@unibo.it., Ventrella D; Department of Veterinary Medical Sciences, University of Bologna, 40064, Ozzano dell'Emilia, BO, Italy. Electronic address: domenico.ventrella2@unibo.it., Van Calsteren K; UZ Leuven, Gynaecology and Obstetrics, Herestraat 49, 3000, Leuven, Belgium. Electronic address: kristel.vancalsteren@uzleuven.be., DeLise A; Novartis Pharmaceuticals Corporation, Novartis Institutes for BioMedical Research, One Health Plaza, East Hanover, NJ, 07936, USA. Electronic address: anthony.delise@novartis.com., Huys I; KU Leuven, Department of Clinical Pharmacology and Pharmacotherapy, ON II Herestraat 49 - bus, 521 3000, Leuven, Belgium. Electronic address: isabelle.huys@kuleuven.be., Bouisset-Leonard M; Novartis Pharma AG, Novartis Institutes for BioMedical Research, Werk Klybeck Postfach, Basel, CH-4002, Switzerland. Electronic address: michele.bouisset-leonard@novartis.com., Allegaert K; Department of Development and Regeneration, KU Leuven, Belgium; KU Leuven, Department of Clinical Pharmacology and Pharmacotherapy, ON II Herestraat 49 - bus, 521 3000, Leuven, Belgium; Department of Clinical Pharmacy, Erasmus MC, Rotterdam, the Netherlands. Electronic address: karel.allegaert@uzleuven.be., Annaert P; KU Leuven Drug Delivery and Disposition Lab, Department of Pharmaceutical and Pharmacological Sciences, O&N II Herestraat, 49 3000, Leuven, Belgium. Electronic address: pieter.annaert@kuleuven.be.
Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Apr; Vol. 136, pp. 111038. Date of Electronic Publication: 2021 Jan 30.
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3
Akademický článek
Animal Models for In Vivo Lactation Studies: Anatomy, Physiology and Milk Compositions in the Most Used Non-Clinical Species: A Contribution from the ConcePTION Project.
Autor: Ventrella D; Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emlia, 40064 Bologna, Italy., Ashkenazi N; Global Research and Development, Teva Pharmaceutical Industries Ltd., Netanya 42504, Israel., Elmi A; Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emlia, 40064 Bologna, Italy., Allegaert K; Department of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium.; Department of Clinical Pharmacology and Pharmacotherapy, KU Leuven, 3000 Leuven, Belgium.; Department of Hospital Pharmacy, Erasmus MC, 3015 GD Rotterdam, The Netherlands., Aniballi C; Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emlia, 40064 Bologna, Italy., DeLise A; Novartis Pharmaceuticals Corporation, Novartis Institutes for BioMedical Research, East Hanover, NJ 07936, USA., Devine PJ; Novartis Pharmaceuticals Corporation, Novartis Institutes for BioMedical Research, Cambridge, MA 02139, USA., Smits A; Department of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium.; Neonatal Intensive Care Unit, University Hospital Leuven, 3000 Leuven, Belgium., Steiner L; Global Research and Development, Teva Pharmaceutical Industries Ltd., Netanya 42504, Israel., Forni M; Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emlia, 40064 Bologna, Italy., Bouisset-Leonard M; Novartis Pharma AG, Novartis Institutes for BioMedical Research, 4056 Basel, Switzerland., Bacci ML; Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emlia, 40064 Bologna, Italy.
Publikováno v: Animals : an open access journal from MDPI [Animals (Basel)] 2021 Mar 05; Vol. 11 (3). Date of Electronic Publication: 2021 Mar 05.
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4
Akademický článek
Development and Characterization of a Human Mammary Epithelial Cell Culture Model for the Blood–Milk Barrier—A Contribution from the ConcePTION Project.
Autor: La Mantia, Debora1 (AUTHOR) chiara.bernardini5@unibo.it, Nauwelaerts, Nina2 (AUTHOR) debora.lamantia2@unibo.it, Bernardini, Chiara1,3 (AUTHOR) augusta.zannoni@unibo.it, Zannoni, Augusta1,3 (AUTHOR) roberta.salaroli@unibo.it, Salaroli, Roberta1 (AUTHOR), Lin, Qi4 (AUTHOR) qi.lin@bionotus.com, Huys, Isabelle5 (AUTHOR) isabelle.huys@kuleuven.be, Annaert, Pieter2,4 (AUTHOR), Forni, Monica3,6 (AUTHOR)
Publikováno v: International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 21, p11454. 19p.
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5
Akademický článek
Insights into the Interaction Mechanisms of Peptide and Non-Peptide Inhibitors with MDM2 Using Gaussian-Accelerated Molecular Dynamics Simulations and Deep Learning.
Autor: Yang, Wanchun1 (AUTHOR) wangjian_lxy@sdjtu.edu.cn, Wang, Jian1 (AUTHOR), Zhao, Lu1 (AUTHOR), Chen, Jianzhong1 (AUTHOR) yangwch1982@126.com
Publikováno v: Molecules. Jul2024, Vol. 29 Issue 14, p3377. 22p.
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6
Akademický článek
XXVIII Annual Meeting of the Italian Association for Laboratory Animal Sciences †.
Autor: Galligioni, Viola1 (AUTHOR) v.galligioni@nin.knaw.nl, Campagnol, Marino2 (AUTHOR) marino.campagnol@gmail.com, Fuochi, Sara3 (AUTHOR) sara.fuochi@unibe.ch, Pagano, Valeria4 (AUTHOR) vpagano@fondazionerimed.com, Raspa, Marcello5 (AUTHOR) marcello.raspa@cnr.it, Sabbioni, Silvia6 (AUTHOR) sbs@unife.it, Zarattini, Paola7 (AUTHOR) sara.fuochi@unibe.ch
Publikováno v: Biology & Life Sciences Forum. 2024, Vol. 32, p1. 18p.
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7
Akademický článek
Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors.
Autor: Holzer P; Novartis Institutes for BioMedical Research , 4002 Basel, Switzerland., Masuya K; Novartis Institutes for BioMedical Research , 4002 Basel, Switzerland., Furet P; Novartis Institutes for BioMedical Research , 4002 Basel, Switzerland., Kallen J; Novartis Institutes for BioMedical Research , 4002 Basel, Switzerland., Valat-Stachyra T; Novartis Institutes for BioMedical Research , 4002 Basel, Switzerland., Ferretti S; Novartis Institutes for BioMedical Research , 4002 Basel, Switzerland., Berghausen J; Novartis Institutes for BioMedical Research , 4002 Basel, Switzerland., Bouisset-Leonard M; Novartis Institutes for BioMedical Research , 4002 Basel, Switzerland., Buschmann N; Novartis Institutes for BioMedical Research , 4002 Basel, Switzerland., Pissot-Soldermann C; Novartis Institutes for BioMedical Research , 4002 Basel, Switzerland., Rynn C; Novartis Institutes for BioMedical Research , 4002 Basel, Switzerland., Ruetz S; Novartis Institutes for BioMedical Research , 4002 Basel, Switzerland., Stutz S; Novartis Institutes for BioMedical Research , 4002 Basel, Switzerland., Chène P; Novartis Institutes for BioMedical Research , 4002 Basel, Switzerland., Jeay S; Novartis Institutes for BioMedical Research , 4002 Basel, Switzerland., Gessier F; Novartis Institutes for BioMedical Research , 4002 Basel, Switzerland.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2015 Aug 27; Vol. 58 (16), pp. 6348-58. Date of Electronic Publication: 2015 Aug 05.
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8
Akademický článek
Molecular Docking and Molecular Dynamics Studies Reveal the Anticancer Potential of Medicinal-Plant-Derived Lignans as MDM2-P53 Interaction Inhibitors.
Autor: Shoaib, Tagyedeen H.1 (AUTHOR) shoaibth37@hotmail.com, Abdelmoniem, Nihal1 (AUTHOR) nihal.khunaijir@gmail.com, Mukhtar, Rua M.1 (AUTHOR) ruamubarak1@gmail.com, Alqhtani, Amal Th.2 (AUTHOR) amtalqhtani@moh.gov.sa, Alalawi, Abdullah L.3 (AUTHOR) abdullahalalawi96@gmail.com, Alawaji, Razan4 (AUTHOR) razanalawaji@gmail.com, Althubyani, Mashael S.2 (AUTHOR) maalthubyani@moh.gov.sa, Mohamed, Shaimaa G. A.5 (AUTHOR) shaimaag1973@gmail.com, Mohamed, Gamal A.6 (AUTHOR) gahussein@kau.edu.sa, Ibrahim, Sabrin R. M.7,8 (AUTHOR) sabrin.ibrahim@bmc.edu.sa, Hussein, Hazem G. A.9 (AUTHOR) hazemgamal2005@gmail.com, Alzain, Abdulrahim A.1 (AUTHOR) sabrin.ibrahim@bmc.edu.sa
Publikováno v: Molecules. Sep2023, Vol. 28 Issue 18, p6665. 18p.
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9
Akademický článek
Therapeutic Strategies to Activate p53.
Autor: Aguilar, Angelo1 (AUTHOR) angeloag@med.umich.edu, Wang, Shaomeng1 (AUTHOR) angeloag@med.umich.edu
Publikováno v: Pharmaceuticals (14248247). Jan2023, Vol. 16 Issue 1, p24. 39p.
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10
Akademický článek
Design, synthesis, and molecular modeling of coumarin derivatives as MDM2 inhibitors targeting breast cancer.
Autor: Ahmed, Eman Y.1 (AUTHOR), Abdel Latif, Nehad A.1 (AUTHOR), Nasr, Tamer2 (AUTHOR), Awad, Hanem M.3 (AUTHOR), Abdelhafez, Omaima M.1 (AUTHOR) dromaima45@gmail.com
Publikováno v: Chemical Biology & Drug Design. Apr2022, Vol. 99 Issue 4, p609-619. 11p.
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