E-Cadherin-Deficient Epithelial Cells Are Sensitive to HDAC Inhibitors.

Autor: Decourtye-Espiard L; Cancer Genetics Laboratory, Centre for Translational Cancer Research (Te Aho Matatū), Department of Biochemistry, University of Otago, Dunedin 9016, New Zealand., Bougen-Zhukov N; Cancer Genetics Laboratory, Centre for Translational Cancer Research (Te Aho Matatū), Department of Biochemistry, University of Otago, Dunedin 9016, New Zealand., Godwin T; Cancer Genetics Laboratory, Centre for Translational Cancer Research (Te Aho Matatū), Department of Biochemistry, University of Otago, Dunedin 9016, New Zealand., Brew T; Cancer Genetics Laboratory, Centre for Translational Cancer Research (Te Aho Matatū), Department of Biochemistry, University of Otago, Dunedin 9016, New Zealand., Schulpen E; Cancer Genetics Laboratory, Centre for Translational Cancer Research (Te Aho Matatū), Department of Biochemistry, University of Otago, Dunedin 9016, New Zealand., Black MA; Cancer Genetics Laboratory, Centre for Translational Cancer Research (Te Aho Matatū), Department of Biochemistry, University of Otago, Dunedin 9016, New Zealand., Guilford P; Cancer Genetics Laboratory, Centre for Translational Cancer Research (Te Aho Matatū), Department of Biochemistry, University of Otago, Dunedin 9016, New Zealand.

Publikováno v: Cancers [Cancers (Basel)] 2021 Dec 30; Vol. 14 (1). Date of Electronic Publication: 2021 Dec 30.

Discovery of AL-GDa62 as a Potential Synthetic Lethal Lead for the Treatment of Gastric Cancer.

Autor: Luxenburger A; Ferrier Research Institute, Victoria University of Wellington, 69 Gracefield Rd, Lower Hutt 5040, New Zealand., Bougen-Zhukov N; Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, 710 Cumberland Street, Dunedin 9016, New Zealand., Fraser MG; Ferrier Research Institute, Victoria University of Wellington, 69 Gracefield Rd, Lower Hutt 5040, New Zealand., Beetham H; Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, 710 Cumberland Street, Dunedin 9016, New Zealand., Harris LD; Ferrier Research Institute, Victoria University of Wellington, 69 Gracefield Rd, Lower Hutt 5040, New Zealand., Schmidt D; Institute of Pharmacy, Christian-Albrechts-University of Kiel, Gutenbergstraße 76, D-24116 Kiel, Germany., Cameron SA; Ferrier Research Institute, Victoria University of Wellington, 69 Gracefield Rd, Lower Hutt 5040, New Zealand., Guilford PJ; Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, 710 Cumberland Street, Dunedin 9016, New Zealand., Evans GB; Ferrier Research Institute, Victoria University of Wellington, 69 Gracefield Rd, Lower Hutt 5040, New Zealand.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2021 Dec 23; Vol. 64 (24), pp. 18114-18142. Date of Electronic Publication: 2021 Dec 08.

Hereditary diffuse gastric cancer: updated clinical practice guidelines.

Autor: Blair VR; Department of Surgery, University of Auckland, Auckland, New Zealand; St Marks Breast Centre, Auckland, New Zealand., McLeod M; Kimihauora Health and Research Clinic, Mt Maunganui, New Zealand., Carneiro F; Instituto de Investigação e Inovação em Saúde & Institute of Molecular Pathology and Immunology of the University of Porto, Department of Pathology, University of Porto, Porto, Portugal., Coit DG; Memorial Sloan Kettering Cancer Center and Weill Cornell Medical School, New York, NY, USA., D'Addario JL; HereditaryDiffuseGastricCancer.org, Madison, WI, USA., van Dieren JM; Department of Gastrointestinal Oncology, The Netherlands Cancer Institute, Amsterdam, Netherlands., Harris KL; Brisbane, QLD, Australia., Hoogerbrugge N; Department of Human Genetics, Radboud University Medical Centre, Nijmegen, Netherlands., Oliveira C; Instituto de Investigação e Inovação em Saúde & Institute of Molecular Pathology and Immunology of the University of Porto, Department of Pathology, University of Porto, Porto, Portugal., van der Post RS; Department of Pathology, Radboud University Medical Centre, Nijmegen, Netherlands., Arnold J; New Zealand Familial Gastrointestinal Cancer Service, Auckland Hospital, Auckland, New Zealand., Benusiglio PR; Consultation d'Oncogénétique, Unité Fonctionnelle d'Oncogénétique, Département de Génétique, DMU BioGeM, Groupe Hospitalier Pitié-Salpêtrière, Sorbonne Université, Paris, France., Bisseling TM; Department of Gastroenterology, Radboud University Medical Centre, Nijmegen, Netherlands., Boussioutas A; Department of Medicine, Royal Melbourne Hospital and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, VIC, Australia., Cats A; Department of Gastrointestinal Oncology, The Netherlands Cancer Institute, Amsterdam, Netherlands., Charlton A; Department of Histopathology, Auckland Hospital, Auckland, New Zealand., Schreiber KEC; HereditaryDiffuseGastricCancer.org, Madison, WI, USA., Davis JL; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Pietro MD; Medical Research Council Cancer Unit, University of Cambridge, Cambridge, UK., Fitzgerald RC; Medical Research Council Cancer Unit, University of Cambridge, Cambridge, UK., Ford JM; Division of Oncology, Departments of Medicine and Genetics, Stanford University School of Medicine, Stanford, CA, USA., Gamet K; Genetic Health Service New Zealand Northern Hub, Auckland Hospital, Auckland, New Zealand., Gullo I; Instituto de Investigação e Inovação em Saúde & Institute of Molecular Pathology and Immunology of the University of Porto, Department of Pathology, University of Porto, Porto, Portugal., Hardwick RH; Cambridge University Hospitals National Health Service Foundation Trust, Cambridge, UK., Huntsman DG; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada., Kaurah P; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada; Hereditary Cancer Program, British Columbia Cancer, Vancouver, BC, Canada., Kupfer SS; Section of Gastroenterology, Nutrition and Hepatology, University of Chicago, Chicago, IL, USA., Latchford A; St Mark's Hospital, London, UK; Department of Cancer and Surgery, Imperial College, London, UK., Mansfield PF; University of Texas MD Anderson Cancer Center, Houston, TX, USA., Nakajima T; Department of Clinical Genetic Oncology, Cancer Institute Hospital, Tokyo, Japan., Parry S; New Zealand Familial Gastrointestinal Cancer Service, Auckland Hospital, Auckland, New Zealand., Rossaak J; Department of Surgery, Tauranga Hospital, Tauranga, New Zealand., Sugimura H; Department of Tumor Pathology, Hamamatsu University School of Medicine, Hamamatsu, Japan., Svrcek M; Sorbonne Université, Assistance Publique-Hôpitaux de Paris, Department of Pathology, Hôpital Saint-Antoine, Paris, France., Tischkowitz M; Department of Medical Genetics, National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, UK., Ushijima T; Division of Epigenomics, National Cancer Centre Research Institute, Tokyo, Japan., Yamada H; Department of Tumor Pathology, Hamamatsu University School of Medicine, Hamamatsu, Japan., Yang HK; Seoul National University Hospital, Seoul, South Korea., Claydon A; Department of Gastroenterology, Tauranga Hospital, Tauranga, New Zealand., Figueiredo J; Instituto de Investigação e Inovação em Saúde & Institute of Molecular Pathology and Immunology of the University of Porto, Department of Pathology, University of Porto, Porto, Portugal., Paringatai K; Te Tumu School of Māori, Pacific and Indigenous Studies, University of Otago, Dunedin, New Zealand., Seruca R; Instituto de Investigação e Inovação em Saúde & Institute of Molecular Pathology and Immunology of the University of Porto, Department of Pathology, University of Porto, Porto, Portugal., Bougen-Zhukov N; Cancer Genetics Laboratory, Te Aho Matatū, Department of Biochemistry, University of Otago, Dunedin, New Zealand., Brew T; Cancer Genetics Laboratory, Te Aho Matatū, Department of Biochemistry, University of Otago, Dunedin, New Zealand., Busija S; No Stomach for Cancer, Madison, WI, USA., Carneiro P; Instituto de Investigação e Inovação em Saúde & Institute of Molecular Pathology and Immunology of the University of Porto, Department of Pathology, University of Porto, Porto, Portugal., DeGregorio L; DeGregorio Family Foundation, New York, NY, USA., Fisher H; Brisbane, QLD, Australia., Gardner E; Kimihauora Health and Research Clinic, Mt Maunganui, New Zealand., Godwin TD; Cancer Genetics Laboratory, Te Aho Matatū, Department of Biochemistry, University of Otago, Dunedin, New Zealand., Holm KN; Department of Biochemistry and Molecular Medicine, University of California Davis School Of Medicine, Davis, CA, USA., Humar B; Laboratory of the Swiss Hepato-Pancreato-Biliary and Transplantation Centre, Department of Surgery, University Hospital Zürich, Zurich, Switzerland., Lintott CJ; Genetic Health Service New Zealand South Island Hub, Christchurch Hospital, Christchurch, New Zealand., Monroe EC; DeGregorio Family Foundation, New York, NY, USA., Muller MD; Mt Maunganui, New Zealand., Norero E; Esophagogastric Surgery Unit, Digestive Surgery Department, Hospital Dr Sotero del Rio, Pontificia Universidad Catolica de Chile, Santiago, Chile., Nouri Y; Cancer Genetics Laboratory, Te Aho Matatū, Department of Biochemistry, University of Otago, Dunedin, New Zealand., Paredes J; Instituto de Investigação e Inovação em Saúde & Institute of Molecular Pathology and Immunology of the University of Porto, Department of Pathology, University of Porto, Porto, Portugal., Sanches JM; Institute for Systems and Robotics, Instituto Superior Técnico, Lisbon, Portugal., Schulpen E; Cancer Genetics Laboratory, Te Aho Matatū, Department of Biochemistry, University of Otago, Dunedin, New Zealand., Ribeiro AS; Instituto de Investigação e Inovação em Saúde & Institute of Molecular Pathology and Immunology of the University of Porto, Department of Pathology, University of Porto, Porto, Portugal., Sporle A; Healthier Lives National Science Challenge, University of Otago, Dunedin, New Zealand., Whitworth J; Department of Medical Genetics, National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, UK., Zhang L; Department of Pathology and Laboratory Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA, USA., Reeve AE; Cancer Genetics Laboratory, Te Aho Matatū, Department of Biochemistry, University of Otago, Dunedin, New Zealand., Guilford P; Cancer Genetics Laboratory, Te Aho Matatū, Department of Biochemistry, University of Otago, Dunedin, New Zealand. Electronic address: parry.guilford@otago.ac.nz.

Publikováno v: The Lancet. Oncology [Lancet Oncol] 2020 Aug; Vol. 21 (8), pp. e386-e397.

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Toxoplasma gondii suppresses proliferation and migration of breast cancer cells by regulating their transcriptome.

Autor: Ye, Hengming^1,2 (AUTHOR), Zhou, Xiaotao² (AUTHOR), Zhu, Bike² (AUTHOR), Xiong, Tiantian² (AUTHOR), Huang, Weile² (AUTHOR), He, Feng² (AUTHOR), Li, Hui² (AUTHOR), Chen, Lihua³ (AUTHOR), Tang, Luying⁴ (AUTHOR), Ren, Zefang¹ (AUTHOR) renzef@mail.sysu.edu.cn

Publikováno v: Cancer Cell International. 4/23/2024, Vol. 24 Issue 1, p1-17. 17p.