Observation of nociceptive detection thresholds and cortical evoked potentials: Go/no-go versus two-interval forced choice

Autor: Boudewijn van den Berg, L. Vanwinsen, G. Pezzali, Jan R. Buitenweg

Publikováno v: Attention, perception & psychophysics, 84, 1359-1369. Springer

Pain scientists and clinicians search for objective measures of altered nociceptive processing to study and stratify chronic pain patients. Nociceptive processing can be studied by observing a combination of nociceptive detection thresholds and evoke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d981a42f877ada1bee01f2c89a056bb8
https://doi.org/10.3758/s13414-022-02484-5

Combining Psychophysical and EEG Biomarkers for Improved Observation of Altered Nociceptive Processing in Failed Back Surgery Syndrome

Autor: Boudewijn van den Berg, Tom Berfelo, Elisa M.H. Verhoeven, Imre P. Krabbenbos, Jan R. Buitenweg

Publikováno v: 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 174-177
STARTPAGE=174;ENDPAGE=177;TITLE=2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)

Diagnosis and stratification of chronic pain patients is difficult due to a lack of sensitive biomarkers for altered nociceptive and pain processing. Recent developments enabled to preferentially stimulate epidermal nerve fibers and simultaneously qu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1a7fb669b2e6a5f04430ba08af4729
https://doi.org/10.1109/embc46164.2021.9630906

Combined Psychophysical and Neurophysiological Tools for Mechanism-Based Observation of Impaired Nociceptive Processing

Autor: Boudewijn Van den Berg

Pain has an enormous impact on the lives of patients with chronic pain. Under healthy conditions, pain is caused by the activation of nociceptive Aδ- and C-fibers following actual or potential tissue damage. Patients with chronic neuropathic pain ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9219ad0cf2b619176fa086d85ceaefe
https://doi.org/10.3990/1.9789036553544

Novel surface electrode design for preferential activation of cutaneous nociceptors

Autor: Boudewijn Van den Berg, Aida Hejlskov Poulsen, Federico Arguissain, Jenny Tigerholm, Carsten Dahl Mørch, Jan R. Buitenweg, Ole Kæseler Andersen

Publikováno v: Poulsen, A H, van den Berg, B, Arguissain, F G, Tigerholm, J, Buitenweg, J R, Andersen, O K & Mørch, C D 2022, ' Novel surface electrode design for preferential activation of cutaneous nociceptors ', Journal of Neural Engineering, vol. 19, no. 1, 016010 . https://doi.org/10.1088/1741-2552/ac4950
Journal of neural engineering, 19(1):016010. IOP Publishing Ltd.

Objective. Small area electrodes enable preferential activation of nociceptive fibers. It is debated, however, whether co-activation of large fibers still occurs for the existing electrode designs. Moreover, existing electrodes are limited to low sti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef140beeac3e9278fddeb37c0ae2bad
https://doi.org/10.1088/1741-2552/ac4950

Exploring Nociceptive Detection Thresholds Combined with Evoked Potentials in Patients with Diabetes Mellitus

Autor: Tom Berfelo, Imre P. Krabbenbos, Boudewijn van Den Berg, Silvano R. Gefferie, Jan R. Buitenweg

Publikováno v: 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 2021, 1358-1361

There is a lack of diagnostic tools that can objectively measure small fiber neuropathy (SFN) in patients with diabetes mellitus (DM). Recently, nociceptive nerve function was observed by nociceptive detection thresholds (NDTs) and brain evoked poten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ab85b36740357ac9e301598876907d
https://doi.org/10.1109/embc46164.2021.9629620