Zobrazeno 1 - 10
of 268
pro vyhledávání: '"Boudewijn P F, Lelieveldt"'
Autor:
Boyd Kenkhuis, Antonios Somarakis, Lorraine de Haan, Oleh Dzyubachyk, Marieke E. IJsselsteijn, Noel F. C. C. de Miranda, Boudewijn P. F. Lelieveldt, Jouke Dijkstra, Willeke M. C. van Roon-Mom, Thomas Höllt, Louise van der Weerd
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-15 (2021)
Abstract Brain iron accumulation has been found to accelerate disease progression in amyloid-β(Aβ) positive Alzheimer patients, though the mechanism is still unknown. Microglia have been identified as key players in the disease pathogenesis, and ar
Externí odkaz:
https://doaj.org/article/3f4646cb0a074c658337fbd49da6c5aa
Autor:
Zheng Li, Frits Koning, Natasja L de Vries, Tamim Abdelaal, Boudewijn P F Lelieveldt, Noel F C C de Miranda, Hans Morreau, Dina Ruano, Alexander L Vahrmeijer, Bert A Bonsing, Thomas P Brouwer, Ricki T Krog, Arantza Fariña
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)
Background Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy in need of effective (immuno)therapeutic treatment strategies. For the optimal application and development of cancer immunotherapies, a comprehensive understanding of lo
Externí odkaz:
https://doaj.org/article/13685e07570f4ae2a64498103c5f4c6c
Autor:
Vincent van Unen, Laura F. Ouboter, Na Li, Mette Schreurs, Tamim Abdelaal, Yvonne Kooy-Winkelaar, Guillaume Beyrend, Thomas Höllt, P. W. Jeroen Maljaars, M. Luisa Mearin, Ahmed Mahfouz, Anne M. C. Witte, Cornelis H. M. Clemens, Sunje Abraham, Johanna C. Escher, Boudewijn P. F. Lelieveldt, M. Fernanda Pascutti, Andrea E. van der Meulen – de Jong, Frits Koning
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chronic intestinal inflammation underlies inflammatory bowel disease (IBD). Previous studies indicated alterations in the cellular immune system; however, it has been challenging to interrogate the role of all immune cell subsets simultaneously. Ther
Externí odkaz:
https://doaj.org/article/5773beda53f54f0c94e0e199ec7a70e8
Autor:
Hessam Sokooti, Sahar Yousefi, Mohamed S. Elmahdy, Boudewijn P. F. Lelieveldt, Marius Staring
Publikováno v:
IEEE Access, Vol 9, Pp 62008-62020 (2021)
In this paper we propose a supervised method to predict registration misalignment using convolutional neural networks (CNNs). This task is casted to a classification problem with multiple classes of misalignment: “correct” 0-3 mm, “poor” 3-6
Externí odkaz:
https://doaj.org/article/e8560d54a2914d2d8c52e9bea092e98b
Autor:
Nicola Pezzotti, Sahar Yousefi, Mohamed S. Elmahdy, Jeroen Hendrikus Fransiscus Van Gemert, Christophe Schuelke, Mariya Doneva, Tim Nielsen, Sergey Kastryulin, Boudewijn P. F. Lelieveldt, Matthias J. P. Van Osch, Elwin De Weerdt, Marius Staring
Publikováno v:
IEEE Access, Vol 8, Pp 204825-204838 (2020)
Adaptive intelligence aims at empowering machine learning techniques with the additional use of domain knowledge. In this work, we present the application of adaptive intelligence to accelerate MR acquisition. Starting from undersampled k-space data,
Externí odkaz:
https://doaj.org/article/723dd39f480f476b9cf7a6eac71a4db7
Autor:
Rahil Shahzad, Arun Shankar, Raquel Amier, Robin Nijveldt, Jos J. M. Westenberg, Albert de Roos, Boudewijn P. F. Lelieveldt, Rob J. van der Geest, on behalf of the Heart Brain Connection study group
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 21, Iss 1, Pp 1-14 (2019)
Abstract Background Aortic pulse wave velocity (PWV) is an indicator of aortic stiffness and is used as a predictor of adverse cardiovascular events. PWV can be non-invasively assessed using magnetic resonance imaging (MRI). PWV computation requires
Externí odkaz:
https://doaj.org/article/5161ba9d6626466195a6facafa2241b7
Autor:
Sjoerd M. H. Huisman, Ahmed Mahfouz, Nematollah K. Batmanghelich, Boudewijn P. F. Lelieveldt, Marcel J. T. Reinders, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Brain Informatics, Vol 5, Iss 2, Pp 1-10 (2018)
Abstract Imaging genetics deals with relationships between genetic variation and imaging variables, often in a disease context. The complex relationships between brain volumes and genetic variants have been explored with both dimension reduction meth
Externí odkaz:
https://doaj.org/article/f2b46be8d2cf404f90e914bee3a56a9c
Autor:
Vincent van Unen, Thomas Höllt, Nicola Pezzotti, Na Li, Marcel J. T. Reinders, Elmar Eisemann, Frits Koning, Anna Vilanova, Boudewijn P. F. Lelieveldt
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Single cell profiling yields high dimensional data of very large numbers of cells, posing challenges of visualization and analysis. Here the authors introduce a method for analysis of mass cytometry data that can handle very large datasets and allows
Externí odkaz:
https://doaj.org/article/e50b0012ac854b22b12f11d3326c67c4
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Objective: Our goal was to investigate the performance of an open source deformable image registration package, elastix, for fast and robust contour propagation in the context of online-adaptive intensity-modulated proton therapy (IMPT) for prostate
Externí odkaz:
https://doaj.org/article/5f4cfaca005b4c66b65804779eb89632
Autor:
Na Li, Vincent van Unen, Nannan Guo, Tamim Abdelaal, Antonios Somarakis, Jeroen Eggermont, Ahmed Mahfouz, Susana M. Chuva de Sousa Lopes, Boudewijn P. F. Lelieveldt, Frits Koning
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The human fetal immune system must protect the infant against the sudden exposure to a large variety of pathogens upon birth. While it is known that the fetal immune system develops in sequential waves, relatively little is known about the compositio
Externí odkaz:
https://doaj.org/article/a4176f1983424f9d88d52855430b0dbe