TCGA RNA-Seq and Tumor-Infiltrating Lymphocyte Imaging Data Reveal Cold Tumor Signatures of Invasive Ductal Carcinomas and Estrogen Receptor-Positive Human Breast Tumors.

Autor: Bou-Dargham MJ; Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306, USA., Sha L; Department of Statistics, Florida State University, Tallahassee, FL 32306, USA., Sarker DB; Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306, USA., Krakora-Compagno MZ; Institute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306, USA., Chen Z; Abbisko Therapeutics, Shanghai 200100, China., Zhang J; Department of Statistics, Florida State University, Tallahassee, FL 32306, USA., Sang QA; Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306, USA.; Institute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 May 27; Vol. 24 (11). Date of Electronic Publication: 2023 May 27.

TIPE polarity proteins are required for mucosal deployment of T lymphocytes and mucosal defense against bacterial infection.

Autor: Li M; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Stellar-Chance Laboratories, 422 Curie Blvd, Philadelphia, PA, 19104, USA. Mingyue.Li@pennmedicine.upenn.edu.; The Wistar Institute, Philadelphia, PA, 19104, USA. Mingyue.Li@pennmedicine.upenn.edu., Bou-Dargham MJ; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Stellar-Chance Laboratories, 422 Curie Blvd, Philadelphia, PA, 19104, USA., Yu J; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Stellar-Chance Laboratories, 422 Curie Blvd, Philadelphia, PA, 19104, USA., Etwebi Z; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Stellar-Chance Laboratories, 422 Curie Blvd, Philadelphia, PA, 19104, USA., Sun H; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Stellar-Chance Laboratories, 422 Curie Blvd, Philadelphia, PA, 19104, USA. hsun2@pennmedicine.upenn.edu., Chen YH; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Stellar-Chance Laboratories, 422 Curie Blvd, Philadelphia, PA, 19104, USA. yhc@pennmedicine.upenn.edu.; Faculty of Pharmaceutical Sciences, CAS Shenzhen Institute of Advanced Technology, Shenzhen, China. yhc@pennmedicine.upenn.edu.

Publikováno v: Molecular biomedicine [Mol Biomed] 2021 Dec 23; Vol. 2 (1), pp. 41. Date of Electronic Publication: 2021 Dec 23.

Advancements in Human Breast Cancer Targeted Therapy and Immunotherapy.

Autor: Bou-Dargham MJ; Department of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida, United States of America., Draughon S; Department of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida, United States of America., Cantrell V; Department of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida, United States of America., Khamis ZI; Department of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida, United States of America.; Department of Chemistry and Biochemistry, Faculty of Sciences-I, Lebanese University, Beirut, Lebanon., Sang QA; Department of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida, United States of America.; Institute of Molecular Biophysics, Florida State University, Tallahassee, Florida, United States of America.

Publikováno v: Journal of Cancer [J Cancer] 2021 Oct 11; Vol. 12 (23), pp. 6949-6963. Date of Electronic Publication: 2021 Oct 11 (Print Publication: 2021).

Secretome analysis reveals upregulated granzyme B in human androgen-repressed prostate cancer cells with mesenchymal and invasive phenotype.

Autor: Bou-Dargham MJ; Department of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida, United States of America., Sang QA; Department of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida, United States of America.; Institute of Molecular Biophysics, Florida State University, Tallahassee, Florida, United States of America.

Publikováno v: PloS one [PLoS One] 2020 Aug 07; Vol. 15 (8), pp. e0237222. Date of Electronic Publication: 2020 Aug 07 (Print Publication: 2020).

TNFAIP8 controls murine intestinal stem cell homeostasis and regeneration by regulating microbiome-induced Akt signaling.

Autor: Goldsmith JR; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. goldsj@pennmedicine.upenn.edu., Spitofsky N; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Zamani A; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Hood R; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Boggs A; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Li X; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Li M; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Reiner E; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; University of Pikeville-Kentucky School of Osteopathic Medicine, Pikeville, KY, 41501, USA., Ayyaz A; Centre for Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada., Etwebi Z; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Lu L; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Rivera Guzman J; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Department of Biology, University of Maryland Baltimore College, Baltimore, MD, 21250, USA., Bou-Dargham MJ; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Cathoupolis T; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Hakonarson H; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Sun H; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Wrana JL; Centre for Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Gonzalez MV; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Chen YH; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. yhc@pennmedicine.upenn.edu.

Publikováno v: Nature communications [Nat Commun] 2020 May 22; Vol. 11 (1), pp. 2591. Date of Electronic Publication: 2020 May 22.