Výsledky vyhledávání - "Botulinum Toxins/pharmacology"

Miniature synaptic events maintain dendritic spines via AMPA receptor activation

Autor: Scott M. Thompson, R A McKinney, Beat H. Gähwiler, R Dürr, Marco Capogna

Publikováno v: McKinney, R A, Capogna, M, Dürr, R, Gähwiler, B H & Thompson, S M 1999, ' Miniature synaptic events maintain dendritic spines via AMPA receptor activation ', Nature Neuroscience, vol. 2, no. 1, pp. 44-9 . https://doi.org/10.1038/4548

We investigated the influence of synaptically released glutamate on postsynaptic structure by comparing the effects of deafferentation, receptor antagonists and blockers of glutamate release in hippocampal slice cultures. CA1 pyramidal cell spine den

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7c936867831ae3ad8ff35338ebf319
https://doi.org/10.1038/4548

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Phosphorylation of SNAP-25 on serine-187 is induced by secretagogues in insulin-secreting cells, but is not correlated with insulin secretion

Autor: M.T. Costa, Carmen Gonelle-Gispert, Philippe A. Halban, Karin Sadoul, Masami Takahashi

Publikováno v: Biochemical Journal, Vol. 368, No Pt 1 (2002) pp. 223-232

The tSNARE (the target-membrane soluble NSF-attachment protein receptor, where NSF is N -ethylmaleimide-sensitive fusion protein) synaptosomal-associated protein of 25 kDa (SNAP-25) is implicated in regulated insulin secretion. In pheochromocytoma PC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ca08ce3f651b771507c44b488c6c95
https://pubmed.ncbi.nlm.nih.gov/12164783

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The golgi-associated COPI-coated buds and vesicles contain beta/gamma -actin

Autor: Teresa Babia, José Ballesta, Ana Luna, Holger Barth, Jaime Renau-Piqueras, Ferran Valderrama, José A. Martínez-Menárguez, Christine Chaponnier, Gustavo Egea

Publikováno v: Proceedings of the National Academy of Sciences, Vol. 97, No 4 (2000) pp. 1560-1565

It has been shown previously that the morphology and subcellular positioning of the Golgi complex is controlled by actin microfilaments. To further characterize the association between actin microfilaments and the Golgi complex, we have used the Clos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f966e10ecac1e6956f39d16fe95cb8
https://pubmed.ncbi.nlm.nih.gov/10677499

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SNAP-25a and -25b isoforms are both expressed in insulin-secreting cells and can function in insulin secretion

Autor: Philippe A. Halban, Stefan Catsicas, Michael Palmer, Heiner Niemann, Carmen Gonelle-Gispert, Karin Sadoul

Publikováno v: Biochemical Journal, Vol. 339 ( Pt 1) (1999) pp. 159-165

The tSNARE (the target-membrane soluble NSF-attachment protein receptor, where NSF is N-ethylmaleimide-sensitive fusion protein) synaptosomal-associated protein of 25 kDa (SNAP-25) is expressed in pancreatic B-cells and its cleavage by botulinum neur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e773b886f19ee157de842f4a094223fc
https://archive-ouverte.unige.ch/unige:8761

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SNAP-25 is expressed in islets of Langerhans and is involved in insulin release

Autor: Philippe A. Halban, Stefan Catsicas, C. Montecucco, Romano Regazzi, Claes B. Wollheim, Karin Sadoul, Ulrich Weller, Jochen Lang

Publikováno v: The Journal of Cell Biology, Vol. 128, No 6 (1995) pp. 1019-1028
The Journal of Cell Biology

SNAP-25 is known as a neuron specific molecule involved in the fusion of small synaptic vesicles with the presynaptic plasma membrane. By immunolocalization and Western blot analysis, it is now shown that SNAP-25 is also expressed in pancreatic endoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f4cb4442f914bc8481c082f8b04d32
http://hdl.handle.net/11577/2506752

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Elektronická kniha

Treatments From Toxins : The Therapeutic Potential of Clostridial Neurotoxins

Autor: Keith Alan Foster, Peter Hambleton, Clifford C. Shone

As little as two decades ago, deliberately injecting botulinum toxin into patients would have seemed foolhardy at best and criminal at worst. The increased clinical use of botulinum toxins has expanded the body of knowledge available on the structure

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Gelsolin-actin complex is target for ADP-ribosylation by Clostridium botulinum C2 toxin in intact human neutrophils

Autor: Micaella Wille, Ingo Just, Klaus Aktories, Christine Chaponnier

Publikováno v: European Journal of Pharmacology, Vol. 246, No 3 (1993) pp. 293-297

The gelsolin-actin complex was ADP-ribosylated by Clostridium botulinum C2 toxin and Clostridium perfringens iota toxin in lysates of human platelets and human neutrophils. When [32P]orthophosphate-labelled human neutrophils were treated with C. botu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb4a8f5f42e104a1f6edc014cbc64f07
https://archive-ouverte.unige.ch/unige:10928

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