Edible Seaweeds Extracts: Characterization and Functional Properties for Health Conditions.

Autor: Coelho M; Departamento de Engenharia Química, Instituto Superior de Engenharia de Lisboa (ISEL), Av. Conselheiro Emídio Navarro 1, 1959-007 Lisboa, Portugal., Duarte AP; Departamento de Engenharia Química, Instituto Superior de Engenharia de Lisboa (ISEL), Av. Conselheiro Emídio Navarro 1, 1959-007 Lisboa, Portugal., Pinto S; Departamento de Engenharia Química, Instituto Superior de Engenharia de Lisboa (ISEL), Av. Conselheiro Emídio Navarro 1, 1959-007 Lisboa, Portugal., Botelho HM; BioISI-Biosystems & Integrative Sciences Institute, Faculty of Sciences, Universidade de Lisboa, 1749-016 Lisboa, Portugal., Reis CP; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Professor Gama Pinto, 1649-003 Lisboa, Portugal.; Instituto de Biofísica e Engenharia Biomédica (IBEB), Faculdade de Ciências, Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal., Serralheiro ML; BioISI-Biosystems & Integrative Sciences Institute, Faculty of Sciences, Universidade de Lisboa, 1749-016 Lisboa, Portugal.; Departamento de Química e Bioquímica, Faculty of Sciences, Universidade de Lisboa, 1749-016 Lisboa, Portugal., Pacheco R; Departamento de Engenharia Química, Instituto Superior de Engenharia de Lisboa (ISEL), Av. Conselheiro Emídio Navarro 1, 1959-007 Lisboa, Portugal.; Centro de Química Estrutural-Institute of Molecular Sciences, Universidade de Lisboa, 1749-016 Lisboa, Portugal.

Publikováno v: Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2023 Mar 10; Vol. 12 (3). Date of Electronic Publication: 2023 Mar 10.

Absence of EPAC1 Signaling to Stabilize CFTR in Intestinal Organoids.

Autor: Ferreira JF; BioISI-Biosystems and Integrative Sciences Institute, Faculty of Sciences, University of Lisboa, Campo Grande, 1749-016 Lisboa, Portugal., Silva IAL; BioISI-Biosystems and Integrative Sciences Institute, Faculty of Sciences, University of Lisboa, Campo Grande, 1749-016 Lisboa, Portugal., Botelho HM; BioISI-Biosystems and Integrative Sciences Institute, Faculty of Sciences, University of Lisboa, Campo Grande, 1749-016 Lisboa, Portugal., Amaral MD; BioISI-Biosystems and Integrative Sciences Institute, Faculty of Sciences, University of Lisboa, Campo Grande, 1749-016 Lisboa, Portugal., Farinha CM; BioISI-Biosystems and Integrative Sciences Institute, Faculty of Sciences, University of Lisboa, Campo Grande, 1749-016 Lisboa, Portugal.

Publikováno v: Cells [Cells] 2022 Jul 25; Vol. 11 (15). Date of Electronic Publication: 2022 Jul 25.

Exploring YAP1-centered networks linking dysfunctional CFTR to epithelial-mesenchymal transition.

Autor: Quaresma MC; BioISI-Biosystems and Integrative Sciences Institute, Faculty of Sciences, University of Lisboa, Lisboa, Portugal., Botelho HM; BioISI-Biosystems and Integrative Sciences Institute, Faculty of Sciences, University of Lisboa, Lisboa, Portugal., Pankonien I; BioISI-Biosystems and Integrative Sciences Institute, Faculty of Sciences, University of Lisboa, Lisboa, Portugal., Rodrigues CS; BioISI-Biosystems and Integrative Sciences Institute, Faculty of Sciences, University of Lisboa, Lisboa, Portugal., Pinto MC; BioISI-Biosystems and Integrative Sciences Institute, Faculty of Sciences, University of Lisboa, Lisboa, Portugal., Costa PR; BioISI-Biosystems and Integrative Sciences Institute, Faculty of Sciences, University of Lisboa, Lisboa, Portugal., Duarte A; BioISI-Biosystems and Integrative Sciences Institute, Faculty of Sciences, University of Lisboa, Lisboa, Portugal., Amaral MD; BioISI-Biosystems and Integrative Sciences Institute, Faculty of Sciences, University of Lisboa, Lisboa, Portugal mdamaral@fc.ul.pt.

Publikováno v: Life science alliance [Life Sci Alliance] 2022 May 02; Vol. 5 (9). Date of Electronic Publication: 2022 May 02 (Print Publication: 2022).

CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system.

Autor: Lim SH; Donnelly Centre, University of Toronto, Toronto, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada., Snider J; Donnelly Centre, University of Toronto, Toronto, ON, Canada., Birimberg-Schwartz L; Programme in Translational Medicine, The Hospital for Sick Children, Toronto, ON, Canada.; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of Toronto, Toronto, ON, Canada., Ip W; Programme in Translational Medicine, The Hospital for Sick Children, Toronto, ON, Canada., Serralha JC; Faculty of Sciences, BioISI-Biosystems and Integrative Sciences Institute, University of Lisboa, Lisboa, Portugal.; Faculty of Life Sciences and Medicine, School of Bioscience Education, King's College London, London, UK., Botelho HM; Faculty of Sciences, BioISI-Biosystems and Integrative Sciences Institute, University of Lisboa, Lisboa, Portugal., Lopes-Pacheco M; Faculty of Sciences, BioISI-Biosystems and Integrative Sciences Institute, University of Lisboa, Lisboa, Portugal., Pinto MC; Faculty of Sciences, BioISI-Biosystems and Integrative Sciences Institute, University of Lisboa, Lisboa, Portugal., Moutaoufik MT; Department of Biochemistry, Research and Innovation Centre, University of Regina, Regina, SK, Canada., Zilocchi M; Department of Biochemistry, Research and Innovation Centre, University of Regina, Regina, SK, Canada., Laselva O; Department of Physiology, University of Toronto, Toronto, ON, Canada., Esmaeili M; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada., Kotlyar M; Osteoarthritis Research Program, Division of Orthopedic Surgery, Schroeder Arthritis Institute, University Health Network, Toronto, ON, Canada.; Data Science Discovery Centre for Chronic Diseases, Krembil Research Institute, University Health Network, Toronto, ON, Canada., Lyakisheva A; Donnelly Centre, University of Toronto, Toronto, ON, Canada., Tang P; Donnelly Centre, University of Toronto, Toronto, ON, Canada., López Vázquez L; Donnelly Centre, University of Toronto, Toronto, ON, Canada., Akula I; Donnelly Centre, University of Toronto, Toronto, ON, Canada., Aboualizadeh F; Donnelly Centre, University of Toronto, Toronto, ON, Canada., Wong V; Donnelly Centre, University of Toronto, Toronto, ON, Canada., Grozavu I; Donnelly Centre, University of Toronto, Toronto, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada., Opacak-Bernardi T; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia., Yao Z; Donnelly Centre, University of Toronto, Toronto, ON, Canada., Mendoza M; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Babu M; Department of Biochemistry, Research and Innovation Centre, University of Regina, Regina, SK, Canada., Jurisica I; Osteoarthritis Research Program, Division of Orthopedic Surgery, Schroeder Arthritis Institute, University Health Network, Toronto, ON, Canada.; Data Science Discovery Centre for Chronic Diseases, Krembil Research Institute, University Health Network, Toronto, ON, Canada.; Departments of Medical Biophysics and Computer Science, University of Toronto, Toronto, ON, Canada.; Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia., Gonska T; Programme in Translational Medicine, The Hospital for Sick Children, Toronto, ON, Canada.; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of Toronto, Toronto, ON, Canada., Bear CE; Department of Biochemistry, University of Toronto, Toronto, ON, Canada.; Department of Physiology, University of Toronto, Toronto, ON, Canada., Amaral MD; Faculty of Sciences, BioISI-Biosystems and Integrative Sciences Institute, University of Lisboa, Lisboa, Portugal., Stagljar I; Donnelly Centre, University of Toronto, Toronto, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.; Mediterranean Institute for Life Sciences, Split, Croatia.; School of Medicine, University of Split, Split, Croatia.

Publikováno v: Molecular systems biology [Mol Syst Biol] 2022 Feb; Vol. 18 (2), pp. e10629.

Organoids as a personalized medicine tool for ultra-rare mutations in cystic fibrosis: The case of S955P and 1717-2A>G.

Autor: Silva IAL; University of Lisboa, Faculty of Sciences, BioISI - Biosystems & Integrative Sciences Institute, Campo Grande, C8 bdg, 1749-016 Lisboa, Portugal., Doušová T; Department of Pediatrics, 2nd Faculty of Medicine, Charles University and University Hospital Motol, V Uvalu 84,Prague 5, 150 06 Prague, Czech Republic., Ramalho S; University of Lisboa, Faculty of Sciences, BioISI - Biosystems & Integrative Sciences Institute, Campo Grande, C8 bdg, 1749-016 Lisboa, Portugal., Centeio R; University of Lisboa, Faculty of Sciences, BioISI - Biosystems & Integrative Sciences Institute, Campo Grande, C8 bdg, 1749-016 Lisboa, Portugal., Clarke LA; University of Lisboa, Faculty of Sciences, BioISI - Biosystems & Integrative Sciences Institute, Campo Grande, C8 bdg, 1749-016 Lisboa, Portugal., Railean V; University of Lisboa, Faculty of Sciences, BioISI - Biosystems & Integrative Sciences Institute, Campo Grande, C8 bdg, 1749-016 Lisboa, Portugal., Botelho HM; University of Lisboa, Faculty of Sciences, BioISI - Biosystems & Integrative Sciences Institute, Campo Grande, C8 bdg, 1749-016 Lisboa, Portugal., Holubová A; Department of Biology and Medical Genetics, 2nd Faculty of Medicine, Charles University and University Hospital Motol, V Uvalu 84,Prague 5, 150 06 Prague, Czech Republic., Valášková I; Department of Medical Genetics, Masaryk University Brno and University Hospital Brno, Jihlavská 20, Brno 625 00, Czech Republic., Yeh JT; Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO, United States of America., Hwang TC; Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO, United States of America., Farinha CM; University of Lisboa, Faculty of Sciences, BioISI - Biosystems & Integrative Sciences Institute, Campo Grande, C8 bdg, 1749-016 Lisboa, Portugal., Kunzelmann K; Institut für Physiologie, Universität Regensburg, Universitätsstraße 31, D-93053 Regensburg, Germany., Amaral MD; University of Lisboa, Faculty of Sciences, BioISI - Biosystems & Integrative Sciences Institute, Campo Grande, C8 bdg, 1749-016 Lisboa, Portugal. Electronic address: mdamaral@fc.ul.pt.

Publikováno v: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2020 Nov 01; Vol. 1866 (11), pp. 165905. Date of Electronic Publication: 2020 Jul 28.