Single-pulse Gy-scale irradiation of biological cells at $10^{13}$ Gy/s average dose-rates from a laser-wakefield accelerator

Autor: McAnespie, C. A., Chaudhary, P., Streeter, M. J. V., Botchway, S. W., Bourgeois, N., Calvin, L., Cavanagh, N., Fleck, K., Jaroszynski, D., Kettle, B., Lupu, A. M., Mangles, S. P. D., McMahon, S. J., Mill, J., Needham, S. R., Rajeev, P. P., Sarma, J., Prise, K. M., Sarri, G.

We report on the first experimental characterization of a laser-wakefield accelerator able to deliver, in a single pulse, doses in excess of \unit[1]{Gy} on timescales of the order of a hundred femtoseconds, reaching unprecedented average dose-rates

Externí odkaz: http://arxiv.org/abs/2409.01717

The cell wall regulates dynamics and size of plasmamembrane nanodomains in Arabidopsis

Autor: McKenna, J. F., Rolfe, D. J., Webb, S. E. D., Tolmie, A. F., Botchway, S. W., Martin-Fernandez, M. L., Hawes, C., Runions, J.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2019 Jun . 116(26), 12857-12862.

Externí odkaz: https://www.jstor.org/stable/26744114

Induction and Rejoining of DNA Double-Strand Breaks in Chinese Hamster V79-4 Cells Irradiated with Characteristic Aluminum K and Copper L Ultrasoft X Rays

Autor: Botchway, S. W., Stevens, D. L., Hill, M. A., Jenner, T. J., O'Neill, P.

Publikováno v: Radiation Research, 1997 Oct 01. 148(4), 317-324.

Externí odkaz: https://www.jstor.org/stable/3579516

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DNA DSB Repair Dynamics following Irradiation with Laser-Driven Protons at Ultra-High Dose Rates

Autor: Hanton, F., Chaudhary, P., Doria, D., Gwynne, D., Maiorino, C., Scullion, C., Ahmed, H., Marshall, T., Naughton, K., Romagnani, L., Kar, S., Schettino, G., McKenna, P., Botchway, S., Symes, D. R., Rajeev, P. P., Prise, K. M., Borghesi, M.

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.4471. ⟨10.1038/s41598-019-40339-6⟩
Scientific Reports, 2019, 9 (1), pp.4471. ⟨10.1038/s41598-019-40339-6⟩
Hanton, F, Chaudhary, P, Doria, D, Gwynne, D, Maiorino, C, Scullion, C, Ahmed, H, Marshall, T, Naughton, K, Romagnani, L, Kar, S, Schettino, G, McKenna, P, Botchway, S W, Symes, D R, Rajeev, P P, Prise, K & Borghesi, M 2019, ' DNA DSB Repair Dynamics following Irradiation with Laser-Driven Protons at Ultra-High Dose Rates ', Scientific Reports, vol. 9, no. 1, 4471 . https://doi.org/10.1038/s41598-019-40339-6, https://doi.org/10.1038/s41598-019-40339-6
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)

International audience; Protontherapy has emerged as more effective in the treatment of certain tumors than photon based therapies. However, significant capital and operational costs make protontherapy less accessible. This has stimulated interest in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1e50f004549b8382327489239e05d31c
https://surrey.eprints-hosting.org/852776/