Výsledky vyhledávání

Akademický článek

Identification of Quinolinones as Antivirals against Venezuelan Equine Encephalitis Virus.

Autor: Haese NN; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, USA., May NA; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA., Taft-Benz S; Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA., Moukha-Chafiq O; Chemistry Department, Drug Discovery Division, Southern Research, Birmingham, Alabama, USA., Madadi N; Chemistry Department, Drug Discovery Division, Southern Research, Birmingham, Alabama, USA., Zhang S; Chemistry Department, Drug Discovery Division, Southern Research, Birmingham, Alabama, USA., Karyakarte SD; Chemistry Department, Drug Discovery Division, Southern Research, Birmingham, Alabama, USA., Rodzinak KJ; Chemistry Department, Drug Discovery Division, Southern Research, Birmingham, Alabama, USA., Nguyen TH; Chemistry Department, Drug Discovery Division, Southern Research, Birmingham, Alabama, USA., Denton M; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, USA., Streblow AD; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, USA., Towers NA; High-Throughput Screening Center, Drug Discovery Division, Southern Research, Birmingham, Alabama, USA., Rasmussen L; High-Throughput Screening Center, Drug Discovery Division, Southern Research, Birmingham, Alabama, USA., Bostwick RJ; High-Throughput Screening Center, Drug Discovery Division, Southern Research, Birmingham, Alabama, USA., Maddry JA; Chemistry Department, Drug Discovery Division, Southern Research, Birmingham, Alabama, USA., Ananthan S; Chemistry Department, Drug Discovery Division, Southern Research, Birmingham, Alabama, USA., Augelli-Szafran CE; Chemistry Department, Drug Discovery Division, Southern Research, Birmingham, Alabama, USA., Suto MJ; Chemistry Department, Drug Discovery Division, Southern Research, Birmingham, Alabama, USA., Sanders W; Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA., Moorman N; Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA., DeFilippis V; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, USA., Heise MT; Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA., Pathak AK; Chemistry Department, Drug Discovery Division, Southern Research, Birmingham, Alabama, USA., Streblow DN; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, USA., Morrison TE; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.

Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2021 Aug 17; Vol. 65 (9), pp. e0024421. Date of Electronic Publication: 2021 Aug 17.

Zobrazit plný text záznamu

Akademický článek

A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion.

Autor: Sharma J; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Medicine, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Microbiology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Du M; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Wong E; CFFT Lab, Cystic Fibrosis Foundation, Lexington, MA, USA., Mutyam V; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Medicine, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Li Y; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Medicine, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Chen J; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Medicine, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Wangen J; Department of Molecular Biology and Genetics and Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Thrasher K; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Fu L; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Peng N; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Medicine, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Tang L; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Medicine, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Liu K; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Mathew B; Southern Research, Birmingham, AL, USA., Bostwick RJ; Southern Research, Birmingham, AL, USA., Augelli-Szafran CE; Southern Research, Birmingham, AL, USA., Bihler H; CFFT Lab, Cystic Fibrosis Foundation, Lexington, MA, USA., Liang F; CFFT Lab, Cystic Fibrosis Foundation, Lexington, MA, USA., Mahiou J; CFFT Lab, Cystic Fibrosis Foundation, Lexington, MA, USA., Saltz J; CFFT Lab, Cystic Fibrosis Foundation, Lexington, MA, USA., Rab A; Department of Pediatrics, Emory University, Atlanta, Georgia., Hong J; Department of Pediatrics, Emory University, Atlanta, Georgia., Sorscher EJ; Department of Pediatrics, Emory University, Atlanta, Georgia., Mendenhall EM; Department of Biological Sciences, The University of Alabama in Huntsville, Huntsville, AL, USA., Coppola CJ; Department of Biological Sciences, The University of Alabama in Huntsville, Huntsville, AL, USA., Keeling KM; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Green R; Department of Molecular Biology and Genetics and Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Mense M; CFFT Lab, Cystic Fibrosis Foundation, Lexington, MA, USA., Suto MJ; Southern Research, Birmingham, AL, USA., Rowe SM; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Medicine, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.; Department of Pediatrics, University of Alabama at Birmingham (UAB), Birmingham, AL, USA., Bedwell DM; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham (UAB), Birmingham, AL, USA. dbedwell@uab.edu.; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham (UAB), Birmingham, AL, USA. dbedwell@uab.edu.

Publikováno v: Nature communications [Nat Commun] 2021 Jul 16; Vol. 12 (1), pp. 4358. Date of Electronic Publication: 2021 Jul 16.

Zobrazit plný text záznamu

Akademický článek

Discovery of a novel inhibitor of kinesin-like protein KIFC1.

Autor: Zhang W; Division of Drug Discovery, Southern Research Institute, Birmingham, AL 35205, U.S.A. wzhang@southernresearch.org., Zhai L; Division of Drug Discovery, Southern Research Institute, Birmingham, AL 35205, U.S.A., Wang Y; Division of Drug Discovery, Southern Research Institute, Birmingham, AL 35205, U.S.A., Boohaker RJ; Division of Drug Discovery, Southern Research Institute, Birmingham, AL 35205, U.S.A., Lu W; Division of Drug Discovery, Southern Research Institute, Birmingham, AL 35205, U.S.A., Gupta VV; Division of Drug Discovery, Southern Research Institute, Birmingham, AL 35205, U.S.A., Padmalayam I; Division of Drug Discovery, Southern Research Institute, Birmingham, AL 35205, U.S.A., Bostwick RJ; Division of Drug Discovery, Southern Research Institute, Birmingham, AL 35205, U.S.A., White EL; Division of Drug Discovery, Southern Research Institute, Birmingham, AL 35205, U.S.A., Ross LJ; Division of Drug Discovery, Southern Research Institute, Birmingham, AL 35205, U.S.A., Maddry J; Division of Drug Discovery, Southern Research Institute, Birmingham, AL 35205, U.S.A., Ananthan S; Division of Drug Discovery, Southern Research Institute, Birmingham, AL 35205, U.S.A., Augelli-Szafran CE; Division of Drug Discovery, Southern Research Institute, Birmingham, AL 35205, U.S.A., Suto MJ; Division of Drug Discovery, Southern Research Institute, Birmingham, AL 35205, U.S.A., Xu B; Division of Drug Discovery, Southern Research Institute, Birmingham, AL 35205, U.S.A., Li R; Division of Drug Discovery, Southern Research Institute, Birmingham, AL 35205, U.S.A., Li Y; Division of Drug Discovery, Southern Research Institute, Birmingham, AL 35205, U.S.A.

Publikováno v: The Biochemical journal [Biochem J] 2016 Apr 15; Vol. 473 (8), pp. 1027-35. Date of Electronic Publication: 2016 Feb 04.

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání