Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Bosiljka, Tasic"'
Autor:
Lina Marcela Carmona, Eric D. Thomas, Kimberly Smith, Bosiljka Tasic, Rui M. Costa, Anders Nelson
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 113993- (2024)
Summary: Corticospinal neurons (CSNs) synapse directly on spinal neurons, a diverse assortment of cells with unique structural and functional properties necessary for body movements. CSNs modulating forelimb behavior fractionate into caudal forelimb
Externí odkaz:
https://doaj.org/article/4f557b75d5b54115b4ac5455e6ecaf70
Autor:
Aixin Zhang, Lei Jin, Shenqin Yao, Makoto Matsuyama, Cindy TJ van Velthoven, Heather Anne Sullivan, Na Sun, Manolis Kellis, Bosiljka Tasic, Ian Wickersham, Xiaoyin Chen
Publikováno v:
eLife, Vol 12 (2024)
Mapping the connectivity of diverse neuronal types provides the foundation for understanding the structure and function of neural circuits. High-throughput and low-cost neuroanatomical techniques based on RNA barcode sequencing have the potential to
Externí odkaz:
https://doaj.org/article/112417cc5f8d47a4bcb098605ba0a640
Spatially resolved gene regulatory and disease-related vulnerability map of the adult Macaque cortex
Autor:
Ying Lei, Mengnan Cheng, Zihao Li, Zhenkun Zhuang, Liang Wu, Yunong sun, Lei Han, Zhihao Huang, Yuzhou Wang, Zifei Wang, Liqin Xu, Yue Yuan, Shang Liu, Taotao Pan, Jiarui Xie, Chuanyu Liu, Giacomo Volpe, Carl Ward, Yiwei Lai, Jiangshan Xu, Mingyue Wang, Hao Yu, Haixi Sun, Qichao Yu, Chunqing Wang, Chi Wai Wong, Wei Liu, Liangzhi Xu, Jingkuan Wei, Dandan Chen, Zhouchun Shang, Guibo Li, Kun Ma, Le Cheng, Fei Ling, Tao Tan, Kai Chen, Bosiljka Tasic, Michael Dean, Weizhi Ji, Huanming Yang, Ying Gu, Miguel A. Esteban, Yuxiang Li, Ao Chen, Yuyu Niu, Hongkui Zeng, Yong Hou, Longqi Liu, Shiping Liu, Xun Xu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Cell type epigenetic and topographic information of primate brain is lacking. Here, authors identified transcriptional regulatory network, gradient expression pattern and disease vulnerability at cell type level in PFC, M1 and V1 of monkey brain by s
Externí odkaz:
https://doaj.org/article/0ab4d766decf4a70b2a80a3a8ff72b4b
Autor:
Hayley A. Bounds, Masato Sadahiro, William D. Hendricks, Marta Gajowa, Karthika Gopakumar, Daniel Quintana, Bosiljka Tasic, Tanya L. Daigle, Hongkui Zeng, Ian Antón Oldenburg, Hillel Adesnik
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112909- (2023)
Summary: Determining which features of the neural code drive behavior requires the ability to simultaneously read out and write in neural activity patterns with high precision across many neurons. All-optical systems that combine two-photon calcium i
Externí odkaz:
https://doaj.org/article/776f38e9ab2849c7905a3de8ca6e4b0c
Autor:
Jeongbin Park, Wonyl Choi, Sebastian Tiesmeyer, Brian Long, Lars E. Borm, Emma Garren, Thuc Nghi Nguyen, Bosiljka Tasic, Simone Codeluppi, Tobias Graf, Matthias Schlesner, Oliver Stegle, Roland Eils, Naveed Ishaque
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Inaccurate cell segmentation has been the major problem for cell-type identification and tissue characterization of the in situ spatially resolved transcriptomics data. Here we show a robust cell segmentation-free computational framework (SSAM), for
Externí odkaz:
https://doaj.org/article/a175c0b017934a918d3257520493c81c
Autor:
Bastiaan van der Veen, Sampath K. T. Kapanaiah, Kasyoka Kilonzo, Peter Steele-Perkins, Martin M. Jendryka, Stefanie Schulz, Bosiljka Tasic, Zizhen Yao, Hongkui Zeng, Thomas Akam, Janet R. Nicholson, Birgit Liss, Wiebke Nissen, Anton Pekcec, Dennis Kätzel
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
In order to identify receptors that may serve as therapeutic targets in the treatment of impulse control disorders, van der Veen et al developed a systematic target discovery approach combining behavioural chemogenetics and gene expression analysis.
Externí odkaz:
https://doaj.org/article/cd48bdbae6944aca8dc5ad44ab6da068
Autor:
Trygve E Bakken, Cindy TJ van Velthoven, Vilas Menon, Rebecca D Hodge, Zizhen Yao, Thuc Nghi Nguyen, Lucas T Graybuck, Gregory D Horwitz, Darren Bertagnolli, Jeff Goldy, Anna Marie Yanny, Emma Garren, Sheana Parry, Tamara Casper, Soraya I Shehata, Eliza R Barkan, Aaron Szafer, Boaz P Levi, Nick Dee, Kimberly A Smith, Susan M Sunkin, Amy Bernard, John Phillips, Michael J Hawrylycz, Christof Koch, Gabe J Murphy, Ed Lein, Hongkui Zeng, Bosiljka Tasic
Publikováno v:
eLife, Vol 10 (2021)
Abundant evidence supports the presence of at least three distinct types of thalamocortical (TC) neurons in the primate dorsal lateral geniculate nucleus (dLGN) of the thalamus, the brain region that conveys visual information from the retina to the
Externí odkaz:
https://doaj.org/article/f603ae63e1374a53a6a3312be848bb59
Autor:
Brian R Lee, Agata Budzillo, Kristen Hadley, Jeremy A Miller, Tim Jarsky, Katherine Baker, DiJon Hill, Lisa Kim, Rusty Mann, Lindsay Ng, Aaron Oldre, Ram Rajanbabu, Jessica Trinh, Sara Vargas, Thomas Braun, Rachel A Dalley, Nathan W Gouwens, Brian E Kalmbach, Tae Kyung Kim, Kimberly A Smith, Gilberto Soler-Llavina, Staci Sorensen, Bosiljka Tasic, Jonathan T Ting, Ed Lein, Hongkui Zeng, Gabe J Murphy, Jim Berg
Publikováno v:
eLife, Vol 10 (2021)
The Patch-seq approach is a powerful variation of the patch-clamp technique that allows for the combined electrophysiological, morphological, and transcriptomic characterization of individual neurons. To generate Patch-seq datasets at scale, we ident
Externí odkaz:
https://doaj.org/article/34e4a68dbc504e52805f073d4e7d3060
Autor:
John K. Mich, Lucas T. Graybuck, Erik E. Hess, Joseph T. Mahoney, Yoshiko Kojima, Yi Ding, Saroja Somasundaram, Jeremy A. Miller, Brian E. Kalmbach, Cristina Radaelli, Bryan B. Gore, Natalie Weed, Victoria Omstead, Yemeserach Bishaw, Nadiya V. Shapovalova, Refugio A. Martinez, Olivia Fong, Shenqin Yao, Marty Mortrud, Peter Chong, Luke Loftus, Darren Bertagnolli, Jeff Goldy, Tamara Casper, Nick Dee, Ximena Opitz-Araya, Ali Cetin, Kimberly A. Smith, Ryder P. Gwinn, Charles Cobbs, Andrew L. Ko, Jeffrey G. Ojemann, C. Dirk Keene, Daniel L. Silbergeld, Susan M. Sunkin, Viviana Gradinaru, Gregory D. Horwitz, Hongkui Zeng, Bosiljka Tasic, Ed S. Lein, Jonathan T. Ting, Boaz P. Levi
Publikováno v:
Cell Reports, Vol 34, Iss 13, Pp 108754- (2021)
Summary: Viral genetic tools that target specific brain cell types could transform basic neuroscience and targeted gene therapy. Here, we use comparative open chromatin analysis to identify thousands of human-neocortical-subclass-specific putative en
Externí odkaz:
https://doaj.org/article/f3fbdff3e4964a89bce059657aed05d2
Autor:
Jeremy A Miller, Nathan W Gouwens, Bosiljka Tasic, Forrest Collman, Cindy TJ van Velthoven, Trygve E Bakken, Michael J Hawrylycz, Hongkui Zeng, Ed S Lein, Amy Bernard
Publikováno v:
eLife, Vol 9 (2020)
The advancement of single-cell RNA-sequencing technologies has led to an explosion of cell type definitions across multiple organs and organisms. While standards for data and metadata intake are arising, organization of cell types has largely been le
Externí odkaz:
https://doaj.org/article/38064ee71ff244a0840fe6e78e19ce89