Real-life efficacy and safety of nintedanib in systemic sclerosis-interstitial lung disease: data from an Italian multicentre study

Autor: Corrado Campochiaro, Giacomo De Luca, Maria-Grazia Lazzaroni, Giuseppe Armentaro, Amelia Spinella, Barbara Vigone, Barbara Ruaro, Anna Stanziola, Devis Benfaremo, Enrico De Lorenzis, Beatrice Moccaldi, Silvia Laura Bosello, Giovanna Cuomo, Lorenzo Beretta, Elisabetta Zanatta, Dilia Giuggioli, Nicoletta Del Papa, Paolo Airo, Marco Confalonieri, Gianluca Moroncini, Lorenzo Dagna, Marco Matucci-Cerinic

IntroductionNintedanib (NTD) has been shown to be effective in systemic sclerosis (SSc)-interstitial lung disease (ILD). Here we describe the efficacy and safety of NTD in a real-life setting.MethodsPatients with SSc-ILD treated with NTD were retrosp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b84ef2bf90800f561dffff49d0e031f6
https://hdl.handle.net/11577/3481905

Prognostic Role of Ventricular Ectopic Beats in Systemic Sclerosis: A Prospective Cohort Study Shows ECG Indexes Predicting the Worse Outcome

Autor: G. Canestrari, Giacomo De Luca, Francesca Augusta Gabrielli, F. Parisi, Filippo Crea, Gianfranco Ferraccioli, Leonarda Galiuto, G. Berardi, Silvia Laura Bosello, M. Rucco, Francesco Loperfido

Publikováno v: PLoS ONE, Vol 11, Iss 4, p e0153012 (2016)
PLoS ONE

Background: Arrhythmias are frequent in Systemic Sclerosis (SSc) and portend a bad prognosis, accounting alone for 6% of total deaths. Many of these patients die suddenly, thus prevention and intensified risk-stratification represent unmet medical ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f3a684f8e0a1d87785242e6685327e
http://hdl.handle.net/10807/79542

Long-term retention rate, adverse event temporal patterns and rescue treatment strategies of mycophenolate mofetil in systemic sclerosis: insights from real-life.

Autor: De Lorenzis E; Unit of Rheumatology, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; Scleroderma Program, Leeds Institute of Rheumatic and Musculoskeletal Diseases, University of Leeds, Leeds, United Kingdom., Natalello G; Unit of Rheumatology, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Pellegrino G; Rheumatology Unit, Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy., Verardi L; Unit of Rheumatology, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Batani V; Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milan, Italy., Lepri G; Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy., Stano S; Rheumatology Unit, Department of Emergency and Organs Transplantation, Università degli Studi di Bari Aldo Moro, Bari, Italy., Armentano G; Scleroderma Clinic, Dip. Reumatologia, ASST G. Pini-CTO, Università degli Studi di Milano., De Pinto M; Department of Rheumatology, University of Modena and Reggio Emilia, Modena, Italy., Motta F; Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy., Di Donato S; Scleroderma Program, Leeds Institute of Rheumatic and Musculoskeletal Diseases, University of Leeds, Leeds, United Kingdom., Kakkar V; Scleroderma Program, Leeds Institute of Rheumatic and Musculoskeletal Diseases, University of Leeds, Leeds, United Kingdom., Fiore S; Unit of Rheumatology, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Bisconti I; Rheumatology Unit, Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy., Campochiaro C; Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milan, Italy., Cometi L; Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy., Tonutti A; Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano, Italy., Spinella A; Department of Rheumatology, University of Modena and Reggio Emilia, Modena, Italy., Truglia S; Rheumatology Unit, Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy., Cavalli S; Scleroderma Clinic, Dip. Reumatologia, ASST G. Pini-CTO, Università degli Studi di Milano., De Santis M; Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy., Giuggioli D; Department of Rheumatology, University of Modena and Reggio Emilia, Modena, Italy., Del Papa N; Scleroderma Clinic, Dip. Reumatologia, ASST G. Pini-CTO, Università degli Studi di Milano., Guiducci S; Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy., Cacciapaglia F; Rheumatology Unit, Department of Emergency and Organs Transplantation, Università degli Studi di Bari Aldo Moro, Bari, Italy., De Luca G; Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milan, Italy., Iannone F; Rheumatology Unit, Department of Emergency and Organs Transplantation, Università degli Studi di Bari Aldo Moro, Bari, Italy., Ricceri V; Rheumatology Unit, Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy., Matucci Cerinic M; Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milan, Italy., D'Agostino MA; Unit of Rheumatology, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Del Galdo F; Scleroderma Program, Leeds Institute of Rheumatic and Musculoskeletal Diseases, University of Leeds, Leeds, United Kingdom., Bosello SL; Unit of Rheumatology, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

Publikováno v: Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2024 Sep 30. Date of Electronic Publication: 2024 Sep 30.

Concordance and Prognostic Relevance of Different Definitions of Systemic Sclerosis Interstitial Lung Disease Progression.

Autor: De Lorenzis E; Catholic University of the Sacred Heart, Division of Rheumatology - Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; University of Leeds, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, United Kingdom of Great Britain and Northern Ireland., Del Galdo F; University of Leeds, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, United Kingdom of Great Britain and Northern Ireland., Natalello G; Catholic University of the Sacred Heart, Division of Rheumatology - Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Lazio, Italy., Varone F; Catholic University of the Sacred Heart, Division of Pulmonology - Fondazione Policlinico Universitario A. Gemelli IRCCS, Rpme, Italy., Di Donato S; University of Leeds, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, United Kingdom of Great Britain and Northern Ireland., Verardi L; Catholic University of the Sacred Heart, Division of Rheumatology - Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Lazio, Italy., Calandriello L; Catholic University of the Sacred Heart, Department of Diagnostic Imaging, Oncological Radiotherapy and Haematology - Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Lazio, Italy., Kakkar V; University of Leeds, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, United Kingdom of Great Britain and Northern Ireland., Cerasuolo PG; Catholic University of the Sacred Heart, Division of Rheumatology - Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Lazio, Italy., Larici AR; Catholic University of the Sacred Heart, Department of Diagnostic Imaging, Oncological Radiotherapy and Haematology - Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., D'Agostino MA; Catholic University of the Sacred Heart, Division of Rheumatology - Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Bosello SL; Catholic University of the Sacred Heart, Division of Rheumatology - Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; silvialaura.bosello@policlinicogemelli.it., Richeldi L; Catholic University of the Sacred Heart, Division of Pulmonology - Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

Publikováno v: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2024 Jul 30. Date of Electronic Publication: 2024 Jul 30.

Practice pattern for the use of intravenous iloprost for the treatment of peripheral vasculopathy in systemic sclerosis: A case-control study from the Italian national multicenter "SPRING" (Systemic Sclerosis Progression InvestiGation) Registry.

Autor: Riccieri V; Department of Internal Medicine, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy., Pellegrino G; Department of Internal Medicine, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy.; Department of Rheumatology, IRCCS Ospedale Galeazzi-Sant'Ambrogio, Milan, Italy., Cipolletta E; Rheumatology Unit, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy., Giuggioli D; Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy., Bajocchi G; Rheumatology Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy., Bellando-Randone S; Department of Experimental and Clinical Medicine, Division of Rheumatology, AOUC, University of Florence, Florence, Italy., Dagna L; Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milano, Italy., Zanframundo G; Department of Rheumatology, Policlinico San Matteo, Pavia, Italy., Foti R; Rheumatology Unit, A.O.U Policlinico S. Marco, Catania, Italy., Cacciapaglia F; Rheumatology Unit, Department of Precision and Regenerative Medicine-Ionian Area, University of Bari 'Aldo Moro,' Bari, Italy., Cuomo G; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli,' Naples, Italy., Ariani A; Department of Medicine, Internal Medicine and Rheumatology, Azienda Ospedaliero Universitaria di Parma, Parma, Italy., Rosato E; Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy., Lepri G; Department of Experimental and Clinical Medicine, Division of Rheumatology, AOUC, University of Florence, Florence, Italy., Girelli F; Department of Medicine, Rheumatology Unit, Ospedale GB Morgagni-L Pierantoni, Forlì, Italy., Zanatta E; Rheumatology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy., Bosello SL; Institute of Rheumatology and Affine Sciences, Division of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy., Cavazzana I; Rheumatology and Clinical Immunology, Department of Clinical and Experimental Sciences, ASST Spedali Civili of Brescia and University of Brescia, Brescia, Italy., Ingegnoli F; Division of Clinical Rheumatology, ASST Pini, Department of Clinical Sciences & Community Health, Research Center for Adult and Pediatric Rheumatic Diseases, Research Center for Environmental Health, Università degli Studi di Milano, Milan, Italy., De Santis M; Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano, Italy., Murdaca G; Department of Internal Medicine, University of Genoa, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Abignano G; Rheumatology Institute of Lucania (IReL) and Rheumatology Department of Lucania, San Carlo Hospital, Potenza, Italy., Romeo N; Rheumatology Unit, ASO Santa Croce e Carle, Cuneo, Italy., Della Rossa A; Department of Rheumatology, University of Pisa, Pisa, Italy., Caminiti M; Departmental Rheumatology Unit, Grande Ospedale Metropolitano, Reggio Calabria, Italy., Iuliano A; Rheumatology Unit, San Camillo Forlanini Hospital, Rome, Italy., Ciano G; Hospital of Ariano Irpino, Local Health Department, Ariano Irpino, Italy., Beretta L; Referral Center for Systemic Autoimmune Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy., Bagnato G; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy., Lubrano E; Department of Rheumatology, University of Molise, Campobasso, Italy., De Andres I; Rheumatology Unit, Azienda Ospedaliera di Rilievo Nazionale ed Alta Specializzazione 'Garibaldi,' Catania, Italy., Giollo A; Rheumatology Section, Department of Medicine, University of Verona, Verona, Italy., Saracco M; Ospedale Mauriziano, Torino, Italy., Agnes C; San Lorenzo Hospital, Turin, Italy., Lumetti F; Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy., Spinella A; Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy., Magnani L; Rheumatology Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy., Campochiaro C; Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milano, Italy., De Luca G; Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milano, Italy., Codullo V; Department of Rheumatology, Policlinico San Matteo, Pavia, Italy., Visalli E; Rheumatology Unit, A.O.U Policlinico S. Marco, Catania, Italy., Di Vico C; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli,' Naples, Italy., Gigante A; Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy., Saccon F; Department of Medicine, Villa Salus Hospital, Venice, Italy., Grazia Lazzaroni M; Rheumatology and Clinical Immunology, Department of Clinical and Experimental Sciences, ASST Spedali Civili of Brescia and University of Brescia, Brescia, Italy., Franceschini F; Rheumatology and Clinical Immunology, Department of Clinical and Experimental Sciences, ASST Spedali Civili of Brescia and University of Brescia, Brescia, Italy., Generali E; Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano, Italy., Mennillo G; Rheumatology Institute of Lucania (IReL) and Rheumatology Department of Lucania, San Carlo Hospital, Potenza, Italy., Barsotti S; Department of Rheumatology, University of Pisa, Pisa, Italy., Pagano Mariano G; Departmental Rheumatology Unit, Grande Ospedale Metropolitano, Reggio Calabria, Italy., Calabrese F; Departmental Rheumatology Unit, Grande Ospedale Metropolitano, Reggio Calabria, Italy., Furini F; Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliera-Universitaria S. Anna di Ferrara, Ferrara, Italy., Vultaggio L; Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliera-Universitaria S. Anna di Ferrara, Ferrara, Italy., Parisi S; Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Turin, Italy., Peroni CL; Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Turin, Italy., Bianchi G; Rheumatology Unit, Department of Musculoskeletal Sciences, Local Health Trust 3, La Colletta Hospital, Genoa, Italy., Conti F; Department of Internal Medicine, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy., Cozzi F; Department of Medicine, Villa Salus Hospital, Venice, Italy., D'Angelo S; Rheumatology Institute of Lucania (IReL) and Rheumatology Department of Lucania, San Carlo Hospital, Potenza, Italy., Doria A; Rheumatology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy., Fusaro E; Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Turin, Italy., Govoni M; Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliera-Universitaria S. Anna di Ferrara, Ferrara, Italy., Guiducci S; Department of Experimental and Clinical Medicine, Division of Rheumatology, AOUC, University of Florence, Florence, Italy., Iannone F; Rheumatology Unit, Department of Precision and Regenerative Medicine-Ionian Area, University of Bari 'Aldo Moro,' Bari, Italy., Salvarani C; Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy., Sebastiani GD; Rheumatology Unit, San Camillo Forlanini Hospital, Rome, Italy., Ferri C; Rheumatology Unit, School of Medicine, University of Modena and Reggio Emilia, Modena, Italy., Matucci-Cerinic M; Department of Experimental and Clinical Medicine, Division of Rheumatology, AOUC, University of Florence, Florence, Italy., De Angelis R; Rheumatology Unit, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy.

Publikováno v: Journal of scleroderma and related disorders [J Scleroderma Relat Disord] 2024 Feb; Vol. 9 (1), pp. 38-49. Date of Electronic Publication: 2024 Jan 11.