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Akademický článek

HLA-C downregulation by HIV-1 adapts to host HLA genotype.

Publikováno v: PLoS Pathogens, Vol 14, Iss 9, p e1007257 (2018)

HIV-1 can downregulate HLA-C on infected cells, using the viral protein Vpu, and the magnitude of this downregulation varies widely between primary HIV-1 variants. The selection pressures that result in viral downregulation of HLA-C in some individua

Externí odkaz: https://doaj.org/article/fd77a141723449b993740096f7b2aca0

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Akademický článek

Sexually transmitted infection (STI) knowledge and perceptions among people in HIV-sero-different partnerships in rural southwestern Uganda.

Autor: Pooja Chitneni, Moran Owembabazi, Eunice Kanini, Simon Mwima, Mwebesa Bosco Bwana, Christina Psaros, Winnie R Muyindike, Jessica E Haberer, Lynn T Matthews

Publikováno v: PLOS Global Public Health, Vol 4, Iss 1, p e0002817 (2024)

Globally, over one million people acquire curable sexually transmitted infections (STI) each day. Understanding how people think about STIs is key to building culturally appropriate STI prevention and treatment programs. We explored STI knowledge and

Externí odkaz: https://doaj.org/article/bebde761e51840d3b43262523fa705d1

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Akademický článek

High PrEP uptake and objective longitudinal adherence among HIV-exposed women with personal or partner plans for pregnancy in rural Uganda: A cohort study.

Autor: Lynn T Matthews, Esther C Atukunda, Moran Owembabazi, Kato Paul Kalyebera, Christina Psaros, Pooja Chitneni, Craig W Hendrix, Mark A Marzinke, Peter L Anderson, Oluwaseyi O Isehunwa, Kathleen E Hurwitz, Kara Bennett, Winnie Muyindike, David R Bangsberg, Jessica E Haberer, Jeanne M Marrazzo, Mwebesa Bosco Bwana

Publikováno v: PLoS Medicine, Vol 20, Iss 2, p e1004088 (2023)

BackgroundIn Uganda, fertility rates and adult HIV prevalence are high, and many women conceive with partners living with HIV. Pre-exposure prophylaxis (PrEP) reduces HIV acquisition for women and, therefore, infants. We developed the Healthy Familie

Externí odkaz: https://doaj.org/article/46786adee7ed4d5780dd8be9948d9ad5

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STI prevalence, incidence, and partner notification among women in a periconception HIV prevention program in Uganda

Autor: Pooja Chitneni, Winnie Muyindike, Mwebesa Bosco Bwana, Moran Owembabazi, Kasey O’Neil, Paul Kato Kalyebara, Bethany Hedt-Gauthier, David R Bangsberg, Jeanne M Marrazzo, Angela Kaida, Jessica E Haberer, Lynn T Matthews

Publikováno v: International journal of STDAIDS. 33(9)

Background We provided sexually transmitted infection (STI) screening and facilitated partner notification and treatment among women participating in a periconception HIV prevention program in southwestern Uganda to understand follow-up STI incidence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecaef0e03f94cb52a002e774a05d84fc
https://pubmed.ncbi.nlm.nih.gov/35775125

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Akademický článek

Facility-Level Factors Influencing Retention of Patients in HIV Care in East Africa.

Autor: Beth Rachlis, Giorgos Bakoyannis, Philippa Easterbrook, Becky Genberg, Ronald Scott Braithwaite, Craig R Cohen, Elizabeth A Bukusi, Andrew Kambugu, Mwebesa Bosco Bwana, Geoffrey R Somi, Elvin H Geng, Beverly Musick, Constantin T Yiannoutsos, Kara Wools-Kaloustian, Paula Braitstein

Publikováno v: PLoS ONE, Vol 11, Iss 8, p e0159994 (2016)

Losses to follow-up (LTFU) remain an important programmatic challenge. While numerous patient-level factors have been associated with LTFU, less is known about facility-level factors. Data from the East African International epidemiologic Databases t

Externí odkaz: https://doaj.org/article/f296e54838c049648fff0f8440799eee

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A qualitative exploration to understand barriers and facilitators to daily oral PrEP uptake and sustained adherence among HIV-negative women planning for or with pregnancy in rural Southwestern Uganda

Autor: Esther Cathyln Atukunda, Moran Owembabazi, Madeline Claire Pratt, Christina Psaros, Winnie Muyindike, Pooja Chitneni, Mwebesa Bosco Bwana, David Bangsberg, Jessica Elizabeth Haberer, Jeanne Marrazzo, Lynn Turner Matthews

Publikováno v: Journal of the International AIDS Society. 25(3)

Antiretroviral pre-exposure prophylaxis (PrEP) may reduce periconception and pregnancy HIV incidence among women in settings, where gender power imbalances limit HIV testing, engagement in care and HIV viral suppression. We conducted qualitative inte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ce924b7238280f89604e14932b671d
https://pubmed.ncbi.nlm.nih.gov/35324081

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Sexually Transmitted Infection Prevalence Among Women at Risk for HIV Exposure Initiating Safer Conception Care in Rural, Southwestern Uganda

Autor: Mwebesa Bosco Bwana, David R. Bangsberg, Paul Kato Kalyebara, Nicholas Musinguzi, Angela Kaida, Lynn T. Matthews, Jeanne M. Marrazzo, Moran Owembabazi, Jessica E. Haberer, Kasey O’Neil, Winnie Muyindike, Pooja Chitneni

Publikováno v: Sex Transm Dis

Background Knowledge of sexually transmitted infection (STI) prevalence and risk factors is important to the development of tenofovir-based preexposure prophylaxis (PrEP) and safer conception programming. We introduced STI screening among women at ri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a743fd9fe8e8a2e7a1f733398a274e77
https://pubmed.ncbi.nlm.nih.gov/32404858

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Lower rates of ART initiation and decreased retention among ART-naïve patients who consume alcohol enrolling in HIV care and treatment programs in Kenya and Uganda

Autor: Constantin T. Yiannoutsos, Kara Wools-Kaloustian, Mwembesa Bosco Bwana, Jayne L Kulzer, Beverly S. Musick, Lameck Diero, Suzanne Goodrich, Ioannis Patsis, Patrick Oyaro, Steven A. Brown

Publikováno v: PLoS ONE
PLoS ONE, Vol 15, Iss 10, p e0240654 (2020)

ObjectivesAlmost 13 million people are estimated to be on antiretroviral therapy in Eastern and Southern Africa, and their disease course and program effectiveness could be significantly affected by the concurrent use of alcohol. Screening for alcoho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6381f5ac6c547775fb0461406d9f54f4
https://doi.org/10.1371/journal.pone.0240654

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D-dimer levels and traditional risk factors are associated with incident hypertension among HIV-infected individuals initiating antiretroviral therapy in Uganda

Autor: Russell P. Tracy, Winnie Muyindike, Jeffrey N. Martin, Mark J. Siedner, David R. Bangsberg, Tricia H. Burdo, Stephen Asiimwe, Bosco Bwana Mwebesa, A. Rain Mocello, Michael Kanyesigye, Samson Okello, Jessica E. Haberer, Peter W. Hunt, Yong Huang, Kenneth C. Williams, Yap Boum

Publikováno v: Journal of acquired immune deficiency syndromes (1999), vol 73, iss 4

OBJECTIVES We sought to describe blood pressure (BP) changes after antiretroviral therapy (ART) initiation and evaluate the association of markers of inflammation with incident hypertension in a cohort of HIV-infected individuals in Uganda. METHODS W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1f60133a27afb61580931b0c8c2e05
https://europepmc.org/articles/PMC5085880/

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