σ2-Receptor Ligand-Mediated Inhibition of Inwardly Rectifying K+ Channels in the Heart

Autor: Isabelle Baró, Pascal Bousquet, Jean Daniel Ehrhardt, Borys Manoury, Diane Zimmermann, Laurent Monassier, Weissenburger J, Patrice Jaillon, Chloé Bellocq, Hugues Greney

Publikováno v: Journal of Pharmacology and Experimental Therapeutics
Journal of Pharmacology and Experimental Therapeutics, American Society for Pharmacology and Experimental Therapeutics, 2007, 322 (1), pp.341-350
Journal of Pharmacology and Experimental Therapeutics, 2007, 322 (1), pp.341-350

The sigma(2)-receptor agonist, ifenprodil, was suggested as an inhibitor of G protein-coupled inwardly rectifying potassium channels. Nevertheless, an analysis of the role of sigma(2) receptors in cardiac electrophysiology has never been done. This w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb3eaee117c9ac77bf3181ad7d7bab5
https://doi.org/10.1124/jpet.107.122044