Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Borys Korchin"'
Autor:
Ravi A Madan, Christopher Heery, Claudia Palena, Caroline Jochems, Julius Strauss, Marijo Bilusic, Fatima Karzai, Jennifer L Marté, Charalampos Floudas, Peter J DeMaria, Katherine Lee-Wisdom, Angie Schwab, Jason Mark Redman, Eva Dombi, Brigitte Widemann, Borys Korchin, Tatiana Adams, Cesar Pico-Navarro
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/37a0f2d29a6c47d6940c4dc1bf5400ca
Autor:
Danielle M. Pastor, Katherine Lee-Wisdom, Andrew E. Arai, Arlene Sirajuddin, Douglas R. Rosing, Borys Korchin, James L. Gulley, Marijo Bilusic
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The emergence of the SARS-CoV-2 virus has been associated with perplexing clinical sequelae and phenomena that often have no clear link to the underlying infection. There is a wide spectrum of symptoms associated with infection, from minimal respirat
Externí odkaz:
https://doaj.org/article/f26417c6efc74bd5848f5bca45687ce8
Autor:
Arun Rajan, Jhanelle E. Gray, Siddhartha Devarakonda, Ruemu Birhiray, Borys Korchin, Erika Menius, Renee N. Donahue, Jeffrey Schlom, James L. Gulley
Publikováno v:
International Journal of Cancer. 152:447-457
CV301, a poxviral-based vaccine, has been evaluated in a phase 1 clinical trial (NCT02840994) and shown to be safe and immunologically active (phase 1a). Preclinical data support a combination of CV301 with programmed death-1 inhibitors, which has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a57899914a3e12d420952eefaa2ac20
https://doi.org/10.1002/ijc.34267
https://doi.org/10.1002/ijc.34267
Autor:
Jennifer L. Marte, Katherine Lee-Wisdom, Renee N. Donahue, Charalampos S. Floudas, Ravi A. Madan, Borys Korchin, Caroline Jochems, Jeffrey Schlom, Angie Schwab, Jason M. Redman, Fatima Karzai, Claudia Palena, Peter Joseph DeMaria, Eva Dombi, James L. Gulley, Brigitte C. Widemann, Marijo Bilusic, Tatiana Adams, Julius Strauss, Cesar Pico-Navarro, Christopher R. Heery
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundMVA-BN-brachyury-TRICOM is a recombinant vector-based therapeutic cancer vaccine designed to induce an immune response against brachyury. Brachyury, a transcription factor overexpressed in advanced cancers, has been associated with treatmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580476b5dfe51b6fdba8e9be5ecedacf
https://jitc.bmj.com/content/9/9/e003238.full
https://jitc.bmj.com/content/9/9/e003238.full
Autor:
Rashmi Chugh, Judy S. Wang, Anthony J. Olszanski, Breelyn A. Wilky, Paul Algate, Leah Plato, Alexander I. Spira, Borys Korchin, Jelle W. Kylstra
Publikováno v:
Journal of Clinical Oncology. 40:2611-2611
2611 Background: PSB205 is a new biological agent consisting of two engineered monoclonal antibodies (anti-PD-1 IgG4 and anti-CTLA-4 IgG1) expressed in a fixed ratio (2:1) from a single cell-line, manufactured as one product and dispensed from a sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::065fc3d4b8dab6d9e615367f3e50d3ab
https://doi.org/10.1200/jco.2022.40.16_suppl.2611
https://doi.org/10.1200/jco.2022.40.16_suppl.2611
Autor:
Katherine Lee-Wisdom, Borys Korchin, Douglas R. Rosing, Marijo Bilusic, James L. Gulley, Andrew E. Arai, Danielle M. Pastor, Arlene Sirajuddin
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology, Vol 10 (2020)
The emergence of the SARS-CoV-2 virus has been associated with perplexing clinical sequelae and phenomena that often have no clear link to the underlying infection. There is a wide spectrum of symptoms associated with infection, from minimal respirat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ed1c4ab78cda5fcec648399bed9106
http://europepmc.org/articles/PMC7717959
http://europepmc.org/articles/PMC7717959
Autor:
Marijo Bilusic, Ravi A. Madan, Fatima Karzai, Julius Strauss, Jennifer L. Marte, Katherine Lee-Wisdom, Renee N. Donahue, Jason M. Redman, Peter Joseph DeMaria, Charalampos S. Floudas, Borys Korchin, Houssein Abdul Sater, Tatiana Adams, Caroline Jochems, Jeffrey Schlom, Claudia Palena, James L. Gulley, Guenter Silbernagl, Cesar Pico-Navarro
Publikováno v:
Journal of Clinical Oncology. 39:2617-2617
2617 Background: Brachyury is a member of the T-box family of transcription factors which is overexpressed in several tumor types and has been associated with treatment resistance, epithelial to mesenchymal transition and metastatic potential. MVA-BN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e673f7c1af96c81b2d2bd7ced1e0e527
https://doi.org/10.1200/jco.2021.39.15_suppl.2617
https://doi.org/10.1200/jco.2021.39.15_suppl.2617
Autor:
Ye Chen, Yuexi Shi, Hongbo Lu, Richard B. Lock, Venkata Lokesh Battula, Deborah A. Thomas, Borys Korchin, Michael Andreeff, Hagop M. Kantarjian, Kensuke Kojima, Suzanne Spong, Marina Konopleva
Publikováno v:
Annals of Hematology. 93:485-492
Connective tissue growth factor (CTGF/CCN2) is involved in extracellular matrix production, tumor cell proliferation, adhesion, migration, and metastasis. Recent studies have shown that CTGF expression is elevated in precursor B-acute lymphoblastic l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e361ab2ed4e08267b76c57ba2873d688
https://doi.org/10.1007/s00277-013-1939-2
https://doi.org/10.1007/s00277-013-1939-2
Autor:
Michael Andreeff, Herbert A. Fritsche, Michael Fiegl, Borys Korchin, Zakar Mnjoyan, Ismael Samudio
Publikováno v:
Leukemia. 24:1364-1367
Physiological hypoxia promotes lipid raft and PI3K-dependent activation of MAPK 42/44 in leukemia cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce75a5c7e6479b0f7868fba853cd0ed6
https://doi.org/10.1038/leu.2010.94
https://doi.org/10.1038/leu.2010.94
Autor:
Borys Korchin, Ismael Samudio, Michael Andreeff, Hagop M. Kantarjian, Heinrich Taegtmeyer, Kumar Kaluarachchi, Michael Fiegl, Marina Konopleva, William G. Bornmann, Romain Harmancey, Seshagiri Duvvuri
Publikováno v:
Journal of Clinical Investigation. 120:142-156
The traditional view is that cancer cells predominately produce ATP by glycolysis, rather than by oxidation of energy-providing substrates. Mitochondrial uncoupling — the continuing reduction of oxygen without ATP synthesis — has recently been sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::705e4ef51b3fb739adc02fdbee51e17c
https://doi.org/10.1172/jci38942
https://doi.org/10.1172/jci38942