Synthesis and analgesic activity of new analogs of FELL tetrapeptide containing D-Phe in the first position

Autor: Boryana Borisova, Hristina Nocheva, Ivan Iliev, Marie Laronze-Cochard, Stéphane Gérard, Stoyko Petrin, Dancho Danalev

Publikováno v: Current Research in Biotechnology, Vol 8, Iss , Pp 100249- (2024)

Pain, whether acute or chronic, is one of the most unpleasant experiences. It can have different origins and long-term effects on the body starting from the trivial once such as physical discomfort, accompanying by emotional distress and going to the

Externí odkaz: https://doaj.org/article/6f9f10e6bea24619841347579daa1879

Synthesis, In Silico Logp Study, and In Vivo Analgesic Activity of Analogs of Tetrapeptide FELL

Autor: Boryana Borisova, Hristina Nocheva, Stéphane Gérard, Marie Laronze-Cochard, Stefan Dobrev, Silvia Angelova, Stoyko Petrin, Dancho Danalev

Publikováno v: Pharmaceuticals, Vol 16, Iss 8, p 1183 (2023)

Background: The inflammatory process represents a specific response of the organism’s immune system. More often, it is related to the rising pain in the affected area. Independently of its origin, pain represents a complex and multidimensional acut

Externí odkaz: https://doaj.org/article/6ec7a4ec312449d290621bd351b70cac

INTERDEPENDENCE BETWEEN PROFESSIONAL MOTIVATION AND SATISFACTION OF THE NURSING STAFF

Autor: Boryana Borisova, Biyanka Tornyova, Vanina Mihaylova, Tanya Paskaleva, Dimitar Shopov, Teodora Stoeva

Publikováno v: Journal of IMAB, Vol 25, Iss 3, Pp 2659-2662 (2019)

Motivation is a complex mental process that in its dynamics represents a specific cycle - a motivational cycle. It combines three basic elements: needs, motives and satisfaction. In the present article, data from a specific empirical study analyzes t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e03f1ceb03aa926183500b2ee1c1805f
https://doi.org/10.5272/jimab.2019253.2659

Disposable amperometric immunosensor for Saccharomyces cerevisiae based on carboxylated graphene oxide-modified electrodes

Autor: Concepción Parrado, José M. Pingarrón, Ana Briones-Pérez, María Arévalo-Villena, Abderrahmane Boujakhrout, Alfredo Sánchez, Reynaldo Villalonga, Paul E. D. Soto-Rodríguez, Boryana Borisova

Publikováno v: Analytical and Bioanalytical Chemistry. 410:7901-7907

A sensitive and disposable amperometric immunosensor for Saccharomyces cerevisiae was constructed by using carbon screen-printed electrodes modified with propionic acid-functionalized graphene oxide as transduction element. The affinity-based biosens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c764b0ed7f54c9ebf5d8d086aece55b
https://doi.org/10.1007/s00216-018-1410-2

5-Arylisothiazol-3(2H)-one-1,(1)-(di)oxides: A new class of selective tumor-associated carbonic anhydrases (hCA IX and XII) inhibitors

Autor: Antonella Fontana, Dimitar Dontchev, Michela De Grandis, Raimundo F. Miambo, Carine Machado, Benedetta Cornelio, Claudiu T. Supuran, Mariangela Ceruso, Marie Laronze-Cochard, Janos Sapi, Boryana Borisova, Rossana Riccioni

Publikováno v: European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2019, 175, pp.40-48. ⟨10.1016/j.ejmech.2019.04.072⟩

Sixteen 5-aryl-substituted isothiazol-3(2H)-one-1,(1)-(di)oxide analogs have been prepared from the corresponding 5-chloroisothiazol-3(2H)-one-1-oxide or −1,1-dioxide by a Suzuki-Miyaura cross-coupling reaction and screened for their inhibition pot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74bb47535b94d8aca5a4766ee7564b60
https://pubmed.ncbi.nlm.nih.gov/31071549