Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Borut Strukelj"'
Publikováno v:
Pharmacology & Pharmacy. 11:373-401
Immense changes have been introduced in psoriasis treatment, including successful systemic treatment of inflammation and education of psoriatic patients. The focus of this review is the latest developments in the understanding of the aetiopathogenesi
Publikováno v:
Molecules, Vol 16, Iss 1, Pp 790-817 (2011)
An increasing number of peptides with specific binding affinity to various protein and even non-protein targets are being discovered from phage display libraries. The power of this method lies in its ability to efficiently and rapidly identify ligand
Externí odkaz:
https://doaj.org/article/2077dfc3631143b5991ee97b60588287
Publikováno v:
Molecules, Vol 16, Iss 1, Pp 857-887 (2011)
Ligands selected from phage-displayed random peptide libraries tend to be directed to biologically relevant sites on the surface of the target protein. Consequently, peptides derived from library screenings often modulate the target protein’s activ
Externí odkaz:
https://doaj.org/article/0c59c39fef0541e882fbeb9a864c3ae9
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1028
Fullerenes are a relatively new group of compounds and represent a class of sphere-shaped molecules made exclusively of carbon atoms. Since their discovery in 1985, many aspects of both fullerene and its analogues have been intensively studied to rev
Publikováno v:
Immunology. 134(4)
A novel lectin, isolated from the basidiomycete mushroom Clitocybe nebularis and termed C. nebularis lectin (CNL), exhibits an immunostimulatory effect on the most potent antigen-presenting cells, the dendritic cells (DCs). Treatment of human monocyt
Publikováno v:
Phytotherapy research : PTR. 23(6)
Lipids are important components in human nutrition; however, their increased intake contributes to the development of obesity and can lead to multiple long-term complications. Pancreatic lipase (triacylglycerol acylhydrolase, EC 3.1.1.3) is a key enz
Autor:
Rade, Injac, Marija, Boskovic, Martina, Perse, Eva, Koprivec-Furlan, Anton, Cerar, Aleksandar, Djordjevic, Borut, Strukelj
Publikováno v:
Pharmacological reports : PR. 60(5)
Oxidative stress has an important role in the pathogenesis of doxorubicin (DOX)-induced nephrotoxicity. The aim of this study was to investigate the nephroprotective effects of fullerenol (FLR), an antioxidant agent, on DOX-induced nephrotoxicity. Th
Autor:
Daan, Crommelin, Theresa, Bermejo, Marco, Bissig, Jaak, Damiaans, Irene, Krämer, Patrick, Rambourg, Giovanna, Scroccaro, Borut, Strukelj, Roger, Tredree, Claudio, Ronco
Publikováno v:
Contributions to nephrology. 149
This contribution describes the present regulatory status in the EU of biosimilars, the generic versions of the first generation of therapeutic proteins. It points out why and where recombinant protein molecules and low-molecular-weight drugs differ
Autor:
Borut Strukelj, Patrick Rambourg, Roger Tredree, Giovanna Scroccaro, Theresa Bermejo, Claudio Ronco, Irene Krämer, Jaak Damiaans, Marco Bissig, Daan J.A. Crommelin
This contribution describes the present regulatory status in the EU of biosimilars, the generic versions of the first generation of therapeutic proteins. It points out why and where recombinant prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::563634315fa0497aedb917f2aa2d93b0
https://doi.org/10.1159/000085690
https://doi.org/10.1159/000085690
Publikováno v:
The Journal of Immunology. 192:137.1-137.1
TNFα is one of the most studied pro-inflammatory cytokines in the pathology of irritative bovel disease (IBD), including Crohn's disease and ulcerative colitis. The current therapy for the treatment of mid-to severe IBD is composed by corticosteroid