Gas-Phase Unfolding Reveals Stability Shifts Associated with Substrate Binding in Modular Polyketide Synthases.

Autor: Zhao C; Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States., Borotto NB; Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States., Schmidt J; Life Science Institute, Departments of Medicinal Chemistry, Chemistry, and Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan 48109, United States., Srivastava K; Life Science Institute, Departments of Medicinal Chemistry, Chemistry, and Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan 48109, United States., Lowell A; Life Science Institute, Departments of Medicinal Chemistry, Chemistry, and Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan 48109, United States., Hakansson K; Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States., Sherman DH; Life Science Institute, Departments of Medicinal Chemistry, Chemistry, and Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan 48109, United States., Ruotolo BT; Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States.

Publikováno v: Journal of the American Society for Mass Spectrometry [J Am Soc Mass Spectrom] 2024 Jul 25. Date of Electronic Publication: 2024 Jul 25.

Mobility-Assisted Pseudo-MS ³ Sequencing of Protein Ions.

Autor: Graham KA; Department of Chemistry, University of Nevada, 1664 N. Virginia Street, Reno, Nevada 89557, United States., Grisolia VJ; Department of Chemistry, University of Nevada, 1664 N. Virginia Street, Reno, Nevada 89557, United States., Borotto NB; Department of Chemistry, University of Nevada, 1664 N. Virginia Street, Reno, Nevada 89557, United States.

Publikováno v: Journal of the American Society for Mass Spectrometry [J Am Soc Mass Spectrom] 2024 Jun 26. Date of Electronic Publication: 2024 Jun 26.

Characterizing the top-down sequencing of protein ions prior to mobility separation in a timsTOF.

Autor: Graham KA; Department of Chemistry, University of Nevada, 1664 N. Virginia Street, Reno, NV 89557, USA. nborotto@unr.edu., Lawlor CF; Department of Chemistry, University of Nevada, 1664 N. Virginia Street, Reno, NV 89557, USA. nborotto@unr.edu., Borotto NB; Department of Chemistry, University of Nevada, 1664 N. Virginia Street, Reno, NV 89557, USA. nborotto@unr.edu.

Publikováno v: The Analyst [Analyst] 2023 Mar 27; Vol. 148 (7), pp. 1534-1542. Date of Electronic Publication: 2023 Mar 27.

Collision-Induced Unfolding of Native-like Protein Ions Within a Trapped Ion Mobility Spectrometry Device.

Autor: Borotto NB; Department of Chemistry, University of Nevada, 1664 N. Virginia Street, Reno, Nevada 89557, United States., Osho KE; Department of Chemistry, University of Nevada, 1664 N. Virginia Street, Reno, Nevada 89557, United States., Richards TK; Department of Chemistry, University of Nevada, 1664 N. Virginia Street, Reno, Nevada 89557, United States., Graham KA; Department of Chemistry, University of Nevada, 1664 N. Virginia Street, Reno, Nevada 89557, United States.

Publikováno v: Journal of the American Society for Mass Spectrometry [J Am Soc Mass Spectrom] 2022 Jan 05; Vol. 33 (1), pp. 83-89. Date of Electronic Publication: 2021 Dec 06.

Measuring the Energy Barrier of the Structural Change That Initiates Amyloid Formation.

Autor: Arden BG; Department of Chemistry, University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States., Borotto NB; Department of Chemistry, University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States., Burant B; Department of Chemistry, University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States., Warren W; Department of Chemistry, University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States., Akiki C; Department of Chemistry, University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States., Vachet RW; Department of Chemistry, University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States.

Publikováno v: Analytical chemistry [Anal Chem] 2020 Apr 07; Vol. 92 (7), pp. 4731-4735. Date of Electronic Publication: 2020 Mar 17.