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Autor:
de Heuvel, Erik, Singh, Abhimanyu K., Boronat, Pierre, Kooistra, Albert J., van der Meer, Tiffany, Sadek, Payman, Blaazer, Antoni R., Shaner, Nathan C., Bindels, Daphne S., Caljon, Guy, Maes, Louis, Sterk, Geert Jan, Siderius, Marco, Oberholzer, Michael, de Esch, Iwan J.P., Brown, David G., Leurs, Rob
Publikováno v:
In Bioorganic & Medicinal Chemistry 15 September 2019 27(18):4013-4029
Autor:
FitzGerald, Edward A., Butko, Margaret T., Boronat, Pierre, Cederfelt, Daniela, Abramsson, Mia, Ludviksdottir, Hildur, van Muijlwijk-Koezen, Jacqueline E., de Esch, Iwan J.P., Dobritzsch, Doreen, Young, Tracy, Danielson, U. Helena
Publikováno v:
RSC Advances, 11(13), 7527-7537. Royal Society of Chemistry
FitzGerald, E A, Butko, M T, Boronat, P, Cederfelt, D, Abramsson, M, Ludviksdottir, H, van Muijlwijk-Koezen, J E, de Esch, I J P, Dobritzsch, D, Young, T & Danielson, U H 2021, ' Discovery of fragments inducing conformational effects in dynamic proteins using a second-harmonic generation biosensor ', RSC Advances, vol. 11, no. 13, pp. 7527-7537 . https://doi.org/10.1039/d0ra09844b
FitzGerald, E A, Butko, M T, Boronat, P, Cederfelt, D, Abramsson, M, Ludviksdottir, H, van Muijlwijk-Koezen, J E, de Esch, I J P, Dobritzsch, D, Young, T & Danielson, U H 2021, ' Discovery of fragments inducing conformational effects in dynamic proteins using a second-harmonic generation biosensor ', RSC Advances, vol. 11, no. 13, pp. 7527-7537 . https://doi.org/10.1039/d0ra09844b
Biophysical screening of compound libraries for the identification of ligands that interact with a protein is efficient, but does typically not reveal if (or how) ligands may interfere with its functional properties. For this a biochemical/functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ffa8fc4121ba2b921512ad45fff58b3d
https://hdl.handle.net/1871.1/4e905709-eefd-4ab9-974c-f4e66095eaca
https://hdl.handle.net/1871.1/4e905709-eefd-4ab9-974c-f4e66095eaca