Zobrazeno 1 - 10
of 684
pro vyhledávání: '"Boron neutron capture therapy (BNCT)"'
Publikováno v:
Cancer Communications, Vol 44, Iss 8, Pp 893-909 (2024)
Abstract Boron neutron capture therapy (BNCT) is a cancer treatment modality based on the nuclear capture and fission reactions that occur when boron‐10, a stable isotope, is irradiated with neutrons of the appropriate energy to produce boron‐11
Externí odkaz:
https://doaj.org/article/1110ba6dabf644cb9d8602bc5ff56dd4
Publikováno v:
Frontiers in Nuclear Engineering, Vol 3 (2024)
IntroductionBoron Neutron Capture Therapy (BNCT) is a promising cancer therapy. At present, development of accelerator based neutron source (ABNS) is underway to be utilized as a neutron source instead of nuclear reactor. However, it is known that th
Externí odkaz:
https://doaj.org/article/24cabc8a6ad84844bdd93f1ef13abf8c
Autor:
Satoshi Nakamura, Mihiro Takemori, Tetsu Nakaichi, Yasunori Shuto, Tairo Kashihara, Kotaro Iijima, Takahito Chiba, Hiroki Nakayama, Yuka Urago, Shuka Nishina, Yuta Kobayashi, Hironori Kishida, Shoji Imamichi, Kana Takahashi, Mitsuko Masutani, Hiroyuki Okamoto, Teiji Nishio, Jun Itami, Hiroshi Igaki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Accelerator-based boron neutron capture therapy (BNCT) systems employing a solid-state lithium target indicated the reduction of neutron flux over the lifetime of a target, and its reduction could represent the neutron flux model. This study
Externí odkaz:
https://doaj.org/article/a11c89c95e2e4a4884733c87071bb098
Autor:
Ryo Kayama, Kohei Tsujino, Shinji Kawabata, Yoshiki Fujikawa, Hideki Kashiwagi, Yusuke Fukuo, Ryo Hiramatsu, Takashi Takata, Hiroki Tanaka, Minoru Suzuki, Naonori Hu, Shin-Ichi Miyatake, Toshihiro Takami, Masahiko Wanibuchi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Boron neutron capture therapy (BNCT) is a type of targeted particle radiation therapy with potential applications at the cellular level. Spinal cord gliomas (SCGs) present a substantial challenge owing to their poor prognosis and the lack of
Externí odkaz:
https://doaj.org/article/758ab44f8fd74a7f9e03d0cf8e72655d
Publikováno v:
EPJ Techniques and Instrumentation, Vol 10, Iss 1, Pp 1-15 (2023)
Abstract Recently, progress in technology for accelerator-based neutron sources has increased attention regarding boron neutron capture therapy (BNCT). BNCT is a type of radiotherapy that combines neutrons and boron drugs and is expected to be used i
Externí odkaz:
https://doaj.org/article/ccaba439a2774c52841b788cba8e5f25
Autor:
Sachie Kusaka, Nikolaos Voulgaris, Kazuki Onishi, Junpei Ueda, Shigeyoshi Saito, Shingo Tamaki, Isao Murata, Takushi Takata, Minoru Suzuki
Publikováno v:
Cells, Vol 13, Iss 19, p 1610 (2024)
In recent years, various drug delivery systems circumventing the blood–brain barrier have emerged for treating brain tumors. This study aimed to improve the efficacy of brain tumor treatment in boron neutron capture therapy (BNCT) using cerebrospin
Externí odkaz:
https://doaj.org/article/94c776b44a054f7b8c0434d9e0f34ada
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 9, Pp 6986-6994 (2023)
The output constancy of the accelerator used for boron neutron capture therapy (BNCT) is essential to ensuring anti-tumor efficacy and safety. BNCT as currently practiced requires a wide variety of beam quality assessments to ensure that RBE dose err
Externí odkaz:
https://doaj.org/article/fbbf398b3be04a52ac3a7a07bb653ee2
Autor:
Hiroshi Igaki, Satoshi Nakamura, Naoya Yamazaki, Tomoya Kaneda, Mihiro Takemori, Tairo Kashihara, Naoya Murakami, Kenjiro Namikawa, Tetsu Nakaichi, Hiroyuki Okamoto, Kotaro Iijima, Takahito Chiba, Hiroki Nakayama, Ayaka Nagao, Madoka Sakuramachi, Kana Takahashi, Koji Inaba, Kae Okuma, Yuko Nakayama, Kazuaki Shimada, Hitoshi Nakagama, Jun Itami
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
This study reports the first patient treatment for cutaneous malignant melanoma using a linear accelerator-based boron neutron capture therapy (BNCT) system. A single-center open-label phase I clinical trial had been conducted using the system since
Externí odkaz:
https://doaj.org/article/c1a4c84fee7c4fe6bf99af8f0c0f21a7
Publikováno v:
Current Oncology, Vol 29, Iss 10, Pp 7868-7886 (2022)
Boron neutron capture therapy (BNCT) is a binary modality that is used to treat a variety of malignancies, using neutrons to irradiate boron-10 (10B) nuclei that have entered tumor cells to produce highly linear energy transfer (LET) alpha particles
Externí odkaz:
https://doaj.org/article/e59f30b2327d4668a536a1c67f751f4e
Autor:
Yoshiki Fujikawa, Shinji Kawabata, Kohei Tsujino, Hideki Kashiwagi, Yusuke Fukuo, Ryo Hiramatsu, Hiroki Tanaka, Naonori Hu, Toshihiro Takami, Masahiko Wanibuchi
Publikováno v:
Proceedings, Vol 100, Iss 1, p 13 (2024)
Boron Neutron Capture Therapy (BNCT) is a particle beam therapy that enables the precise targeting of tumors at the cellular level [...]
Externí odkaz:
https://doaj.org/article/37e8d1751b104f71b219e5812302f395