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1040-G Novel phytochemicals-based media (added as a supplement) improves the exhaustion and activation phenotype of NK cells cultured in commercially available NK cell media

Autor: Rachit Ohri, Marc A Gillig, Nicholas Ingala, Karissa Mennes, Borom Chean, Mirok German, Jeffrey Bowler

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)

Externí odkaz: https://doaj.org/article/1a7406d48fd54659bad68e7ae15ec07c

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333 Novel phytochemicals-based cell culture medium mitigates natural killer (NK) cellular exhaustion and enhances mature subpopulations, leading to higher anticancer cytotoxic activity

Autor: Marc Gillig, Rafet Amoor, Nicholas Ingala, Borom Chean, Rachit Ohri

Publikováno v: Regular and Young Investigator Award Abstracts.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d7c97b1eed4aad481b933981a9963792
https://doi.org/10.1136/jitc-2022-sitc2022.0333

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210 A novel medium for increased cytotoxicity and serum-minimal ex vivo expansion of natural killer (NK) cellular immunotherapies

Autor: Marc Gillig, Graeme Lambert, Matthew Forsberg, Donna Sonntag, Jason Cahoon, Rafet Amoor, Borom Chean, Lea Picard, Sabine Wingert, Caroline Hull, Jacki Kornbluth, Carsten Watzl, Christian Capitini, Rachit Ohri

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)

BackgroundDespite significant clinical breakthroughs,1 2 cellular immunotherapy remains unacceptably variable in performance3 and impractically expensive for mainstream adoption.4 These hurdles are particularly true for new cancer immunotherapies wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a9267dedd8b415615f0862bddda9bd3
https://doi.org/10.1136/jitc-2021-sitc2021.210

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