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Exploring the uncharted seas: Metabolite profiling unleashes the anticancer properties of Oscillatoria salina

Autor: Bornita Das, Asharani Prusty, Subhajeet Dutta, Aditi Maulik, Yogita Dahat, Deepak Kumar, Sucheta Tripathy

Publikováno v: Heliyon, Vol 10, Iss 16, Pp e36048- (2024)

Marine cyanobacteria offer a rich source of varied natural products with both chemical and biological diversity. Oscillatoria salina (O. salina) is a filamentous non-heterocystous marine cyanobacterium from Oscillatoriaceae family. In this investigat

Externí odkaz: https://doaj.org/article/eb2d508c2b904faea69811230159ae05

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Dietary phytochemicals in the regulation of epithelial to mesenchymal transition and associated enzymes: A promising anticancer therapeutic approach

Autor: Anupam Bishayee, Bornita Das, Nivedita Sarkar, Dona Sinha

Publikováno v: Seminars in Cancer Biology. 56:196-218

Epithelial to mesenchymal transition (EMT) is a biological phenomenon that plays a primordial role for initiation of metastasis. It renders cancer cells with increased self-renewal and tumor-initiating capabilities and exacerbated resistance to apopt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da526f1cd1fafa4b472ae8c37bee6221
https://doi.org/10.1016/j.semcancer.2018.11.007

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Diallyl disulphide suppresses the cannonical Wnt signaling pathway and reverses the fibronectin-induced epithelial mesenchymal transition of A549 lung cancer cells

Autor: Dona Sinha, Bornita Das

Publikováno v: Food & Function. 10:191-202

Globally, non-small cell lung cancer is a leading cause of cancer-related mortality and about 40% of these cancers are detected in the metastatic stage. Epithelial mesenchymal transition (EMT) plays a critical role during malignant transformation, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfac83820f674309d0f74249da5ef0ad
https://doi.org/10.1039/c8fo00246k

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Arsenal of Phytochemicals to Combat Against Arsenic-Induced Mitochondrial Stress and Cancer

Autor: Anupam Bishayee, Bornita Das, Nivedita Sarkar, Dona Sinha

Publikováno v: Antioxidantsredox signaling. 33(17)

Significance: Phytochemicals are important dietary constituents with antioxidant properties. They affect various signaling pathways involved in the overall maintenance of interior milieu of the cell. Arsenic, an environmental toxicant, is well known

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108d0b0e3205dfca0fbd2fc4bf612dc5
https://pubmed.ncbi.nlm.nih.gov/31813247

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6-Gingerol inhibits Vibrio cholerae-induced proinflammatory cytokines in intestinal epithelial cells via modulation of NF-κB

Autor: Atul Katarkar, Keya Chaudhuri, Pallashri Saha, Aritra Bhattacharyya, Bornita Das

Publikováno v: Pharmaceutical Biology. 54:1606-1615

Context The effect of 6-gingerol (6G), the bioactive component of Zingiber officinale Roscoe (Zingiberaceae), in the reduction of Vibrio cholerae (Vibrionaceae)-induced inflammation has not yet been reported. Materials and methods Cell viability assa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b4b06706dc974a84c51f8de840825f
https://doi.org/10.3109/13880209.2015.1110598

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Role of 6-Gingerol in Reduction of Cholera Toxin Activity In Vitro and In Vivo

Autor: Pallashri Saha, Keya Chaudhuri, Bornita Das

Publikováno v: Antimicrobial Agents and Chemotherapy. 57:4373-4380

Vibrio cholerae is one of the major bacterial pathogens responsible for the devastating diarrheal disease called cholera. Chemotherapy is often used against V. cholerae infections; however, the emergence of V. cholerae with multidrug resistance (MDR)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b94a928abc99a46540e07e0ba0edc6
https://doi.org/10.1128/aac.00122-13

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Amelioration of sodium arsenite induced toxicity by diallyl disulfide, a bioactive component of garlic: the involvement of antioxidants and the chelate effect

Autor: Keya Chaudhuri, Bornita Das

Publikováno v: RSC Advances. 4:20964

Chronic exposure to high concentrations of arsenic in drinking water poses severe health problems. Despite arsenic being a severe health hazard, a safe and effective remedy against arsenic poisoning remains elusive. Previously, studies from our group

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4adf823842f4c786b01110972a4509a1
https://doi.org/10.1039/c4ra00338a

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