Zobrazeno 1 - 10
of 3 206
pro vyhledávání: '"Borneol"'
Autor:
Yuhsien Lai, Xuesong Wu, Zhuoyu Jiang, Yifei Fang, Xiuting Liu, Dan Hong, Yanyun Jiang, Guozhen Tan, Shiqi Tang, Siyao Lu, David Wei, Sam T. Hwang, Kit S. Lam, Liangchun Wang, Yanyu Huang, Zhenrui Shi
Publikováno v:
Bioactive Materials, Vol 41, Iss , Pp 83-95 (2024)
Psoriasis, an immune-mediated inflammatory skin disorder characterized by a chronically relapsing-remitting course, continues to be primarily managed through topical therapy. While oral administration of tyrosine kinase 2 inhibitors (TYK2i) stands as
Externí odkaz:
https://doaj.org/article/d2630ead11fe4a0e992129147a05d852
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
ObjectiveTo investigate the effect of (+)-borneol on neuroinflammation and microglia phenotype polarization in epileptogenesis and its possible mechanism.MethodsBased on mouse models of status epilepticus (SE) induced by pilocarpine, and treated with
Externí odkaz:
https://doaj.org/article/a487d98c34fc4153863dfce4e639dff2
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionTraditional Chinese medicine Gastrodia elata Blume (GEB) possesses properties that soothe the liver and dispel wind. Its constituents exhibit numerous pharmacological properties, including neuroprotective effects, analgesic properties for
Externí odkaz:
https://doaj.org/article/a2a1fc6a04f04715bb919e8c2fd81955
Autor:
Kiseok KWON
Publikováno v:
Uisahak, Vol 33, Iss 1, Pp 1-57 (2024)
Borneol(龍腦, yongnoe) was a fragrance and medicinal ingredient with unique efficacy. However, it could be produced only in tropical Southeast Asia and obtained only through international trade. In addition, camphor(樟腦, jangnoe) with similar ma
Externí odkaz:
https://doaj.org/article/cb36c7d3f6644e4aa649ca85e1a48466
Akademický článek
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Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Ischemia/reperfusion (IR) can induce deleterious responses such as apoptosis, inflammation, and oxidative stress; however, there are currently no efficient therapeutics to treat IR brain injury. Dragon’s blood (DB) plays a significant role in treat
Externí odkaz:
https://doaj.org/article/343da4709b54433088c027177f66da73
Autor:
Sehrish Imran, Yamin Bibi, Li-E Yang, Abdul Qayyum, Wei He, Jiazhen Yang, Xiaomeng Yang, Xiaoying Pu, Xia Li, Yawen Zeng
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e27492- (2024)
Background: The Zingiberaceae family serves as a diverse repository of bioactive phytochemicals, comprising approximately 52 genera and 1300 species of aromatic perennial herbs distinguished by their distinct creeping horizontal or tuberous rhizomes.
Externí odkaz:
https://doaj.org/article/aaad264e85e443478becd3f62418216a
Autor:
Maurício Pires de Moura do Amaral, Melquisedeque da Rocha Viana, Altamiro Teixeira Osório, Luciano da Silva Lopes, Fabrício Pires de Moura do Amaral, Massimo Lucarini, Alessandra Durazzo, Daniel Dias Rufino Arcanjo, Rita de Cássia Meneses Oliveira
Publikováno v:
Drugs and Drug Candidates, Vol 2, Iss 2, Pp 486-497 (2023)
Opioids such as morphine are the first choice in acute and chronic pain treatment. However, they lead to addiction. Several studies have searched (i) to find a molecule that can replace morphine use or (ii) to reduce its adverse effects. This work ai
Externí odkaz:
https://doaj.org/article/db34f1bb997a41cf941b53eef47ae76e
Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation
Autor:
Huan Li, Chao Song, Yang Zhang, Guohao Liu, Hailong Mi, Yachao Li, Zhiye Chen, Xiaoyu Ma, Po Zhang, Lidong Cheng, Peng Peng, Hongtao Zhu, Zirong Chen, Minhai Dong, Sui Chen, Hao Meng, QunGen Xiao, Honglian Li, Qiulian Wu, Baofeng Wang, Suojun Zhang, Kai Shu, Feng Wan, Dongsheng Guo, Wenchao Zhou, Lin Zhou, Feng Mao, Jeremy N. Rich, Xingjiang Yu
Publikováno v:
Advanced Science, Vol 11, Iss 7, Pp n/a-n/a (2024)
Abstract Glioblastoma (GBM) is a lethal cancer characterized by hypervascularity and necrosis associated with hypoxia. Here, it is found that hypoxia preferentially induces the actin‐binding protein, Transgelin (TAGLN), in GBM stem cells (GSCs). Me
Externí odkaz:
https://doaj.org/article/95216e81a5c74d7e8e6af9ccdf165215
Publikováno v:
PeerJ, Vol 12, p e16691 (2024)
Background Gliomas are characterized by high mortality rates and resistance. Even with conventional chemotherapy the prognosis of glioblastoma remains poor. Many medications are not optimally effective due to limited bioavailability. The bioavailabil
Externí odkaz:
https://doaj.org/article/2503c1e25b534631ae9114cb3d387a92