Zobrazeno 1 - 10 of 998 pro vyhledávání: '"Bormans, G"'
1
Akademický článek
Positron-Emission Tomography Imaging of Long-Term Shape Recognition Challenges
Autor: Rosier, A., Cornette, L., Dupont, P., Bormans, G., Michiels, J., Mortelmans, L., Orban, G. A.
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 1997 Jul 01. 94(14), 7627-7632.
Externí odkaz: https://www.jstor.org/stable/42730
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2
Akademický článek
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3
In vitro assessment of [¹⁸F]JHU94620-d8 to determine the expression of cannabinoid receptor 2 – a prognostic biomarker in breast cancer
Autor: Heerklotz, A., Moldovan, R.-P., Bormans, G., Pietzsch, J., Belter, B., Kopka, K., Gündel, D.
Publikováno v: EMIM 2023-European Molecular Imaging Meeting, 14.-17.03.2023, Salzburg, Österreich
The cannabinoid receptor 2 (CB2R) is involved in inflammatory processes [1], whereby an increased expression correlates with malignancy in various cancer types like human epidermal growth receptor 2 positive (HER2+) or triple negative breast cancer (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::1a6143ab816688b9e1c0a42aefba4b1b
https://www.hzdr.de/publications/Publ-35439-2
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4
Data publication: Enantioselective Synthesis, Structure Activity Relationship, Radiofluorination and Biological Evaluation of [18F]RM365, a Novel Radioligand for Imaging the Human Cannabinoid Receptor Type 2 (CB2R) in the Brain with PET
Autor: Teodoro, R., Gündel, D., Deuther-Conrad, W., Toussaint, M., Wenzel, B., Bormans, G., Kopka, K., Brust, P., Moldovan, R.-P.
Publikováno v: Publication date: 2023-04-05 Open accessDOI: 10.14278/rodare.2251Versions: 10.14278/rodare.2252License: CC-BY-4.0
The development of cannabinoid receptor type 2 (CB2R) PET radioligands has been intensively explored due to the pronounced CB2R upregulation in various pathological conditions, such as neuroinflammation and cancer. Herein we report on the enantiosele
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::81c719fa7ae9f22edd3ded1c08e5a968
https://www.hzdr.de/publications/Publ-36778-1
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5
Akademický článek
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6
Structure-Based Design, Optimization and Development of [18F]LU13, a novel radioligand for CB2R Imaging in the Brain with PET
Autor: Gündel, D., Deuther-Conrad, W., Ueberham, L., Kaur, S., Otikova, E., Teodoro, R., Lai, T. H., Clauß, O., Scheunemann, M., Bormans, G., Bachmann, M., Kopka, K., Brust, P., Moldovan, R.-P.
Publikováno v: Journal of Medicinal Chemistry 65(2022)13, 9034-9049
The cannabinoid receptor type 2 (CB2R) is an attractive target for diagnosis and therapy of neurodegenerative diseases and cancer. Recently, we reported a novel naphthyrid-2-one based positron-emission tomography (PET) radioligand for imaging of the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::8c3875da3c61ce5c8eef8ff8cfb092f1
https://www.hzdr.de/publications/Publ-33987-1
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7
Investigation of the Cannabinoid Receptor 2 (CB2R) Expression and Preliminary In Vitro Evaluation of the CB2R Specific PET Radioligand [18F]JHU94620-d8 in Different Breast Cancer Models
Autor: Heerklotz, A., Moldovan, R.-P., Deuther-Conrad, W., Bormans, G., Pietzsch, J., Belter, B., Kopka, K., Gündel, D.
Publikováno v: MOBI 2022, 15.-16.09.2022, Leipzig, Deutschland
5th GyMICMolecular Imaging Symposium, 15.-16.09.2022, Leipzig, Deutschland
Introduction The cannabinoid receptor 2 (CB2R) is involved in inflammatory processes [1], whereby an increased expression correlates with malignancy in various cancer types like human epidermal growth receptor 2 positive (HER2+) or triple negative br
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::42096d48ed76b097374756dffd4c1224
https://www.hzdr.de/publications/Publ-34950-2
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8
Data Publication: Structure-Based Design, Optimization and Development of [18F]LU13, a novel radioligand for CB2R Imaging in the Brain with PET
Autor: Moldovan, R.-P., Gündel, D., Deuther-Conrad, W., Ueberham, L., Kaur, S., Otikova, E., Teodoro, R., Lai, T. H., Clauß, O., Scheunemann, M., Bormans, G., Kopka, K., Bachmann, M., Brust, P.
Publikováno v: Publication date: 2022-08-09 Open accessDOI: 10.14278/rodare.1380Versions: 10.14278/rodare.1381License: CC-BY-4.0
The cannabinoid receptor type 2 (CB2R) is an attractive target for diagnosis and therapy of neurodegenerative diseases and cancer. Recently, we reported a novel naphthyrid-2-one based positron-emission tomography (PET) radioligand for imaging of the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::40e87f08e83747de9b9183b6c9962ddf
https://www.hzdr.de/publications/Publ-34030-1
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9
Evaluation of [18F]LU14 and [18F]LU13 in a rat model with a local overexpression of the human cannabinoid receptor 2 in the brain with PET
Autor: Gündel, D., Deuther-Conrad, W., Ueberham, L., Teodoro, R., Bormans, G., Toussaint, M., Kopka, K., Bachmann, M., Brust, P., Moldovan, R.-P.
Publikováno v: Turku PET Symposium 2022, 03.-06.06.2022, Turku, Finland
Objectives: An upregulation of cannabinoid receptors type 2 (CB2) has been reported in association with inflammation processes, traumatic brain injury, neurodegeneration and cancer.[1] The activation of CB2 leads to an anti-inflammatory action. There
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::b2064c3b34ea8a1785c7ac29964a9eb8
https://www.hzdr.de/publications/Publ-34261-2
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