Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Borko Javonovic"'
Autor:
Chung Lee, William J. Catalona, Yinglu Guo, Paul Lindholm, Michael Pins, Borko Javonovic, Adekunle A. Raji, Guangyu Yang, Shilajit D. Kundu, Norm Smith, James Kozlowski, Ximing J. Yang, Lin Chen, Lihua J. Zhu, Thomas L. Jang, Brian T. Helfand, Qiang Zhang
Supplementary Data from Nuclear Factor-κB-Mediated Transforming Growth Factor-β-Induced Expression of Vimentin Is an Independent Predictor of Biochemical Recurrence after Radical Prostatectomy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14844ba6dbabee583bf9a7602a8b476d
https://doi.org/10.1158/1078-0432.22439415.v1
https://doi.org/10.1158/1078-0432.22439415.v1
Autor:
Qiang Zhang, Lin Chen, Brian T Helfand, Thomas L Jang, Vidit Sharma, James Kozlowski, Timothy Michael Kuzel, Lihua J Zhu, Ximing J Yang, Borko Javonovic, Yinglu Guo, Scott Lonning, Jay Harper, Beverly A Teicher, Charles Brendler, Nengwang Yu, William J Catalona, Chung Lee
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25168 (2011)
DNA methyltransferase (DNMT) is one of the major factors mediating the methylation of cancer related genes such as TGF-β receptors (TβRs). This in turn may result in a loss of sensitivity to physiologic levels of TGF-β in aggressive prostate cance
Externí odkaz:
https://doaj.org/article/14a8162f94b04b4cb87f816db631a2f1
Autor:
James M. Kozlowski, Guang Yu Yang, Paul F. Lindholm, Adekunle Raji, Chung Lee, Shilajit Kundu, Thomas L. Jang, Lihua Julie Zhu, Norm D. Smith, William J. Catalona, Yinglu Guo, Ximing J. Yang, Brian T. Helfand, Michael R. Pins, Borko Javonovic, Qiang Zhang, Lin Chen
Publikováno v:
Clinical Cancer Research. 15:3557-3567
Purpose: Transforming growth factor-β (TGF-β)-mediated epithelial-to-mesenchymal transition (EMT) has been shown to occur in some cancers; however, the pathway remains controversial and varies with different cancers. In addition, the mechanisms by
Autor:
Seong-Jin Kim, Richard Meagher, Timothy M. Kuzel, Qiang Zhang, Yinglu Guo, Shilajit Kundu, Norman M. Greenberg, Ximing J. Yang, Chung Lee, Michael R. Pins, Robert E. Meyer, Borko Javonovic
Publikováno v:
Molecular Cancer Therapeutics. 5:1733-1743
Transforming growth factor-β (TGF-β) is a potent immunosuppressant. Overproduction of TGF-β by tumor cells leads to evasion of host immune surveillance and tumor progression. Results of our early studies showed that adoptive transfer of tumor-reac
Autor:
Luk Van Parijs, Borko Javonovic, Larry Wong, Norm D. Smith, Seong-Jin Kim, Robert E. Meyer, Shilajit Kundu, Irwin Park, Yinglu Guo, Qiang Zhang, Thomas L. Jang, Norman M. Greenberg, Ximing J. Yang, Timothy M. Kuzel, Michael R. Pins, Chung Lee
Publikováno v:
The Prostate. 66:235-247
Background TGF-beta is a potent immunosuppressant. High levels of TGF-beta produced by cancer cells have a negative inhibition effect on surrounding host immune cells and leads to evasion of the host immune surveillance and tumor progression. In the
Autor:
Chung Lee, Brian T. Helfand, Julie Zhu, Qiang Zhang, Borko Javonovic, Lin Chen, Norm D. Smith, Yinglu Guo
Publikováno v:
Journal of Urology. 183
Publikováno v:
Journal of Urology. 183
Autor:
Michael R. Pins, Chung Lee, Ximing J. Yang, Seong-Jin Kim, Borko Javonovic, Jonathan N. Rubenstein, Irwin Park, Thomas L. Jang, Qiang Zhang
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 19(9)
Prostate cancers often develop insensitivity to TGF-beta to gain a growth advantage. In this study, we explored the status of promoter methylation of TGF-beta receptors (TbetaRs) in a prostate cancer cell line, LNCaP, which is insensitive to TGF-beta
Autor:
Norman M. Greenberg, Ximing J. Yang, Luk Van Parijs, Seong-Jin Kim, Qiang Zhang, Michael R. Pins, Yinglu Guo, Chung Lee, Borko Javonovic, Timothy M. Kuzel, Victoria Liu
Publikováno v:
Cancer research. 65(5)
Transforming growth factor (TGF)-β is a potent immunosuppressant. Overproduction of TGF-β by tumor cells may lead to tumor evasion from the host immune surveillance and tumor progression. The present study was conducted to develop a treatment strat
Autor:
William J. Catalona, Nengwang Yu, Lin Chen, Brian T. Helfand, Charles B. Brendler, Beverly A. Teicher, Jay Harper, Qiang Zhang, Vidit Sharma, James M. Kozlowski, Thomas L. Jang, Ximing J. Yang, Chung Lee, Scott Lonning, Timothy M. Kuzel, Yinglu Guo, Lihua Julie Zhu, Borko Javonovic
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25168 (2011)
PLoS ONE
PLoS ONE
Background: DNA methyltransferase (DNMT) is one of the major factors mediating the methylation of cancer related genes such as TGF-b receptors (TbRs). This in turn may result in a loss of sensitivity to physiologic levels of TGF-b in aggressive prost