Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Bork A. Berghoff"'
Autor:
Daniel Edelmann, Bork A. Berghoff
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Bacterial persistence is a phenomenon that is founded by the existence of a subpopulation of multidrug-tolerant cells. These so-called persister cells endure otherwise lethal stress situations and enable restoration of bacterial populations upon retu
Externí odkaz:
https://doaj.org/article/3854fb2f9cf04b9ea3ade1a10763b7d2
Autor:
Daniel Edelmann, Florian H. Leinberger, Nicole E. Schmid, Markus Oberpaul, Till F. Schäberle, Bork A. Berghoff
Publikováno v:
Microorganisms, Vol 9, Iss 5, p 943 (2021)
Bacterial chromosomes harbor toxin-antitoxin (TA) systems, some of which are implicated in the formation of multidrug-tolerant persister cells. In Escherichia coli, toxin TisB from the tisB/istR-1 TA system depolarizes the inner membrane and causes A
Externí odkaz:
https://doaj.org/article/08fd1fe401374b4aa590a12c44859fc5
Publikováno v:
BioData Mining, Vol 10, Iss 1, Pp 1-20 (2017)
Abstract Background Measuring how gene expression changes in the course of an experiment assesses how an organism responds on a molecular level. Sequencing of RNA molecules, and their subsequent quantification, aims to assess global gene expression c
Externí odkaz:
https://doaj.org/article/c6941cf90aba4d87863157e1b5b1fab5
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Bacterial populations produce phenotypic variants called persisters to survive harmful conditions. Persisters are highly tolerant to antibiotics and repopulate environments after the stress has vanished. In order to resume growth, persisters have to
Externí odkaz:
https://doaj.org/article/e801b653c4464f7e97e74fd5800722ea
Autor:
Mathieu K. Licht, Aaron M. Nuss, Marcel Volk, Anne Konzer, Michael Beckstette, Bork A. Berghoff, Gabriele Klug
Publikováno v:
Microorganisms, Vol 8, Iss 2, p 283 (2020)
Photosynthetic bacteria have to deal with the risk of photooxidative stress that occurs in presence of light and oxygen due to the photosensitizing activity of (bacterio-) chlorophylls. Facultative phototrophs of the genus Rhodobacter adapt the forma
Externí odkaz:
https://doaj.org/article/bcfadb17bb5f4c04bf169718fab0e26d
Autor:
Tania S. Köbel, Rafael Melo Palhares, Christin Fromm, Witold Szymanski, Georgia Angelidou, Timo Glatter, Jens Georg, Bork A. Berghoff, Daniel Schindler
Publikováno v:
ACS Synthetic Biology. 11:2989-3003
Synthetic biology approaches life from the perspective of an engineer. Standardized and de novo design of genetic parts to subsequently build reproducible and controllable modules, for example, for circuit design, is a key element. To achieve this, n
Publikováno v:
Bioinformatics
SUMMARY: Synthetic small RNAs are gaining increasing attention in the field of synthetic biology and bioengineering for efficient post-transcriptional regulation of gene expression. However, the optimal design of synthetic small RNAs is challenging b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1359fdbb15a72f42b6049b202d15446f
https://hdl.handle.net/21.11116/0000-000D-06A0-7
https://hdl.handle.net/21.11116/0000-000D-06A0-7
Publikováno v:
Environmental Microbiology Reports. 13:159-168
Bacterial dormancy is a valuable strategy to endure unfavourable conditions. The term 'persister' has been coined for cells that tolerate antibiotic treatments due to reduced cellular activity. The type I toxin-antitoxin system tisB/istR-1 is linked
Publikováno v:
RNA Biol
DnaA is the initiator protein of chromosome replication, but the regulation of its homoeostasis in enterobacteria is not well understood. The DnaA level remains stable at different growth rates, suggesting a link between metabolism and dnaA expressio
Autor:
Bork A, Berghoff
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2357
State-of-the-art mass spectrometry enables in-depth analysis of proteomes in virtually all organisms. This chapter describes methods for the analysis of persister proteomes by mass spectrometry. Stable isotope labeling by amino acids in cell culture