Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Borislav Angelov"'
Autor:
Yu Wu, Borislav Angelov, Yuru Deng, Takehiko Fujino, Md Shamim Hossain, Markus Drechsler, Angelina Angelova
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract Cyclic-AMP-response element-binding protein (CREB) is a leucine zipper class transcription factor that is activated through phosphorylation. Ample CREB phosphorylation is required for neurotrophin expression, which is of key importance for p
Externí odkaz:
https://doaj.org/article/33017c9842b541c7b428e29307969fae
Autor:
Boris Kadinov, Aleksandar Shkondrov, Borislav Angelov, Ilina Krasteva, Magdalena Kondeva-Burdina
Publikováno v:
Pharmacia, Vol 70, Iss 1, Pp 15-19 (2023)
Flavonoids are one of the most popular antioxidants in plants. Their varied pharmacological activities are important for these compounds in order to add and to complement conventional therapy. Alcesefoliside and mauritianin are rare flavonol triglyco
Externí odkaz:
https://doaj.org/article/af7570587fe24c7b920342d73fd1d730
Autor:
Borislav Angelov, Emilio Mateev, Maya Georgieva, Virginia Tzankova, Magdalena Kondeva-Burdina
Publikováno v:
Pharmacia, Vol 69, Iss 4, Pp 1013-1017 (2022)
Four pyrrole based hydazide-hydrazones with established low hepatotoxicity and promising antiproliferative activity were evaluated (at 1µM concentration) for possible inhibitory activity on human isoforms of Cytochrome P450 CYP1A2, CYP3A4 and CYP2D6
Externí odkaz:
https://doaj.org/article/c66e130240f34ba1b8648d4c18ee54c3
Autor:
Miora Rakotoarisoa, Borislav Angelov, Markus Drechsler, Valérie Nicolas, Thomas Bizien, Yulia E. Gorshkova, Yuru Deng, Angelina Angelova
Publikováno v:
Smart Materials in Medicine, Vol 3, Iss , Pp 274-288 (2022)
We develop multidrug-loaded cubosome and spongosome lipid nanoparticles for targeting of endoplasmic reticulum stress as a potential emerging therapeutic strategy against neuronal degeneration. The multicompartment organization of the liquid crystall
Externí odkaz:
https://doaj.org/article/51556600705043c0a87265adb60ec440
Autor:
Magdalena Kondeva-Burdina, Emilio Mateev, Borislav Angelov, Virginia Tzankova, Maya Georgieva
Publikováno v:
Molecules, Vol 27, Iss 23, p 8485 (2022)
Parkinson’s disease is a huge burden in modern medicinal practice. A serious drawback of current antiparkinsonian therapy is its symptomatic nature. This directed our investigations in the search for new more potent derivatives, affecting not only
Externí odkaz:
https://doaj.org/article/574d0b61dd494e84b351ef17d75cfd41
Publikováno v:
ACS Omega, Vol 4, Iss 2, Pp 3061-3073 (2019)
Externí odkaz:
https://doaj.org/article/823f43f28ea9462ca9897cc6ffe8cf7d
Publikováno v:
Nanomaterials, Vol 12, Iss 13, p 2267 (2022)
Enabling challenging applications of nanomedicine and precision medicine in the treatment of neurodegenerative disorders requires deeper investigations of nanocarrier-mediated biomolecular delivery for neuronal targeting and recovery. The successful
Externí odkaz:
https://doaj.org/article/24ec692a40134105bb0e0e3bfb15691c
Autor:
Angelina Angelova, Borislav Angelov, Markus Drechsler, Thomas Bizien, Yulia E. Gorshkova, Yuru Deng
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Structural properties of plasmenyl-glycerophospholipids (plasmalogens) have been scarcely studied for plasmalogens with long polyunsaturated fatty acid (PUFA) chains, despite of their significance for the organization and functions of the cellular me
Externí odkaz:
https://doaj.org/article/0d5103df47174566b407fd5b031c2286
Publikováno v:
ACS Omega, Vol 3, Iss 3, Pp 3235-3247 (2018)
Externí odkaz:
https://doaj.org/article/e598c053d26a4f36b436d04a37dfa0c8
Autor:
Angelina Angelova, Borislav Angelov
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 6, Pp 886-889 (2017)
Among the macromolecular drug targets in neurodegenerative disorders, the neurotrophin brain-derived neurotrophic factor (BDNF) and its high-affinity tropomyosin-related kinase receptor (TrkB) present strong interest for nanomedicine development aimi
Externí odkaz:
https://doaj.org/article/7b921994408f457494e8d6a7133f640f