Zobrazeno 1 - 10
of 389
pro vyhledávání: '"Boris Zhivotovsky"'
Autor:
Pavel I. Volik, Alexey V. Zamaraev, Aleksandra Y. Egorshina, Nikolay V. Pervushin, Anastasia A. Kapusta, Pyotr A. Tyurin-Kuzmin, Anastasia V. Lipatova, Thilo Kaehne, Inna N. Lavrik, Boris Zhivotovsky, Gelina S. Kopeina
Publikováno v:
Cell Death and Disease, Vol 15, Iss 11, Pp 1-12 (2024)
Abstract Caspase-2 is a unique and conserved cysteine protease that is involved in several cellular processes, including different forms of cell death, maintenance of genomic stability, and the response to reactive oxygen species. Despite advances in
Externí odkaz:
https://doaj.org/article/cb975059e6da422e803602548237180d
Features of the CD1 gene family in rodents and the uniqueness of the immune system of naked mole-rat
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Cluster of Differentiation 1 (CD1) proteins are widely expressed throughout jawed vertebrates and present lipid antigens to specific CD1-restricted T lymphocytes. CD1 molecules play an important role in immune defense with the presence or ab
Externí odkaz:
https://doaj.org/article/3052f1d8d57a4ec9a1e05595de148ce6
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-34 (2024)
Abstract Background The mammalian ovary is a unique organ that displays a distinctive feature of cyclic changes throughout the entire reproductive period. The estrous/menstrual cycles are associated with drastic functional and morphological rearrange
Externí odkaz:
https://doaj.org/article/93ad78d9243b4b1ca28a9d4ac3b1a962
Autor:
Anna S. Gorbunova, Alexey V. Zamaraev, Maria A. Yapryntseva, Olga V. Kovaleva, Elena M. Tchevkina, Maria V. Turkina, Boris Zhivotovsky, Gelina S. Kopeina
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Lung cancer is the leading cause of cancer mortality worldwide. In recent years, the incidence of lung cancer subtype lung adenocarcinoma (LUAD) has steadily increased. Mitochondria, as a pivotal site of cell bioenergetics, metabolism, cell
Externí odkaz:
https://doaj.org/article/854c9a33f5314eb3ba33a2ecd9d814e7
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract Analysis of the toxicity of chemotherapeutic drugs is one of the main tasks of clinical pharmacology. Decreased viability of tumor cells may reflect two important physiological processes, namely the arrest of proliferation associated with di
Externí odkaz:
https://doaj.org/article/acef6cf81f5f445f809eb447769b589e
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-10 (2022)
Abstract Non-coding RNAs (ncRNAs) are a group of RNA molecules, such as small nucleolar RNAs, circular RNAs (circRNAs), microRNAs (miRNAs) and long-noncoding RNAs (ncRNAs), that do not encode proteins. Although their biofunctions are not well-underst
Externí odkaz:
https://doaj.org/article/2af95967d9ee413cbe2b74afbcfd72a9
Autor:
Elena V. Sazonova, Maria A. Yapryntseva, Nikolay V. Pervushin, Roman I. Tsvetcov, Boris Zhivotovsky, Gelina S. Kopeina
Publikováno v:
Cells, Vol 13, Iss 5, p 388 (2024)
The development of resistance to chemotherapy is one of the main problems for effective cancer treatment. Drug resistance may result from disturbances in two important physiological processes—cell proliferation and cell death. Importantly, both pro
Externí odkaz:
https://doaj.org/article/8644c797ed854f9bb7db3d830ea8ba64
Autor:
Petra Hååg, Magnus Olsson, Jeremy Forsberg, Marita Lagergren Lindberg, Bo Stenerlöw, Dali Zong, Lena Kanter, Rolf Lewensohn, Kristina Viktorsson, Boris Zhivotovsky, Leif Stenke
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-9 (2022)
Abstract The antibody conjugate gemtuzumab ozogamicin (GO; Mylotarg®) provides targeted therapy of acute myeloid leukemia (AML), with recent approvals for patients with CD33-positive disease at diagnosis or relapse, as monotherapy or combined with c
Externí odkaz:
https://doaj.org/article/3b05c0a5434345c7ad5ccfe8a8be06d6
Publikováno v:
Discover Oncology, Vol 12, Iss 1, Pp 1-11 (2021)
Abstract In order to maintain a functional mitochondrial network, cells have developed a quality control mechanism, namely mitophagy. This process can be induced through different pathways. The most studied is the so-called PINK1/Parkin pathway, whic
Externí odkaz:
https://doaj.org/article/19c9a79233374fc6bd88c22958758d8b
Publikováno v:
Biology Direct, Vol 16, Iss 1, Pp 1-11 (2021)
Abstract Although the phenomenon of mitotic catastrophe was first described more than 80 years ago, only recently has this term been used to explain a mechanism of cell death linked to delayed mitosis. Several mechanisms have been suggested for mitot
Externí odkaz:
https://doaj.org/article/3a76a226034a4270bb8aa44be03b9aea