Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Boris Vojnovic"'
Autor:
Srinivasa Rao, Clare Verrill, Lucia Cerundolo, Nasullah Khalid Alham, Zeynep Kaya, Miriam O’Hanlon, Alicia Hayes, Adam Lambert, Martha James, Iain D. C. Tullis, Jane Niederer, Shelagh Lovell, Altan Omer, Francisco Lopez, Tom Leslie, Francesca Buffa, Richard J. Bryant, Alastair D. Lamb, Boris Vojnovic, David C. Wedge, Ian G. Mills, Dan J. Woodcock, Ian Tomlinson, Freddie C. Hamdy
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-18 (2024)
Abstract Background Extension of prostate cancer beyond the primary site by local invasion or nodal metastasis is associated with poor prognosis. Despite significant research on tumour evolution in prostate cancer metastasis, the emergence and evolut
Externí odkaz:
https://doaj.org/article/fea0ecc091594c4e9bf661d9a47540cf
Autor:
Jeroen Claus, Gargi Patel, Flavia Autore, Audrey Colomba, Gregory Weitsman, Tanya N Soliman, Selene Roberts, Laura C Zanetti-Domingues, Michael Hirsch, Francesca Collu, Roger George, Elena Ortiz-Zapater, Paul R Barber, Boris Vojnovic, Yosef Yarden, Marisa L Martin-Fernandez, Angus Cameron, Franca Fraternali, Tony Ng, Peter J Parker
Publikováno v:
eLife, Vol 7 (2018)
While targeted therapy against HER2 is an effective first-line treatment in HER2+ breast cancer, acquired resistance remains a clinical challenge. The pseudokinase HER3, heterodimerisation partner of HER2, is widely implicated in the resistance to HE
Externí odkaz:
https://doaj.org/article/05bdc0b657ae488494f7ad21996d47c6
Autor:
Srinivasa Rao, Clare Verrill, Lucia Cerundolo, Nasullah Khalid Alham, Zeynep Kaya, Miriam O’Hanlon, Alicia Hayes, Adam Lambert, Martha James, Iain D. C. Tullis, Jane Niederer, Shelagh Lovell, Altan Omer, Francisco Lopez, Tom Leslie, Francesca Buffa, Richard J. Bryant, Alastair D. Lamb, Boris Vojnovic, David C. Wedge, Ian G. Mills, Dan J. Woodcock, Ian Tomlinson, Freddie C. Hamdy
Extension of prostate cancer beyond the primary site into the surrounding organs by local invasion or nodal metastasis is associated with poor prognosis. The emergence and evolution of cancer clones at this early stage of expansion and spread has not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5536552f419f740c8133217262863860
https://doi.org/10.1101/2023.02.27.530113
https://doi.org/10.1101/2023.02.27.530113
Autor:
Rose Ngu, Mark McGurk, Gopinath Gnanasegaran, Selvam Thavaraj, Boris Vojnovic, Clare Schilling
Publikováno v:
European Journal of Surgical Oncology. 46:2029-2034
Background Salivary cancer is rare and comprises a variety of histological subtypes and clinical behaviors. There is no agreed method of estimating the risk of occult metastasis or managing the clinically N0 neck.Sentinel node biopsy (SNB) may offer
Autor:
Paolo, Dell'Oglio, Elio, Mazzone, Tessa, Buckle, Tobias, Maurer, Nassir, Navab, Matthias N, van Oosterom, Clare, Schilling, Max Jh, Witjes, Alexander L, Vahrmeijer, Joachim, Klode, Boris, Vojnovic, Alexandre, Mottrie, Henk G, van der Poel, Freddie, Hamdy, Fijs Wb, van Leeuwen
Publikováno v:
Am J Nucl Med Mol Imaging
Developments within the field of image-guided surgery are ever expanding, driven by collective involvement of clinicians, researchers, and industry. While the general conception of the potential of image-guided surgery is to improve surgical outcome,
Autor:
Danny Allen, Stephen J. Lockett, Ruth J. Muschel, Tamar Yechezkel, Paul Kinchesh, Boris Vojnovic, Alastair D. Lamb, Hanna T. Sjoberg, Dina Preise, Richard J. Bryant, Jens Rittscher, Ka Ho Tam, Adrian L. Harris, Ian G. Mills, Yiannis Philippou, Anette L Magnussen, Iain D. C. Tullis, Emma A Murphy, Lilach Agemy, Freddie C. Hamdy, David A. Wink, Andrea Chatrian, Avigdor Scherz, Sean Smart, Joël Lefebvre, Stuart Gilchrist, Esther Bridges, David A. Scheiblin
Publikováno v:
Sjoberg, H T, Philippou, Y, Magnussen, A L, Tullis, I D C, Bridges, E, Chatrian, A, Lefebvre, J, Tam, K H, Murphy, E A, Rittscher, J, Preise, D, Agemy, L, Yechezkel, T, Smart, S C, Kinchesh, P, Gilchrist, S, Allen, D P, Scheiblin, D A, Lockett, S J, Wink, D A, Lamb, A D, Mills, I G, Harris, A, Muschel, R J, Vojnovic, B, Scherz, A, Hamdy, F C & Bryant, R J 2021, ' Tumour irradiation combined with vascular-targeted photodynamic therapy enhances antitumour effects in pre-clinical prostate cancer ', British Journal of Cancer, vol. 125, pp. 534-546 . https://doi.org/10.1038/s41416-021-01450-6
British Journal of Cancer
British Journal of Cancer
Background There is a need to improve the treatment of prostate cancer (PCa) and reduce treatment side effects. Vascular-targeted photodynamic therapy (VTP) is a focal therapy for low-risk low-volume localised PCa, which rapidly disrupts targeted tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e332f7007516e12e8126b136968964
https://pure.qub.ac.uk/en/publications/tumour-irradiation-combined-with-vasculartargeted-photodynamic-therapy-enhances-antitumour-effects-in-preclinical-prostate-cancer(a26d16da-6c3f-41e3-84f7-b20bf56280b2).html
https://pure.qub.ac.uk/en/publications/tumour-irradiation-combined-with-vasculartargeted-photodynamic-therapy-enhances-antitumour-effects-in-preclinical-prostate-cancer(a26d16da-6c3f-41e3-84f7-b20bf56280b2).html
Autor:
Spencer Bialek, Boris Vojnovic, Dylan Y. Breitkreutz, Christopher Daniel Johnstone, Paul Tsouchlos, Anthony Kavanagh, Zach Rovner, Thilakshan Kanesalingam, Magdalena Bazalova-Carter
Publikováno v:
Medical Physics. 46:2015-2024
The goal of this work was to develop and test a cylindrical tissue-equivalent quality assurance (QA) phantom for micro computed tomography (microCT) image-guided small animal irradiators that overcomes deficiencies of existing phantoms due to its mou
Autor:
Stephen J. Lockett, Lilach Agemy, Joel Loefebvre, Dina Preise, Richard J. Bryant, Iain D. C. Tullis, Boris Vojnovic, Avigdor Scherz, Hanna T. Sjoberg, Adrian L. Harris, Danny Allen, Alastair D. Lamb, Anette L Magnussen, Tamar Yechezkel, Yiannis Philippou, Ruth J. Muschel, Stuart Gilchrist, Ian G. Mills, Esther Bridges, David A. Scheiblin, Freddie C. Hamdy, David A. Wink, Paul Kinchesh, Jens Rittscher, Emma A Murphy, Ka Ho Tam, Andrea Chatrian, Sean Smart
RationaleThere is an important clinical need to improve the treatment of high risk localized and locally advanced prostate cancer (PCa), and to reduce the side effects of these treatments. We hypothesized that multi-modality therapy combining radioth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40253e120aea52b374e01dcb15dda989
https://doi.org/10.1101/2020.11.26.400283
https://doi.org/10.1101/2020.11.26.400283
Autor:
Paul R. Barber, Yosef Yarden, Roger George, Gargi Patel, Flavia Autore, Boris Vojnovic, Gregory Weitsman, Audrey Colomba, Marisa L. Martin-Fernandez, Selene K. Roberts, Peter J. Parker, Laura C. Zanetti-Domingues, Tony Ng, Michael Hirsch, Francesca Collu, Angus J.M. Cameron, Franca Fraternali, Tanya N. Soliman, Elena Ortiz-Zapater, Jeroen Claus
Publikováno v:
Claus, J, Patel, G, Autore, F, Colomba, A, Weitsman, G, Soliman, T N, Roberts, S, Zanetti Domingues, L C, Hirsch, M, Collu, F, George, R, Ortiz-Zapater, E, Barber, P R, Vojnovic, B, Yarden, Y, Martin-Fernandez, M L, Cameron, A, Fraternali, F, Ng, T & Parker, P J 2018, ' Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface ', eLife, vol. 7, e32271 . https://doi.org/10.7554/eLife.32271
eLife
eLife, Vol 7 (2018)
eLife
eLife, Vol 7 (2018)
While targeted therapy against HER2 is an effective first-line treatment in HER2+ breast cancer, acquired resistance remains a clinical challenge. The pseudokinase HER3, heterodimerisation partner of HER2, is widely implicated in the resistance to HE
Autor:
Francesca Collu, Tony Ng, Paul R. Barber, Jeroen Claus, Gargi Patel, Franca Fraternali, Gregory Weitsman, Angus J.M. Cameron, Michael Hirsch, Peter J. Parker, Roger George, Flavia Autore, Marisa L. Martin-Fernandez, Laura C. Zanetti-Domingues, Boris Vojnovic, Yosef Yarden, Tanya N. Soliman, Elena Ortiz-Zapater, Selene K. Roberts, Audrey Colomba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec3894b79dd4cc103426160cb78a6061
https://doi.org/10.7554/elife.32271.037
https://doi.org/10.7554/elife.32271.037