Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Boris V. Shilov"'
Autor:
Dmitry A. Dmitriev, Boris V. Shilov, Michail M. Polunin, Anton D. Zadorozhny, Alexey A. Lagunin
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17240 (2023)
Auditory neuropathy spectrum disorder (ANSD) associated with mutations of the OTOF gene is one of the common types of sensorineural hearing loss of a hereditary nature. Due to its high genetic heterogeneity, ANSD is considered one of the most difficu
Externí odkaz:
https://doaj.org/article/fb0d7b7edd2f4323b525b45b65f7613e
Publikováno v:
Life, Vol 13, Iss 9, p 1807 (2023)
Drug resistance to anticancer drugs is a serious complication in patients with cancer. Typically, drug resistance occurs due to amino acid substitutions (AAS) in drug target proteins. The study aimed at developing and validating a new approach to the
Externí odkaz:
https://doaj.org/article/7928706d4fe0491fb310e9323029a73d
Autor:
Alexey A. Lagunin, Maria A. Romanova, Anton D. Zadorozhny, Natalia S. Kurilenko, Boris V. Shilov, Pavel V. Pogodin, Sergey M. Ivanov, Dmitry A. Filimonov, Vladimir V. Poroikov
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Estimation of interaction of drug-like compounds with antitargets is important for the assessment of possible toxic effects during drug development. Publicly available online databases provide data on the experimental results of chemical interactions
Externí odkaz:
https://doaj.org/article/eadd412cfcc94ac4b99fb31fcd26d8e2
Autor:
Alexey Lagunin, V V Skarga, Boris V Shilov, Mikhail V. Malakhov, Mikhail A. Maslov, E V Nevezhin, A D Zadorozhny, Vadim V. Negrebetsky
Publikováno v:
Innate antiviral immunity.
Psoralens are medicinal photosensitizing furocoumarins which are used in photochemotherapy and photoimmunotherapy of dermatoses. Psoralen photooxidation products may be involved in therapeutic effects, but the possible mechanisms of their action rema
Autor:
Sergei N. Orlov, Svetlana V. Koltsova, Olga A. Akimova, Pavel Hamet, Johanne Tremblay, Boris V Shilov, Leonid V. Kapilevich, Julia G. Birulina, Mounsif Haloui, S. V. Gusakova
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 11, p e110597 (2014)
PLoS ONE, Vol 9, Iss 11, p e110597 (2014)
This study examines the relative impact of canonical hypoxia-inducible factor-1alpha- (HIF-1α and Na+ i/K+ i-mediated signaling on transcriptomic changes evoked by hypoxia and glucose deprivation. Incubation of RASMC in ischemic conditions resulted