Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Boris V, Chernyak"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Ferroptosis, a form of regulated cell death mediated by lipid peroxidation (LPO), has become the subject of intense research due to its potential therapeutic applications in cancer chemotherapy as well as its pathophysiological role in ischemic organ
Externí odkaz:
https://doaj.org/article/b35e3b8e20a240c7aad7b6a4e8409ea8
Autor:
Konstantin G. Lyamzaev, He Huan, Alisa A. Panteleeva, Ruben A. Simonyan, Armine V. Avetisyan, Boris V. Chernyak
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 730 (2024)
Lipid peroxidation plays an important role in various pathologies and aging, at least partially mediated by ferroptosis. The role of mitochondrial lipid peroxidation during ferroptosis remains poorly understood. We show that supplementation of exogen
Externí odkaz:
https://doaj.org/article/ad32d22f44b64d288a76ed595cc66194
Autor:
Ekaterina A. Golenkina, Galina M. Viryasova, Svetlana I. Galkina, Natalia D. Kondratenko, Tatjana V. Gaponova, Yulia M. Romanova, Konstantin G. Lyamzaev, Boris V. Chernyak, Galina F. Sud’ina
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Neutrophils play a primary role in protecting our body from pathogens. When confronted with invading bacteria, neutrophils begin to produce leukotriene B4, a potent chemoattractant that, in cooperation with the primary bacterial chemoattractant fMLP,
Externí odkaz:
https://doaj.org/article/07a0d956d4b640da871a328e8d97ec46
Publikováno v:
Cells, Vol 13, Iss 8, p 690 (2024)
The significant role of mast cells in the development of allergic and inflammatory diseases is well-established. Among the various mechanisms of mast cell activation, the interaction of antigens/allergens with IgE and the subsequent binding of this c
Externí odkaz:
https://doaj.org/article/c2817cb83fd040ed8ebbacf5010b22a3
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Oxidative stress nearly always accompanies all stages of cancer development. At the early stages, antioxidants may help to reduce reactive oxygen species (ROS) production and exhibit anticarcinogenic effects. In the later stages, ROS involvement beco
Externí odkaz:
https://doaj.org/article/b953ffddc57740808c43ce1f21776272
Autor:
Nina V. Vorobjeva, Maria A. Chelombitko, Galina F. Sud’ina, Roman A. Zinovkin, Boris V. Chernyak
Publikováno v:
Cells, Vol 12, Iss 18, p 2210 (2023)
Granulocytes (neutrophils, eosinophils, and basophils) are the most abundant circulating cells in the innate immune system. Circulating granulocytes, primarily neutrophils, can cross the endothelial barrier and activate various effector mechanisms to
Externí odkaz:
https://doaj.org/article/55b646b82b304621b03db23e7e2c66c5
Autor:
Galina F. Sud’ina, Ekaterina A. Golenkina, Anastasia S. Prikhodko, Natalia D. Kondratenko, Tatjana V. Gaponova, Boris V. Chernyak
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Leukotrienes are among the most potent mediators of inflammation, and inhibition of their biosynthesis, is becoming increasingly important in the treatment of many pathologies. In this work, we demonstrated that preincubation of human neutrophils wit
Externí odkaz:
https://doaj.org/article/ad502f5474484c5283bd8ea1298078b4
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/1c214e7a8982490ea49c72cbd3d11ce3
Autor:
Vladimir P. Skulachev, Mikhail Yu. Vyssokikh, Boris V. Chernyak, Armen Y. Mulkidjanian, Maxim V. Skulachev, Gregory A. Shilovsky, Konstantin G. Lyamzaev, Vitaliy B. Borisov, Fedor F. Severin, Victor A. Sadovnichii
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12540 (2023)
Cellular respiration is associated with at least six distinct but intertwined biological functions. (1) biosynthesis of ATP from ADP and inorganic phosphate, (2) consumption of respiratory substrates, (3) support of membrane transport, (4) conversion
Externí odkaz:
https://doaj.org/article/e0c1fa324f424ca8a9e70842da931f30
Autor:
Daniil A. Chernyavskij, Olga Yu. Pletjushkina, Anastasia V. Kashtanova, Ivan I. Galkin, Anna Karpukhina, Boris V. Chernyak, Yegor S. Vassetzky, Ekaterina N. Popova
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 602 (2023)
Many muscular pathologies are associated with oxidative stress and elevated levels of the tumor necrosis factor (TNF) that cause muscle protein catabolism and impair myogenesis. Myogenesis defects caused by TNF are mediated in part by reactive oxygen
Externí odkaz:
https://doaj.org/article/94462601efd44b7e802a994476d91685