Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Boris S Shenkman"'
Autor:
Yulia N Lomonosova, Boris S Shenkman, Grigorii R Kalamkarov, Tatiana Y Kostrominova, Tatyana L Nemirovskaya
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94448 (2014)
Eccentric exercise is known to disrupt sarcolemmal integrity and induce damage of skeletal muscle fibers. We hypothesized that L-arginine (L-Arg; nitric oxide synthase (NOS) substrate) supplementation prior to a single bout of eccentric exercise woul
Externí odkaz:
https://doaj.org/article/ad83b94666544df9b78e39c0840d1f4f
Autor:
Kristina A. Sharlo, Irina D. Lvova, Sergey A. Tyganov, Ksenia V. Sergeeva, Vitaly Y. Kalashnikov, Ekaterina P. Kalashnikova, Timur M. Mirzoev, Grigoriy R. Kalamkarov, Tatiana F. Shevchenko, Boris S. Shenkman
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 7, Pp 5613-5630 (2023)
Skeletal muscle disuse leads to pathological muscle activity as well as to slow-to-fast fiber-type transformation. Fast-type fibers are more fatigable than slow-type, so this transformation leads to a decline in muscle function. Prochlorperazine inje
Externí odkaz:
https://doaj.org/article/7c81d0e0556646f9bd2e1b8fbd1b2b27
Autor:
Timur M. Mirzoev, Inna I. Paramonova, Sergey V. Rozhkov, Ekaterina P. Kalashnikova, Svetlana P. Belova, Sergey A. Tyganov, Natalia A. Vilchinskaya, Boris S. Shenkman
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 4, Pp 3068-3086 (2023)
Currently, no ideal treatment exists to combat skeletal muscle disuse-induced atrophy and loss of strength. Because the activity of AMP-activated protein kinase (AMPK) in rat soleus muscle is suppressed at the early stages of disuse, we hypothesized
Externí odkaz:
https://doaj.org/article/05997466fa9b47ff9d3c3546c6030e78
Autor:
Kristina A. Sharlo, Irina D. Lvova, Sergey A. Tyganov, Ksenia A. Zaripova, Svetlana P. Belova, Tatiana Y. Kostrominova, Boris S. Shenkman, Tatiana L. Nemirovskaya
Publikováno v:
Biomolecules, Vol 13, Iss 9, p 1354 (2023)
Skeletal muscle abnormalities and atrophy during unloading are accompanied by the accumulation of excess calcium in the sarcoplasm. We hypothesized that calcium accumulation may occur, among other mechanisms, due to the inhibition of sarco/endoplasmi
Externí odkaz:
https://doaj.org/article/83c62eaa9271412c94f8a1a79dbb052a
Autor:
Natalia A. Vilchinskaya, Sergey V. Rozhkov, Olga V. Turtikova, Timur M. Mirzoev, Boris S. Shenkman
Publikováno v:
Cells, Vol 12, Iss 6, p 920 (2023)
Regrowth of atrophied myofibers depends on muscle satellite cells (SCs) that exist outside the plasma membrane. Muscle atrophy appears to result in reduced number of SCs due to apoptosis. Given reduced AMP-activated protein kinase (AMPK) activity dur
Externí odkaz:
https://doaj.org/article/c6433ea5a2994c25b30a1686a2bdb8eb
Autor:
Kristina A. Sharlo, Inna I. Paramonova, Irina D. Lvova, Natalia A. Vilchinskaya, Anna E. Bugrova, Tatiana F. Shevchenko, Grigoriy R. Kalamkarov, Boris S. Shenkman
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
It is known that nitric oxide (NO) may affect myosin heavy chain (MyHC) isoform mRNA transcription in skeletal muscles. The content of NO in soleus muscles decreases during rat hindlimb unloading as well as slow MyHC mRNA transcription. We aimed to d
Externí odkaz:
https://doaj.org/article/12c8feafe1cf41a8bde5ea9da98f7146
Publikováno v:
Pharmaceuticals, Vol 14, Iss 11, p 1167 (2021)
It is well known that reduced contractile activity of the main postural soleus muscle during long-term bedrest, immobilization, hindlimb unloading, and space flight leads to increased expression of fast isoforms and decreased expression of the slow i
Externí odkaz:
https://doaj.org/article/b858ef8b4b1f4fc0af047323449ffc27
Autor:
Vitaliy E. Kalashnikov, Sergey A. Tyganov, Olga V. Turtikova, Ekaterina P. Kalashnikova, Margarita V. Glazova, Timur M. Mirzoev, Boris S. Shenkman
Publikováno v:
Life, Vol 11, Iss 11, p 1161 (2021)
A gradual increase in rat soleus muscle electromyographic (EMG) activity is known to occur after 3–4 days of hindlimb suspension/unloading (HS). The physiological significance and mechanisms of such activity of motoneurons under unloading condition
Externí odkaz:
https://doaj.org/article/572c69f738104c5eb6db5538597c46a5
Autor:
Anna S. Berezovskaya, Sergey A. Tyganov, Svetlana D. Nikolaeva, Alexandra A. Naumova, Boris S. Shenkman, Margarita V. Glazova
Publikováno v:
Life, Vol 11, Iss 5, p 449 (2021)
Adult neurogenesis is a flexible process that depends on the environment and correlates with cognitive functions. Cognitive functions are impaired by various factors including space flight conditions and reduced physical activity. Physically active l
Externí odkaz:
https://doaj.org/article/e05f0d74911c434b93ce198028fe56e5
Autor:
Sergey A. Tyganov, Svetlana P. Belova, Olga V. Turtikova, Ivan M. Vikhlyantsev, Tatiana L. Nemirovskaya, Boris S. Shenkman
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 4141
Volume 24
Issue 4
Pages: 4141
Disuse muscle atrophy is usually accompanied by changes in skeletal muscle structure, signaling, and contractile potential. Different models of muscle unloading can provide valuable information, but the protocols of experiments with complete immobili