Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Boris R Belitsky"'
Autor:
Nadine Daou, Yuanguo Wang, Vladimir M Levdikov, Madhumitha Nandakumar, Jonathan Livny, Laurent Bouillaut, Elena Blagova, Keshan Zhang, Boris R Belitsky, Kyu Rhee, Anthony J Wilkinson, Xingmin Sun, Abraham L Sonenshein
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0206896 (2019)
Toxin synthesis and endospore formation are two of the most critical factors that determine the outcome of infection by Clostridioides difficile. The two major toxins, TcdA and TcdB, are the principal factors causing damage to the host. Spores are th
Externí odkaz:
https://doaj.org/article/88f5ccc2c5a14f20a04ef83f1d228a62
Publikováno v:
PLoS Genetics, Vol 11, Iss 10, p e1005600 (2015)
The global transcriptional regulator, CodY, binds strongly to the regulatory region of the braB gene, which encodes a Bacillus subtilis branched-chain amino acid (BCAA) permease. However, under conditions that maximize CodY activity, braB expression
Externí odkaz:
https://doaj.org/article/c62cf78b178f48b0a981ff7d5b5e3826
Publikováno v:
Mol Microbiol
CodY is a global transcriptional regulator that controls, directly or indirectly, the expression of dozens of genes and operons in Listeria monocytogenes. We used in vitro DNA affinity purification combined with massively parallel sequencing (IDAP-Se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c54942efa029b4d285a6d1039c2141
https://doi.org/10.1111/mmi.14449
https://doi.org/10.1111/mmi.14449
Publikováno v:
Journal of Bacteriology. 202
Listeria monocytogenes is a fastidious bacterial pathogen that can utilize only a limited number of nitrogen sources for growth. Both glutamine and ammonium are common nitrogen sources used in listerial defined growth media, but little is known about
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df7e205273443c0dd7a52890dfb787f0
https://doi.org/10.1128/jb.00209-20
https://doi.org/10.1128/jb.00209-20
Autor:
Gregory A. Petsko, Jose I. Juncosa, Boris R. Belitsky, Ruslan Sanishvili, Richard B. Silverman, Dali Liu, Hoang V. Le, Helaina J. Lehrer, Rui Wu, Michael Farley, Dagmar Ringe
Publikováno v:
Proceedings of the National Academy of Sciences. 114:3891-3896
The Bacillus subtilis protein regulator of the gabTD operon and its own gene (GabR) is a transcriptional activator that regulates transcription of γ-aminobutyric acid aminotransferase (GABA-AT; GabT) upon interactions with pyridoxal-5′-phosphate (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28788a5dae849c32807526818543bf3a
https://doi.org/10.1073/pnas.1703019114
https://doi.org/10.1073/pnas.1703019114
Publikováno v:
Mol Microbiol
D-Ala-D-Ala ligase, encoded by ddl genes, is responsible for the synthesis of a dipeptide, D-Ala-D-Ala, an essential precursor of bacterial peptidoglycan. In Clostridioides difficile, the single ddl gene is located upstream of the ddlR gene, which en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d038beedd36e73e833d0ca105dbc3a22
https://europepmc.org/articles/PMC6842417/
https://europepmc.org/articles/PMC6842417/
Autor:
Jonathan Livny, Elena Blagova, Abraham L. Sonenshein, Madhumitha Nandakumar, Yuanguo Wang, Keshan Zhang, Xingmin Sun, Nadine Daou, Anthony J. Wilkinson, Kyu Y. Rhee, Laurent Bouillaut, Vladimir M. Levdikov, Boris R. Belitsky
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0206896 (2019)
PLoS ONE
PLoS ONE
Toxin synthesis and endospore formation are two of the most critical factors that determine the outcome of infection by Clostridioides difficile. The two major toxins, TcdA and TcdB, are the principal factors causing damage to the host. Spores are th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c63e781b4bb9f14ed4fee56ed4b6cb65
https://eprints.whiterose.ac.uk/159482/1/journal.pone.0206896.pdf
https://eprints.whiterose.ac.uk/159482/1/journal.pone.0206896.pdf
Autor:
Ilya Borovok, Anat A. Herskovits, Nadejda Sigal, Lior Lobel, Boris R. Belitsky, Abraham L. Sonenshein
Publikováno v:
Molecular Microbiology. 95:624-644
Summary Metabolic adaptations are critical to the ability of bacterial pathogens to grow within host cells and are normally preceded by sensing of host-specific metabolic signals, which in turn can influence the pathogen's virulence state. Previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad89163846256c6b7d840e5870f83836
https://doi.org/10.1111/mmi.12890
https://doi.org/10.1111/mmi.12890
Autor:
Boris R. Belitsky
Publikováno v:
Molecular Microbiology. 92:1113-1128
Summary Listeria monocytogenes PdxR is a member of the poorly characterized but widespread group of MocR/GabR-type chimeric bacterial proteins that have DNA-binding and aminotransferase-like domains. Using mutational analysis, real-time RT-PCR, trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::216c88cc66cf55f42f4424f5f8150c15
https://doi.org/10.1111/mmi.12618
https://doi.org/10.1111/mmi.12618
Autor:
Dagmar Ringe, Thomas C. Terwilliger, Boris R. Belitsky, Roman Garcia, Cheryl A. Kreinbring, Gregory A. Petsko, Raji Edayathumangalam, Dali Liu, Rui Wu, Todd A. Stone, Quyen Q. Hoang, Yuguang Wang, Alicia Bach, Wei Wang, Jingling Liao
Publikováno v:
Proceedings of the National Academy of Sciences. 110:17820-17825
Bacillus subtilis GabR is a transcription factor that regulates gamma-aminobutyric acid (GABA) metabolism. GabR is a member of the understudied MocR/GabR subfamily of the GntR family of transcription regulators. A typical MocR/GabR-type regulator is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dcbd1623a81f385d5403b5cf0f1e54b
https://doi.org/10.1073/pnas.1315887110
https://doi.org/10.1073/pnas.1315887110