Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Boris Piskoun"'
Autor:
Molly J. Goodfellow, Lorena E. Hong, Boris Piskoun, Julie L. Proctor, Jody C. Cantu, Gary Fiskum
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Domestic ferrets (Mustela putorius furo) are an emerging model species in biomedical research. While behavioral studies are a critical translational tool for evaluating neurologic function in disease models and toxicology studies, there is a
Externí odkaz:
https://doaj.org/article/ab407b2513de45c6bf20bcc194d7987c
Autor:
Benjamin Drenger, Boris Piskoun, Esperanza Recio-Pinto, Alexandra Sideris, Thomas J. J. Blanck, E. Jaffrey
Publikováno v:
Journal of Cardiothoracic and Vascular Anesthesia. 33:1003-1011
Objectives Spinal cord ischemia secondary to trauma or a vascular occlusive event is a threatening phenomenon. The neuroprotective properties of minocycline have been shown in several models of central nervous system diseases and after spinal cord is
Autor:
Boris Piskoun, Esperanza Recio-Pinto, Monica Norcini, Daniel Choi, Mercedes Cano, Thomas J. J. Blanck, Helen Lu, Alicia Hurtado, Alexandra Sideris
Publikováno v:
Neuroscience. 386:223-239
In DRG an increase in miR-133b-3p, miR-143-3p, and miR-1-3p correlates with the lack of development of neuropathic pain following a peripheral nerve injury. Using lentiviral (LV) vectors we found that a single injection of LV-miR-133b-3p or LV-miR-14
Autor:
Monica Norcini, Esperanza Recio-Pinto, Boris Piskoun, Lori Russo, Thomas J. J. Blanck, Alexandra Sideris
Publikováno v:
Molecular Pain
Background The function of the Cannabinoid 1 receptor (CB1R) in the development of neuropathic pain is not clear. Mounting evidence suggest that CB1R expression and activation may contribute to pain. Cannabinoid 1 receptor knockout mice (CB1R−/−)
Publikováno v:
Acta Anaesthesiologica Scandinavica. 46:90-94
Background: There is substantial evidence that cholinomimetic drugs increase pain threshold. However, the profound side effects of these agents have limited their clinical use either as analgesics or as analgesic adjuncts. A delivery system that woul
Autor:
Fang Xu, Richard Kline, Andrew D. Rosenberg, Boris Piskoun, Thomas J. J. Blanck, Olga Eydlin, Esperanza Recio-Pinto, Lisa V. Doan
Background: Neuraxial local anesthetics may have neurological complications thought to be due to neurotoxicity. A primary site of action of local anesthetics is the dorsal root ganglia (DRG) neuron. Physiologic differences have been noted between you
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a14672344c94b037f0be30bb791a520e
https://europepmc.org/articles/PMC3947281/
https://europepmc.org/articles/PMC3947281/
Autor:
Gilbert J. Grant, Mylarrao Bansinath, Herman Turndorf, Boris Piskoun, Elijah M. Bolotin, Yechezkel Barenholz
Publikováno v:
Pharmaceutical Research. 18:336-343
Purpose. To evaluate the dehydration-rehydration technique to prepare a formulation of liposomal bupivacaine, and to assess its analgesic efficacy.
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 34:23-27
The development of tolerance to continuous morphine infusion (2, 4 and 6 mg x kg(-1) x hr(-1) was assessed in rats using two different methods for evaluation of nociception, tail flick (TF) and hot plate (HP). The influence of repeated testing on noc
Autor:
Fang Xu, Andrew D. Rosenberg, Boris Piskoun, Michael Phillips, Thomas J. J. Blanck, Lisa Doan
Publikováno v:
Obstetric Anesthesia Digest. 33:32-33
Chlorhexidine is recommended by several anesthesiology societies for antisepsis before regional anesthesia, but there is concern it may be neurotoxic. We evaluated the cytotoxicity of chlorhexidine and povidone-iodine in human neuronal and rat Schwan
Autor:
Elijah M. Bolotin, Yechezkel Barenholz, Mylarrao Bansinath, Elyad M. Davidson, Herman Turndorf, Boris Piskoun, Gilbert J. Grant
Publikováno v:
Anesthesiology. 101(1)
Background Currently available local anesthetics have relatively brief durations of action. An ultralong-acting local anesthetic would benefit patients with acute and chronic pain. The authors prepared and characterized a novel liposomal bupivacaine