Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Boris Pirlot"'
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Akademický článek
Intestinal permeability, microbial translocation, changes in duodenal and fecal microbiota, and their associations with alcoholic liver disease progression in humans
Autor: Luca Maccioni, Bei Gao, Sophie Leclercq, Boris Pirlot, Yves Horsmans, Philippe De Timary, Isabelle Leclercq, Derrick Fouts, Bernd Schnabl, Peter Stärkel
Publikováno v: Gut Microbes, Vol 12, Iss 1 (2020)
Background Animal data suggest a role of the gut-liver axis in progression of alcoholic liver disease (ALD), but human data are scarce especially for early disease stages. Methods We included patients with alcohol use disorder (AUD) who follow a reha
Externí odkaz: https://doaj.org/article/01d9971efef049e09e3b4bda4670b7ce
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2
Akademický článek
A Novel KRAS Antibody Highlights a Regulation Mechanism of Post-Translational Modifications of KRAS during Tumorigenesis
Autor: Mohamad Assi, Boris Pirlot, Vincent Stroobant, Jean-Paul Thissen, Patrick Jacquemin
Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 17, p 6361 (2020)
KRAS is a powerful oncogene responsible for the development of many cancers. Despite the great progress in understanding its function during the last decade, the study of KRAS expression, subcellular localization, and post-translational modifications
Externí odkaz: https://doaj.org/article/62b541cf12f24443b5769462a1a25355
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3
Toll-like receptor 2 activation in monocytes contributes to systemic inflammation and alcohol-associated liver disease in humans
Autor: Luca Maccioni, Joyce Kasavuli, Sophie Leclercq, Boris Pirlot, Géraldine Laloux, Yves Horsmans, Isabelle Leclercq, Bernd Schnabl, Peter Stärkel
Publikováno v: Hepatology communications, Vol. 7, no.5, p.-(2023)
In the context of gut leakiness and translocation of microbial products in alcohol-associated liver disease (ALD), it is possible that systemic and liver inflammation involve the activation of circulating monocyte through gut-derived factors. We expl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09ee50222d18a4b5ecfee9a399244dd
https://hdl.handle.net/2078.1/276369
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4
Abstract 4135: A novel plasma cell-based mechanism of action of adenosine immunomodulation and A2AR antagonism
Autor: Chiara Martinoli, Paola Tieppo, Marjorie Mercier, Hussein Shehade, Noemie Wald, Anais Vezzu, Annelise Hermant, Boris Pirlot, Stephanie Ma, Maurizio Ceppi, Yvonne McGrath, Maura Rossetti
Publikováno v: Cancer Research. 83:4135-4135
High levels of extracellular adenosine, often found in the tumor microenvironment (TME), promote immune suppression mainly through the A2A receptor (A2AR) expressed by tumor-infiltrating immune cells. Inupadenant (formerly known as EOS100850) is an o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c26b0a169ebe14c93840b563947d1ecb
https://doi.org/10.1158/1538-7445.am2023-4135
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6
Hypoxia protects the liver from Small For Size Syndrome: A lesson learned from the associated liver partition and portal vein ligation for staged hepatectomy (ALPPS) procedure in rats
Autor: Claude Bertrand, Valérie Lebrun, Boris Pirlot, Isabelle Leclercq, Alexandra Dili
Publikováno v: American Journal of Transplantation, Vol. 19, no. 11, p. 2979-2990 (2019)
American journal of transplantation, (2019)
Portal hyperperfusion and "dearterialization" of the liver remnant are the main pathogenic mechanisms for Small For Size syndrome (SFSS). Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) induces rapid remnant hypert
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b332f8a17b80397b4575c82c685fc014
https://doi.org/10.1111/ajt.15420
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7
Kras and Lkb1 mutations synergistically induce intraductal papillary mucinous neoplasm derived from pancreatic duct cells
Autor: Anne Couvelard, Isabelle Leclercq, Nora Meyers, Patrick Jacquemin, Mohamad Assi, Elsa Ghurburrun, Jérôme Cros, Mina Komuta, Louis Collet, Pieter Demetter, Boris Pirlot, Ivan Borbath, Frédéric P. Lemaigre
Publikováno v: Gut, Vol. 69, no. 4, p. 704-714 (2020)
ObjectivePancreatic cancer can arise from precursor lesions called intraductal papillary mucinous neoplasms (IPMN), which are characterised by cysts containing papillae and mucus-producing cells. The high frequency of KRAS mutations in IPMN and histo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8f4108c9e486c35ee2eadef2faa17a
https://hdl.handle.net/2078.1/216675
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8
Intestinal permeability, microbial translocation, changes in duodenal and fecal microbiota, and their associations with alcoholic liver disease progression in humans
Autor: Philippe de Timary, Isabelle Leclercq, Sophie Leclercq, Yves Horsmans, Luca Maccioni, Derrick E. Fouts, Peter Stärkel, Boris Pirlot, Bei Gao, Bernd Schnabl
Publikováno v: Gut microbes, Vol. 12, no.1, p. 1782157 (2020)
Gut Microbes, Vol 12, Iss 1 (2020)
Gut Microbes
article-version (VoR) Version of Record
Background Animal data suggest a role of the gut-liver axis in progression of alcoholic liver disease (ALD), but human data are scarce especially for early disease stages. Methods We included patients with alcohol use disorder (AUD) who follow a reha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581325dc2dba4a9ae2a8d4db99a1136b
https://hdl.handle.net/2078.1/236425
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