Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Boris P. Kopnin"'
Publikováno v:
Biochemistry (Moscow). 87:1199-1205
Lung and colorectal cancers are the most common types of cancer characterized by a poor prognosis and a high mortality rate. Mutations in the genes encoding components of the main intra- and extracellular signaling pathways, in particular the NOTCH1
Oncogenic mutations within RAS genes and inactivation of p53 are the most common events in cancer. Earlier, we reported that activated Ras contributes to chromosome instability, especially in p53-deficient cells. Here we show that an increase in intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60eb5080becc63b123b81e9e211649ea
https://doi.org/10.1158/0008-5472.c.6494789
https://doi.org/10.1158/0008-5472.c.6494789
Supplementary Figures 1-2 from Repression of Sestrin Family Genes Contributes to Oncogenic Ras-Induced Reactive Oxygen Species Up-regulation and Genetic Instability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3810f899a0e77ab813d54bef677c20f3
https://doi.org/10.1158/0008-5472.22365629.v1
https://doi.org/10.1158/0008-5472.22365629.v1
Publikováno v:
Annals of Oncology. 32:S1367
Publikováno v:
Annals of Oncology. 31:S1236
Publikováno v:
Annals of Oncology. 31:S1236
Publikováno v:
Russian Journal of Biotherapy. 15:6-14
Introduction. E-cadherin aberrant expression or complete loss is common for a number of human malignant neoplasms, and can be a launching mechanism of an epithelial-mesenchymal transition. Passing through epithelial-mesenchymal transition could in tu
Publikováno v:
Cell cycle (Georgetown, Tex.). 15(8)
Here we show that cancer stem cells amount in human lung adenocarcinoma cell line A549 depends on E-cadherin expression. In fact, downregulation of E-cadherin expression enhanced expression of pluripotent genes (c-MYC, NESTIN, OCT3/4 and SOX2) and en
Publikováno v:
ESMO Open. 3:A52-A53
Introduction There is increasing evidence that cancer stem cells (CSCs) could mediate resistance to chemo- and radiotherapy, metastasis and recurrence in a wide range of solid tumours. Notch signalling pathway is involved in CSCs maintenance. Notch i
Publikováno v:
ESMO Open. 3:A331-A332
Introduction Tumour microenvironment (TME) plays a crucial role in tumours initiation, progression and response to therapy. It is becoming increasingly clear that one of the most important promoters of tumour growth and progression is a subpopulation