Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Boris Negrutskii"'
Autor:
Boris Negrutskii
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
The human translation machinery includes three types of supramolecular complexes involved in elongation of the polypeptide chain: the ribosome, complex of elongation factors eEF1B and multienzyme aminoacyl-tRNA synthetase complex. Of the above, eEF1B
Externí odkaz:
https://doaj.org/article/ff58507dcf9d4a2a9bc586e2204cedbc
Publikováno v:
Biopolymers and Cell. 35:268-287
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57049c5e357744030b9c69ee91532cf9
https://doi.org/10.7124/bc.000a0a
https://doi.org/10.7124/bc.000a0a
Publikováno v:
IUBMB Life. 70:192-196
The question of what governs the translation elongation rate in eukaryotes has not yet been completely answered. Earlier, different availability of different tRNAs was considered as a main factor involved, however, recent data revealed that the elong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef6c30807fb4e060ffe0e4ebf6c438d6
https://doi.org/10.1002/iub.1724
https://doi.org/10.1002/iub.1724
Publikováno v:
Biopolymers and Cell, Vol 32, Iss 5, Pp 347-358 (2016)
Aim. To predict protein networks which may comprise the β subunit of the translation elongation complex eEF1B in lung carcinoma cell line. Methods. The protein partners of eEF1Bβ from cytoplasmic extract of A549 cells were identified by co-immunopr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b54a772b92c94f0dbddbe540731c9c7b
https://doi.org/10.7124/bc.00092f
https://doi.org/10.7124/bc.00092f
Publikováno v:
Biopolymers and Cell, Vol 32, Iss 1, Pp 9-20 (2016)
Translation elongation factor 1Bβ (eEF1Bβ) is a metazoan-specific protein catalyzing the guanine nucleotide exchange on translation elongation factor 1A (eEF1A). eEF1Bβ was reported to form oligomers. Aim. To define the structural region of human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47cd3a71ffa003e04d3affdf3478f7f6
https://doi.org/10.7124/bc.000907
https://doi.org/10.7124/bc.000907
Autor:
Boris Negrutskii, Nikolay Pydiura, Oleksandra V. Novosylna, Anna V. El'skaya, Agnieszka Góral, Ewelina Jurewicz, Anna Filipek
Publikováno v:
Biochimie. 119:137-145
Mammalian translation elongation factor eEF1A is involved in ribosomal polypeptide synthesis. Also, the protein fulfills many additional duties in an eukaryotic cell. Here, we identified a novel partner of the eEF1A1 isoform, namely Sgt1, a protein t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb1e9e8eba1c2e9ba1cb2d0ca2194df
https://doi.org/10.1016/j.biochi.2015.10.026
https://doi.org/10.1016/j.biochi.2015.10.026
Autor:
Dmytro M. Lozhko, Anna V. El'skaya, Michal Dadlez, Tetiana V. Bondarchuk, V. F. Shalak, Boris Negrutskii, Roman H. Szczepanowski, Agnieszka Fatalska
Publikováno v:
International journal of biological macromolecules. 126
Translation elongation factor 1Bβ (eEF1Bβ) is a metazoan-specific protein involved into the macromolecular eEF1B complex, containing also eEF1Bα and eEF1Bγ subunits. Both eEF1Bα and eEF1Bβ ensure the guanine nucleotide exchange on eEF1A while e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0f6022e81f63869817eb2f44ce583d
https://pubmed.ncbi.nlm.nih.gov/30590147
https://pubmed.ncbi.nlm.nih.gov/30590147
Aim. To review mechanisms of regulation of expression and the functionality of two isoforms of translation elongation factor eEF1A in mammalian cells. Results. eEF1A1 and eEF1A2 proteins are regulated by post-translational modifications, protein-prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49581e00080bbdb07881bdd99ecd4e5e
http://dspace.nbuv.gov.ua/handle/123456789/154368
http://dspace.nbuv.gov.ua/handle/123456789/154368
Aim. To identify novel protein partners of translation factor eEF1Bβ in nucleus of human lung carcinoma cells. Methods. Protein partners of eEF1Bβ in the nuclear fraction of A549 cells were identified by co-immunoprecipitation (co-IP) combined with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a1df555cdd6e536a072132cc5c91258
http://dspace.nbuv.gov.ua/handle/123456789/152980
http://dspace.nbuv.gov.ua/handle/123456789/152980
Autor:
A. I. Khoruzhenko, E. A. Egorova, V. F. Shalak, L. V. Skoroda, A. A. Mishin, M. I. Kovalenko, Boris Negrutskii, A. A. Vislovukh, Oleksandra V. Novosylna, M. S. Krotevych, E. F. Kolesanova
Publikováno v:
Biopolymers and Cell, Vol 30, Iss 6, Pp 454-461 (2014)
Aim. We intend to characterize the new peptide-specific antibodies against the isoform 2 of translation elongation factor 1A (eEF1A2) and determine its presence in the postoperative samples of human breast, lung and stomach tumor tissues. Methods. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360143d37ea51a581ad198df76159c21
http://biopolymers.org.ua/pdf/30/6/454/
http://biopolymers.org.ua/pdf/30/6/454/