Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Boris Mitsner"'
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:427-430
The knowledge of SAR in a series of biphenyl anionic RSV inhibitors has been broadened by synthesis and testing of analogs with pyrimidine linkers. Generally, pyrimidine compounds were much harder to synthesize, and their anti-RSV activity was lower
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d556ffc5d3906e76d85a460a73d66a0
https://doi.org/10.1016/j.bmcl.2004.10.056
https://doi.org/10.1016/j.bmcl.2004.10.056
Autor:
Mark Cutler, O'hara Bryan Mark, Antonia A. Nikitenko, Stanley A. Lang, Cynthia D. Hess, Yuri Raifeld, Yakov Gluzman, Girija Krishnamurthy, Boris Feld, George A. Ellestad, Boris Mitsner, Weidong Ding, Anna Gazumyan, Joe Zaccardi, Ann Aulabaugh
Publikováno v:
Journal of Medicinal Chemistry. 41:2671-2675
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee4d27a85c0616a4cd16983fa96aa2b
https://doi.org/10.1021/jm980239e
https://doi.org/10.1021/jm980239e
Autor:
Philip R. Wyde, Brian E. Gilbert, Wei-Dong Ding, O'hara Bryan Mark, Boris Mitsner, Donna K. Moore-Poveda
Publikováno v:
Antiviral Research. 38:31-42
CL387626 (4,4'-Bis[4,6-di[3-aminophenyl-N,N-bis(2-carbamoylethyl)-sulfon ilimino]-1,3,5-triazine-2-ylamino-bi-phenyl-2,2'-disulfonic acid, disodium salt), a compound synthesized by Wyeth-Ayerst Research Laboratories, was tested for its cytotoxicity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82dfa4bcba38bb6bf42e4efaed915c08
https://doi.org/10.1016/s0166-3542(98)00002-3
https://doi.org/10.1016/s0166-3542(98)00002-3
Autor:
Kitae Lim, John W. Ellingboe, Tarek S. Mansour, John O'Connell, Franklin J. Moy, Boris Feld, Antonia A. Nikitenko, Diane Grinberg, Geraldine Bebernitz, Matthew W. Olson, Ariamala Gopalsamy, Janis Upeslacis, Boris Mitsner
Publikováno v:
Journal of medicinal chemistry. 47(8)
Through high throughput screening of various libraries, substituted styryl naphthalene 6 was identified as an HCMV protease inhibitor. Optimization of various regions of the lead molecule using parallel synthesis resulted in 1,6-substituted naphthale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::714f4da5e18c5acd3a9e9ff60525b68a
https://pubmed.ncbi.nlm.nih.gov/15055990
https://pubmed.ncbi.nlm.nih.gov/15055990
Publikováno v:
Current pharmaceutical design. 6(5)
Human Respiratory Syncytial Virus (RSV) is considered to be the leading cause of lower respiratory tract disease in infants and young children. RSV is also a common pathogen in immunocompromised adults and in the elderly. RSV infection can be epidemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::296acff59630d8e35018c6fd03badb4e
https://pubmed.ncbi.nlm.nih.gov/10788595
https://pubmed.ncbi.nlm.nih.gov/10788595